Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jana Pokludová"'
Autor:
Sára Lenárt, Peter Lenárt, Lucia Knopfová, Hana Kotasová, Vendula Pelková, Veronika Sedláková, Ondřej Vacek, Jana Pokludová, Vladimír Čan, Jan Šmarda, Karel Souček, Aleš Hampl, Petr Beneš
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract TACSTD2 encodes a transmembrane glycoprotein Trop2 commonly overexpressed in carcinomas. While the Trop2 protein was discovered already in 1981 and first antibody–drug conjugate targeting Trop2 were recently approved for cancer therapy, th
Externí odkaz:
https://doaj.org/article/ec7ff7a2fa694aecb1011c9f0a61909f
Publikováno v:
Journal of Cellular and Molecular Medicine
An acidic environment and hypoxia within the tumour are hallmarks of cancer that contribute to cell resistance to therapy. Deregulation of the PI3K/Akt pathway is common in colon cancer. Numerous Akt-targeted therapies are being developed, the activi
Autor:
Adamová, Barbora, Říhová, Kamila, Pokludová, Jana, Beneš, Petr, Šmarda, Jan, Navrátilová, Jarmila
Publikováno v:
Journal of Cellular & Molecular Medicine; Jan2023, Vol. 27 Issue 1, p76-88, 13p