Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jana Qiao"'
Autor:
Philipp Mertins, Dariusz Przybylski, Nir Yosef, Jana Qiao, Karl Clauser, Raktima Raychowdhury, Thomas M. Eisenhaure, Tanja Maritzen, Volker Haucke, Takashi Satoh, Shizuo Akira, Steven A. Carr, Aviv Regev, Nir Hacohen, Nicolas Chevrier
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2853-2866 (2017)
Building an integrated view of cellular responses to environmental cues remains a fundamental challenge due to the complexity of intracellular networks in mammalian cells. Here, we introduce an integrative biochemical and genetic framework to dissect
Externí odkaz:
https://doaj.org/article/78b5c7901c5847ab990bbd7395c9f727
Autor:
Tyler Jacks, Steven Carr, Frank Gertler, Anette Claudia Schafer, Jana Qiao, Philipp Mertins, Amanda del Rosario, Arjun Bhutkar, Rebecca Robbins, Kimberly Judith Dorans, Mandar Deepak Muzumdar, Pan-Yu Chen
Figures showing on-target effects of Kras knockdown in murine and human PDAC cells in vitro and in vivo, Gpr56 knockdown, SILAC and iTRAQ workflow and additional proteomics data, pharmacological inhibition of Src and FAK, and genetic inhibition of FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15517a443af9e6647647d5350f15a0cf
https://doi.org/10.1158/0008-5472.22417613.v1
https://doi.org/10.1158/0008-5472.22417613.v1
Autor:
Tyler Jacks, Steven Carr, Frank Gertler, Anette Claudia Schafer, Jana Qiao, Philipp Mertins, Amanda del Rosario, Arjun Bhutkar, Rebecca Robbins, Kimberly Judith Dorans, Mandar Deepak Muzumdar, Pan-Yu Chen
Activating mutations in KRAS are the hallmark genetic alterations in pancreatic ductal adenocarcinoma (PDAC) and the key drivers of its initiation and progression. Longstanding efforts to develop novel KRAS inhibitors have been based on the assumptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b742b7fa5c0f929b1e9293494ba7ae87
https://doi.org/10.1158/0008-5472.c.6509888
https://doi.org/10.1158/0008-5472.c.6509888
Autor:
Tyler Jacks, Steven Carr, Frank Gertler, Anette Claudia Schafer, Jana Qiao, Philipp Mertins, Amanda del Rosario, Arjun Bhutkar, Rebecca Robbins, Kimberly Judith Dorans, Mandar Deepak Muzumdar, Pan-Yu Chen
Detailed information on shRNA and primer sequences, tumor initiating frequency of Kras-inhibited cells, RNA-Seq data, and phosphoproteomic data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df09d774519746971c06e21a6f21562a
https://doi.org/10.1158/0008-5472.22417610.v1
https://doi.org/10.1158/0008-5472.22417610.v1
Autor:
Karl R. Clauser, Thomas Eisenhaure, Takashi Satoh, Nir Hacohen, Aviv Regev, Shizuo Akira, Steven A. Carr, Dariusz Przybylski, Tanja Maritzen, Jana Qiao, Volker Haucke, Nicolas Chevrier, Philipp Mertins, Nir Yosef, Raktima Raychowdhury
Publikováno v:
Cell reports, 19(13): 2853-2866
Cell Reports
Cell Reports, Vol 19, Iss 13, Pp 2853-2866 (2017)
Cell Reports
Cell Reports, Vol 19, Iss 13, Pp 2853-2866 (2017)
Building an integrated view of cellular responses to environmental cues remains a fundamental challenge due to the complexity of intracellular networks in mammalian cells. Here, we introduce an integrative biochemical and genetic framework to dissect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ec60cdc5389cd3af0b810609c69cbe
https://doi.org/10.1016/j.celrep.2017.06.016
https://doi.org/10.1016/j.celrep.2017.06.016
Autor:
Tyler Jacks, Kimberly Judith Dorans, Amanda M. Del Rosario, Steven A. Carr, Pan-Yu Chen, Anette C. Schafer, Frank B. Gertler, Rebecca Robbins, Philipp Mertins, Mandar Deepak Muzumdar, Arjun Bhutkar, Jana Qiao
Publikováno v:
PMC
Activating mutations in KRAS are the hallmark genetic alterations in pancreatic ductal adenocarcinoma (PDAC) and the key drivers of its initiation and progression. Longstanding efforts to develop novel KRAS inhibitors have been based on the assumptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fb9198d849c8463d2daf0d02d484ab
https://hdl.handle.net/1721.1/124410
https://hdl.handle.net/1721.1/124410
Autor:
Jana Qiao, Eric Kuhn, Tanya Svinkina, Shaunt Fereshetian, Jacob D. Jaffe, Steven A. Carr, Hongbo Gu, Philipp Mertins, Namrata D. Udeshi, Jeffrey C. Silva
Publikováno v:
Molecularcellular proteomics : MCP. 14(9)
Introduction of antibodies specific for acetylated lysine has significantly improved the detection of endogenous acetylation sites by mass spectrometry. Here, we describe a new, commercially available mixture of anti-lysine acetylation (Kac) antibodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b2a67b319c506178c8bde9ea844e56
https://pubmed.ncbi.nlm.nih.gov/25953088
https://pubmed.ncbi.nlm.nih.gov/25953088
Autor:
Kuan-lin Huang, Mehdi Mesri, Sherri R. Davies, Filip Mundt, Li Ding, Matthew J. Ellis, R. Reid Townsend, Kelly V. Ruggles, Francesca Petralia, Mani, Philipp Mertins, David Fenyö, Karl R. Clauser, Jing Wang, Michael A. Gillette, Pei Wang, Bing Zhang, Matthew D. Wilkerson, Song Cao, Michael D. McLellan, Chenwei Lin, Michael L. Gatza, Xianlong Wang, Charles M. Perou, Amanda G. Paulovich, Nci Cptac, Venkata Yellapantula, Zhidong Tu, Steven J. Skates, Ping Yan, Jana Qiao, Jonathan T. Lei, Christopher R. Kinsinger, Steven A. Carr, Henry Rodriguez
Publikováno v:
Molecular Cancer Research. 14:IA29-IA29
The genetic landscape of human breast cancer has been well defined in The Cancer Genome Atlas (TCGA) project. Mass spectrometry (MS)-based global proteome and phosphoproteome analyses provide a complementary, orthogonal approach to genomic studies to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67bcb82fbe65dcc2b0535bfcdd4fd793
https://doi.org/10.1158/1557-3125.advbc15-ia29
https://doi.org/10.1158/1557-3125.advbc15-ia29
Autor:
Li Ding, R. Reid Townsend, Zhanfang Guo, Jason M. Held, Shunqiang Li, Matthew J. Ellis, Kuan Huang, Mani, Jana Qiao, Matthew R. Meyer, Filip Mundt, Kelly V. Ruggles, Karl R. Clauser, Sherri R. Davies, David Fenyö, Steven A. Carr, Michael A. Gillette, Philipp Mertins, Cynthia X. Ma
Publikováno v:
Molecular Cancer Therapeutics. 14:C200-C200
AIM: The aim of this study was to identify markers that have the potential to predict BKM120 (a pan-class I PI3K inhibitor) effectiveness in triple negative breast cancer. INTRODUCTION: Triple negative breast cancer is an aggressive subtype that cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a75be5e83476371535ec82ed8bfa9fad
https://doi.org/10.1158/1535-7163.targ-15-c200
https://doi.org/10.1158/1535-7163.targ-15-c200
Autor:
Ping Yan, Sean Wang, Li Ding, Matthew J. Ellis, Song Cao, R. Reid Townsend, Mani, Henry Rodriguez, Michael L. Gatza, Kelly V. Ruggles, Bing Zhang, Philipp Mertins, David Fenyö, Sherri R. Davies, Pei Wang, Amanda G. Paulovich, Michael D. McLellan, Karl R. Clauser, Chenwei Lin, Jana Qiao, Steven A. Carr, Michael A. Gillette
Publikováno v:
Cancer Research. 75:SY44-02
The genetic landscape of human breast cancer has been well defined in The Cancer Genome Atlas (TCGA) project. Mass spectrometry (MS)-based global proteome and phosphoproteome analyses may provide an orthogonal approach to genomic studies to further i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287b12563f942745de5faf6687ce677d
https://doi.org/10.1158/1538-7445.am2015-sy44-02
https://doi.org/10.1158/1538-7445.am2015-sy44-02