Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jana N Radin"'
Autor:
Jana N Radin, Jessica L Kelliher, Paola K Párraga Solórzano, Kyle P Grim, Rouhallah Ramezanifard, James M Slauch, Thomas E Kehl-Fie
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007971 (2019)
The ability of Staphylococcus aureus and other pathogens to consume glucose is critical during infection. However, glucose consumption increases the cellular demand for manganese sensitizing S. aureus to host-imposed manganese starvation. The current
Externí odkaz:
https://doaj.org/article/7b023c0d80744da4b0ea9daddb491223
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1006040 (2016)
During infection the host imposes manganese and zinc starvation on invading pathogens. Despite this, Staphylococcus aureus and other successful pathogens remain capable of causing devastating disease. However, how these invaders adapt to host-imposed
Externí odkaz:
https://doaj.org/article/b7047a69f1cf48c9a2f99135d8904540
Autor:
Beverly R E A Dixon, Jana N Radin, M Blanca Piazuelo, Diana C Contreras, Holly M Scott Algood
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148514 (2016)
Helicobacter pylori colonization of the human stomach can lead to adverse clinical outcomes including gastritis, peptic ulcers, or gastric cancer. Current data suggest that in addition to bacterial virulence factors, the magnitude and types of immune
Externí odkaz:
https://doaj.org/article/14131992ab5b477fae0bdb2b4cad2232
Autor:
Jennifer A Gaddy, Jana N Radin, John T Loh, M Blanca Piazuelo, Thomas E Kehl-Fie, Alberto G Delgado, Florin T Ilca, Richard M Peek, Timothy L Cover, Walter J Chazin, Eric P Skaar, Holly M Scott Algood
Publikováno v:
PLoS Pathogens, Vol 10, Iss 10, p e1004450 (2014)
Transition metals are necessary for all forms of life including microorganisms, evidenced by the fact that 30% of all proteins are predicted to interact with a metal cofactor. Through a process termed nutritional immunity, the host actively sequester
Externí odkaz:
https://doaj.org/article/ac24f7971a53476f94e4cccfb96bf4d1
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60363 (2013)
Helicobacter pylori infection leads to an inflammatory response in 100% of infected individuals. The inflammatory cells which are recruited to the gastric mucosa during infection produce several pro- and anti-inflammatory cytokines including several
Externí odkaz:
https://doaj.org/article/24db63f392c54263980bac7d87b9c1a0
Autor:
Saika Hossain, Jacqueline R Morey, Stephanie L Neville, Katherine Ganio, Jana N Radin, Javiera Norambuena, Jeff M Boyd, Christopher A. McDevitt, Thomas E. Kehl-Fie
Publikováno v:
bioRxiv
Microorganisms can acquire metal ions in metal-limited environments using small molecules called metallophores. While metals and their importers are essential, metals can also be toxic, and metallophores have limited ability to discriminate metals. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcc45b0c132e57b3b30aee289f5b69e
https://europepmc.org/articles/PMC10312489/
https://europepmc.org/articles/PMC10312489/
Autor:
Gilberto C. Padron, Alexander M. Shuppara, Anuradha Sharma, Matthias D. Koch, Jessica-Jae S. Palalay, Jana N. Radin, Thomas E. Kehl-Fie, James A. Imlay, Joseph E. Sanfilippo
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Cells regularly experience fluid flow in natural systems. However, most experimental systems rely on batch cell culture and fail to consider the effect of flow-driven dynamics on cell physiology. Using microfluidics and single-cell imaging, we discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2957aa9c19435ee00b80a14a21c38aa
https://doi.org/10.1073/pnas.2216774120
https://doi.org/10.1073/pnas.2216774120
Publikováno v:
mBio.
The preferred carbon source of Staphylococcus aureus and many other pathogens is glucose, and its consumption is critical during infection. However, glucose utilization increases the cellular demand for manganese, a nutrient sequestered by the host a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba35e7cb3b4f428909740683d01aae8
https://pubmed.ncbi.nlm.nih.gov/36598285
https://pubmed.ncbi.nlm.nih.gov/36598285
Autor:
Gilberto C. Padron, Alexander M. Shuppara, Anuradha Sharma, Matthias D. Koch, Jessica-Jae S. Palalay, Jana N. Radin, Thomas E. Kehl-Fie, James A. Imlay, Joseph E. Sanfilippo
Cells regularly experience fluid flow in natural systems. However, most experimental systems rely on batch cell culture and fail to consider the effect of flow-driven dynamics on cell physiology. Using microfluidics and single-cell imaging, we discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f8e6717c3c3808e22544fbe36cbacf
https://doi.org/10.1101/2022.09.07.506966
https://doi.org/10.1101/2022.09.07.506966
Autor:
Lindsey R. Burcham, Madeline S. Akbari, Norhan Alhajjar, Rebecca A. Keogh, Jana N. Radin, Thomas E. Kehl-Fie, Ashton T. Belew, Najib M. El-Sayed, Kevin S. McIver, Kelly S. Doran
Publikováno v:
mBio. 13
Morbidity and mortality associated with GBS begin with colonization of the female reproductive tract (FRT). To date, our understanding of the factors required for GBS persistence in this environment remain limited.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babffd33b3c931c503c6d84c02784878
https://doi.org/10.1128/mbio.00985-22
https://doi.org/10.1128/mbio.00985-22