Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Jana Pachlopnik"'
Autor:
Olivia Jorisch-Mühlebach, Dina Pitts, Raphaela Tinner, Hong Ying Teh, Conrad Roelli, Seraina Prader, Stefano Vavassori, Jana Pachlopnik Schmid
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHemophagocytic lymphohistiocytosis (HLH) is a life-threatening immune disorder characterized by uncontrolled lymphocyte and macrophage activation and a subsequent cytokine storm. The timely initiation of immunosuppressive treatment is cru
Externí odkaz:
https://doaj.org/article/ea8149a3463a4741afe33a43ffb7b85b
Autor:
Maya C. Andre, Carlos Sanchez, Sabrina Bressieux-Degueldre, Marie-Helene Perez, Daniela Wütz, Geraldine Blanchard-Rohner, Serge Grazioli, Nina Schöbi, Johannes Trück, Tatjana Welzel, Andrew Atkinson, Luregn J. Schlapbach, Julia Bielicki, Henrik Koehler, Spyridoula Gysi, Indra Janz, Andreas Bieri, Birgit Donner, Jürg Hammer, Ulrich Heininger, Clemens von Kalckreuth, Malte Kohns, Nicole Mettauer, Alexandra Meyer, Diana Reppucci, Chloé Schlaeppi, Daniel Trachsel, Nina Vaezipour, Andreas Woerner, Andreas Zutter, Federica Vanoni, Lisa Kottanattu, Calogero Mazzara, Alessia Severi Conti, Christoph Aebi, Philipp Agyeman, Andrea Duppenthaler, Martin Glöckler, Sabine Pallivathukal, Thomas Riedel, Petra Zimmermann, Hong-Phuc Cudré-Cung, Mladen Pavlovic, Alice Bordessoule, Anne-Laure Martin, Angelo Polito, Noemie Wagner, Marie Rohr, Arnaud L'Huillier, Vivianne Amiet, Thomas Ferry, David Longchamp, Julia Natterer, Rebecca Oppenheim, Michael Hofer, Michael Buettcher, Katharina Wechselberger, Alex Donas, Sara Germann, Michaela Lütolf Erni, Daniela Kaiser, Katharina Schwendener Scholl, Hans Peter Kuen, Katja Hrup, Janine Stritt, Douggl G.N. Bailey, Tanja Wachinger, Ingrid Beck, André Birkenmaier, Bjarte Rogdo, Philip Lorenz, Ivo Iglowstein, Konstanze Zöhrer, Martin Flade, Seraina Prader, Jana Pachlopnik Schmid, Michelle Seiler, Patrick Meyer Sauteur, Barbara Brotschi, Kathrin Weber, Elizabeth Whittaker, Saul N. Faust
Publikováno v:
EClinicalMedicine, Vol 67, Iss , Pp 102358- (2024)
Summary: Background: Previous findings from the Swissped RECOVERY trial showed that patients with Pediatric Inflammatory Multisystem Syndrome–Temporally Associated with SARS-CoV-2 (PIMS-TS) who were randomly assigned to intravenous immunoglobulins
Externí odkaz:
https://doaj.org/article/1d9314edfd444a7c9a33e4b0ed2aafa7
Autor:
Christine Engelmann, Patrick Schuhmachers, Hana Zdimerova, Sanamjeet Virdi, Mathias Hauri-Hohl, Jana Pachlopnik Schmid, Adam Grundhoff, Rebecca A. Marsh, Wendy Wei-Lynn Wong, Christian Münz
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-13 (2022)
Abstract X-linked lymphoproliferative disease (XLP) is either caused by loss of the SLAM-associated protein (SAP; XLP-1) or the X-linked inhibitor of apoptosis (XIAP; XLP-2). In both instances, infection with the oncogenic human Epstein Barr virus (E
Externí odkaz:
https://doaj.org/article/a0e5da340b41418f9bd4969add63331b
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cytotoxic lymphocytes kill target cells through polarized release of the content of cytotoxic granules towards the target cell. The importance of this cytotoxic pathway in immune regulation is evidenced by the severe and often fatal condition, known
Externí odkaz:
https://doaj.org/article/3851bee88a7a449cac705f33439384dd
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Jacobsen syndrome is a rare genetic disorder associated with a terminal deletion in chromosome 11. The clinical presentation is variable. Although immunodeficiency has been described in patients with Jacobsen syndrome, a clear genotype-phenotype corr
Externí odkaz:
https://doaj.org/article/7b9cda994c7a496fb6c7db902f096822
Autor:
Caroline Vinit, Sophie Georgin-Lavialle, Aikaterini Theodoropoulou, Catherine Barbier, Alexandre Belot, Manel Mejbri, Pascal Pillet, Jana Pachlopnik, Sylvaine Poignant, Charlotte Rebelle, Andreas Woerner, Isabelle Koné-Paut, Véronique Hentgen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundInterleukin (IL)-1 inhibitors represent the main treatment in patients with colchicine-resistant/intolerant familial Mediterranean fever (crFMF), mevalonate kinase deficiency (MKD), and tumor necrosis factor receptor-associated periodic syn
Externí odkaz:
https://doaj.org/article/26ad2c1c806644ef91dc77d124b1103b
Autor:
Seraina Prader, Nicole Ritz, Frédéric Baleydier, Maya C. Andre, Noémie Stähli, Kevin Schmid, Hanna Schmid, Andreas Woerner, Tamara Diesch, Patrick M. Meyer Sauteur, Johannes Trück, Fabienne Gebistorf, Lennart Opitz, Michael P. Killian, Tommaso Marchetti, Stefano Vavassori, Géraldine Blanchard-Rohner, Valerie Mc Lin, Serge Grazioli, Jana Pachlopnik Schmid
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Most children with a SARS-CoV-2 infection are asymptomatic or exhibit mild symptoms. However, a small number of children develop features of substantial inflammation temporarily related to the COVID-19 also called multisystem inflammatory syndrome in
Externí odkaz:
https://doaj.org/article/cbd380dbb52849c9a76aad4a279f95f7
Autor:
Luregn J. Schlapbach, Maya C. Andre, Serge Grazioli, Nina Schöbi, Nicole Ritz, Christoph Aebi, Philipp Agyeman, Manuela Albisetti, Douggl G. N. Bailey, Christoph Berger, Géraldine Blanchard-Rohner, Sabrina Bressieux-Degueldre, Michael Hofer, Arnaud G. L'Huillier, Mark Marston, Patrick M. Meyer Sauteur, Jana Pachlopnik Schmid, Marie-Helene Perez, Bjarte Rogdo, Johannes Trück, Andreas Woerner, Daniela Wütz, Petra Zimmermann, Michael Levin, Elizabeth Whittaker, Peter C. Rimensberger, the PIMS-TS working group of the Interest Group for Pediatric Neonatal Intensive Care (IGPNI) of the Swiss Society of Intensive Care and the Pediatric Infectious Diseases Group Switzerland (PIGS)
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: Following the spread of the coronavirus disease 2019 (COVID-19) pandemic a new disease entity emerged, defined as Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or Multisystem Inflammatory Syndr
Externí odkaz:
https://doaj.org/article/55db27dd5e5249a1874b4e5d1d90a949
Autor:
Abhilash Kannan, Maarit Suomalainen, Romain Volle, Michael Bauer, Marco Amsler, Hung V. Trinh, Stefano Vavassori, Jana Pachlopnik Schmid, Guilherme Vilhena, Alberto Marín-González, Ruben Perez, Andrea Franceschini, Christian von Mering, Silvio Hemmi, Urs F. Greber
Publikováno v:
Viruses, Vol 14, Iss 7, p 1407 (2022)
Pathogen-associated molecular patterns, including cytoplasmic DNA and double-strand (ds)RNA trigger the induction of interferon (IFN) and antiviral states protecting cells and organisms from pathogens. Here we discovered that the transfection of huma
Externí odkaz:
https://doaj.org/article/6360a00204eb4ea78f58a9ba03567744
Autor:
Athina Fouriki, Yves Fougère, Caroline De Camaret, Géraldine Blanchard Rohner, Serge Grazioli, Noémie Wagner, Christa Relly, Jana Pachlopnik Schmid, Johannes Trück, Lisa Kottanatu, Estefania Perez, Marie-Helene Perez, Damien Schaffner, Sandra Andrea Asner, Michael Hofer
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2021)
Since the beginning of the severe SARS-CoV-2 pandemic, an increasing number of countries reported cases of a systemic hyperinflammatory condition defined as multi-system inflammatory syndrome in children (MIS-C). The clinical features of MIS-C can be
Externí odkaz:
https://doaj.org/article/455415d962d244d290798033fdcbeb7a