Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jana Lucenicova"'
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Akademický článek
Analytical and Sample Preparation Protocol for Therapeutic Drug Monitoring of 12 Thiopurine Metabolites Related to Clinical Treatment of Inflammatory Bowel Disease
Autor: Daniel Pecher, Svetlana Dokupilová, Zuzana Zelinková, Maikel Peppelenbosch, Jana Lučeničová, Veronika Mikušová, Peter Mikuš
Publikováno v: Molecules, Vol 23, Iss 7, p 1744 (2018)
Thiopurines (TP) represent an important therapeutic tool for the treatment of inflammatory bowel diseases (IBD) in the current situation of rising incidence and health care costs. The results of multiple clinical studies aimed at finding correlations
Externí odkaz: https://doaj.org/article/a031652354bf4ff39d9d6089a7d4e30a
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2
Porous graphitic carbon based chromatography hyphenated with mass spectrometry: A new strategy for profiling thiopurine nucleotides in patients with inflammatory bowel diseases
Autor: Peter Mikuš, Zuzana Zelinkova, Svetlana Dokupilová, Veronika Mikušová, Daniel Pecher, Jana Lucenicova, Maikel P. Peppelenbosch
Publikováno v: Analytica Chimica Acta, 1137, 64-73. Elsevier
Thiopurine (TP) treatment is discontinued in up to 30% of patients suffering from inflammatory bowel diseases (IBD) due to various adverse effects. Therapeutic drug monitoring of biologically active TP metabolites, i.e. thiopurine nucleotides (TPN),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb82a10f09e18148cdf7fe3b34566c1
https://pubmed.ncbi.nlm.nih.gov/33153610
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3
P303 Local Application of Autologous Platelet-rich Plasma leads to Sustained Healing of Crohn’s Perianal Fistulae – One Year follow-up Results from a Single Center Pilot Study
Autor: D. Podmanicky, M Jezberova, B Kadleckova, Zuzana Zelinkova, V Bak, Jana Lucenicova
Publikováno v: Journal of Crohn's and Colitis. 15:S331-S332
Background Failure of wound repair and dysregulated inflammation in considered to play a key role in the persistence of Crohn’s perianal fistulae (pCD). Few preliminary reports suggest that autologous platelet-rich plasma (PRP) can enhance wound re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14d835d56e5138799b1f8c416c4039ab
https://doi.org/10.1093/ecco-jcc/jjab076.427
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4
P470 Ustekinumab Trough Levels are not Associated with Clinical Response in Inflammatory Bowel Disease Patients
Autor: A Lipovska, B Kadleckova, Zuzana Zelinkova, Jana Lucenicova, K Otottova
Publikováno v: Journal of Crohn's and Colitis. 15:S460-S461
Background Ustekinumab (UST) has been shown to effectively induce and maintain remission in inflammatory bowel disease (IBD). Only a few studies thus far have focused on UST pharmacokinetics suggesting that both, trough levels after i.v. induction as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ee2975beafae66d4f7431ad5a3bbd0c
https://doi.org/10.1093/ecco-jcc/jjab076.593
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5
Positive pharmacokinetic effect of azathioprine co-medication on infliximab trough levels is dose-dependent
Autor: Veronika Polakovicova, Katarina Otottova, Peter Mikuš, Kinova S, Barbora Kadleckova, Jana Lucenicova, Zuzana Zelinkova
Publikováno v: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 51(8)
Background Thiopurines seem to have positive effect on the pharmacokinetics of anti-tumor necrosis factor biologics. It has been suggested that a reduced dose of thiopurines is sufficient to achieve this synergism. Aims To assess the differences of i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e553c76dcf6ffbf6000069944f28e429
https://pubmed.ncbi.nlm.nih.gov/31147215
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6
P461 Vedolizumab Dose Escalation in a Real-World Cohort of IBD Patients
Autor: Jana Lucenicova, B Kadleckova, Zuzana Zelinkova
Publikováno v: Journal of Crohn's and Colitis. 15:S454-S454
Background Vedolizumab (VDZ) effectively induces and maintains remission in inflammatory bowel disease (IBD). The loss of response to VDZ has been shown to be recaptured with dose escalation but the data in this field are still scarce. In addition, d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41f748134315ff992461d15efecdf9ed
https://doi.org/10.1093/ecco-jcc/jjab076.584
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7
Analytical and Sample Preparation Protocol for Therapeutic Drug Monitoring of 12 Thiopurine Metabolites Related to Clinical Treatment of Inflammatory Bowel Disease
Autor: Peter Mikuš, Svetlana Dokupilová, Jana Lucenicova, Daniel Pecher, Maikel P. Peppelenbosch, Veronika Mikušová, Zuzana Zelinkova
Publikováno v: Molecules, Vol 23, Iss 7, p 1744 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Volume 23
Issue 7
Molecules, 23(7):1744. Multidisciplinary Digital Publishing Institute (MDPI)
Thiopurines (TP) represent an important therapeutic tool for the treatment of inflammatory bowel diseases (IBD) in the current situation of rising incidence and health care costs. The results of multiple clinical studies aimed at finding correlations
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65ff94d0a1c43c06cea7a3b762a889d
https://doi.org/10.3390/molecules23071744
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