Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jana Pourová"'
Publikováno v:
Nutrients, Vol 14, Iss 2, p 328 (2022)
Regular intake of polyphenol-rich food has been associated with a wide variety of beneficial health effects, including the prevention of cardiovascular diseases. However, the parent flavonoids have mostly low bioavailability and, hence, their metabol
Externí odkaz:
https://doaj.org/article/65b9327aada545399b52079ddcde6727
Autor:
Martin Doseděl, Eduard Jirkovský, Kateřina Macáková, Lenka Kujovská Krčmová, Lenka Javorská, Jana Pourová, Laura Mercolini, Fernando Remião, Lucie Nováková, Přemysl Mladěnka, on behalf of The OEMONOM
Publikováno v:
Nutrients, Vol 13, Iss 2, p 615 (2021)
Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its physiological role is much larger and encompasses very different processes ranging from facilitation of iron absorption through involvement in hormones and car
Externí odkaz:
https://doaj.org/article/01a9dec529854b3b82ba7d43378a4ae2
Publikováno v:
Nutrients, Vol 12, Iss 1, p 213 (2020)
Quercetin is proven to decrease arterial blood pressure when given orally. Its bioavailability is, however, low and, therefore, its metabolites could rather be responsible for this effect. In particular, the colonic metabolites of quercetin, 3,4-dihy
Externí odkaz:
https://doaj.org/article/9715dc003aa147a486e7ac0589e69282
Autor:
Jana Pourová, Lenka Applová, Kateřina Macáková, Marie Vopršalová, Thomas Migkos, Roger Bentanachs, David Biedermann, Lucie Petrásková, Václav Tvrdý, Marcel Hrubša, Jana Karlíčková, Vladimír Křen, Kateřina Valentová, Přemysl Mladěnka
Publikováno v:
Nutrients, Vol 11, Iss 10, p 2286 (2019)
Silymarin is a traditional drug and food supplement employed for numerous liver disorders. The available studies indicate that its activities may be broader, in particular due to claimed benefits in some cardiovascular diseases, but the contributions
Externí odkaz:
https://doaj.org/article/25c95dcbd8904239b0f3f87ab738b15e
Autor:
Jana Pourová, Přemysl Mladěnka, Lucia Mitašík, Iveta Nejmanová, Lucie Nováková, Maria Carmen Catapano, Hana Vlčková, Ondřej Kotland
Publikováno v:
Journal of Separation Science. 44:1893-1903
Sensitive analysis of very low-molecular weight metabolites using liquid chromatography with quadrupole-time-of-flight mass spectrometry is challenging due to the high losses of ions in a time-of-flight analyzer. Improvement in sensitivity for these
Autor:
Eduard Jirkovský, Přemysl Mladěnka, Václav Tvrdý, Kateřina Valentová, Jana Pourová, Vladimír Křen
Publikováno v:
Medicinal Research Reviews. 41:2195-2246
Silymarin is an extract from the seeds (fruits) of Silybum marianum that contains flavonolignans and flavonoids. Although it is frequently used as a hepatoprotective agent, its application remains somewhat debatable, in particular, due to the low ora
Autor:
Václav Tvrdý, Patrícia Dias, Iveta Nejmanová, Alejandro Carazo, Eduard Jirkovský, Jana Pourová, Jaka Fadraersada, Monika Moravcová, Lucija Peterlin Mašič, Marija Sollner Dolenc, Přemysl Mladěnka
Publikováno v:
Chemosphere. 313:137565
The human population is regularly exposed to bisphenols. The first compound of this class, bisphenol A, is burdened by numerous reports of its potential toxicity and has been hence replaced by its analogues, so-called next generation bisphenols. Thei
Publikováno v:
Nutrients
Nutrients; Volume 14; Issue 2; Pages: 328
Nutrients, Vol 14, Iss 328, p 328 (2022)
Nutrients; Volume 14; Issue 2; Pages: 328
Nutrients, Vol 14, Iss 328, p 328 (2022)
Regular intake of polyphenol-rich food has been associated with a wide variety of beneficial health effects, including the prevention of cardiovascular diseases. However, the parent flavonoids have mostly low bioavailability and, hence, their metabol
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:119
Autor:
Přemysl Mladěnka, Athina Geronikaki, Shamima Parvin, Patrícia Dias, Jana Karlíčková, Jana Pourová, Jaka Fadraersada, Elmira K. Hakobyan, Victor Kartsev, Marcel Hrubša, Anush A. Hovakimyan, Domenico Spinelli, Samvel N. Sirakanyan, Alejandro Carazo, Kateřina Macáková
Publikováno v:
The Journal of pharmacy and pharmacology. 74(6)
Objectives Both pyridine and pyrano derivatives have been previously shown to possess biologically relevant activity. In this study, we report the incorporation of these two scaffolds into one molecule. Methods The designed 3,3-dimethyl-6-oxopyrano[3