Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jana P. Lim"'
Publikováno v:
International Journal of Noncommunicable Diseases, Vol 1, Iss 1, Pp 42-43 (2016)
Externí odkaz:
https://doaj.org/article/8aaff2dc8c714887969fc7d31321a928
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50594 (2012)
Neuronal signal transduction by the JNK MAP kinase pathway is altered by a broad array of stimuli including exposure to the widely abused drug ethanol, but the behavioral relevance and the regulation of JNK signaling is unclear. Here we demonstrate t
Externí odkaz:
https://doaj.org/article/cbafb9abeeee4393a51f68f10deb2249
Publikováno v:
PLoS Genetics, Vol 5, Iss 11, p e1000706 (2009)
Mutations affecting the heritable maintenance of epigenetic states in maize identify multiple small RNA biogenesis factors including NRPD1, the largest subunit of the presumed maize Pol IV holoenzyme. Here we show that mutations defining the required
Externí odkaz:
https://doaj.org/article/3e3e9753ac5c4b6bb676c8a5367a5015
The ability to adapt behavior to environmental fluctuations is critical for survival of organisms ranging from invertebrates to mammals.Caenorhabditis eleganscan learn to avoid sodium chloride when it is paired with starvation. This behavior is likel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ceb93f0e5d02766d328a6d605403d89
https://doi.org/10.1101/149682
https://doi.org/10.1101/149682
Publikováno v:
Alcoholism: Clinical and Experimental Research. 38:170-178
Background Prkcz has been identified as a gene whose expression is positively correlated with ethanol (EtOH) consumption in mice and is also induced by EtOH. Two proteins are produced from Prkcz: protein kinase M zeta (PKMζ), which is expressed in t
Autor:
Benjamin R. Kanter, Jahan Dadgar, Mimi E. Zou, Anna M. Lee, Sarah C. Fischbach-Weiss, Robert O. Messing, Dan Dan Wang, Thomas A. McMahon, Jana P. Lim, Chichen Qiu
Publikováno v:
Nature
Protein kinase M-ζ (PKM-ζ) is a constitutively active form of atypical protein kinase C that is exclusively expressed in the brain and implicated in the maintenance of long-term memory. Most studies that support a role for PKM-ζ in memory maintena
Autor:
Jungsoo Lee, Chang Hoon Jee, Jana P. Lim, Dianne Parry, Steven L. McIntire, Robert O. Messing
Publikováno v:
Genes, Brain and Behavior. 12:250-262
The CRF (corticotropin-releasing factor) system is a key mediator of the stress response. Alterations in CRF signaling have been implicated in drug craving and ethanol consumption. The development of negative reinforcement via activation of brain str
Publikováno v:
Genes, Brain and Behavior. 12:87-97
Despite recent advances in the understanding of ethanol's biological action, many of the molecular targets of ethanol and mechanisms behind ethanol's effect on behavior remain poorly understood. In an effort to identify novel genes, the products of w
Autor:
Alice Barkan, Jerry L. Kermicle, Joy-El R. Barbour, Rosalind Williams-Carrier, Susan E. Parkinson, Clarissa C. Lee, Jana P. Lim, Irene T. Liao, Blake C. Meyers, Stacey A. Simon, Jay B. Hollick, Jennifer L. Stonaker
Publikováno v:
The Plant Cell. 24:1761-1775
Meiotically heritable epigenetic changes in gene regulation known as paramutations are facilitated by poorly understood trans-homolog interactions. Mutations affecting paramutations in maize (Zea mays) identify components required for the accumulatio
Publikováno v:
Brain and Behavior
Brain and behavior, vol 2, iss 1
Brain and behavior, vol 2, iss 1
Although genetic background alters responses to ethanol, there has not yet been a methodical quantification of differences in ethanol-related behaviors between inbred and hybrid mice commonly used in gene-targeting studies. Here, we compared C57BL/6N