Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jana Löwen"'
Publikováno v:
Nephrology Dialysis Transplantation.
This review summarizes the pathomorphological sequences of nephron loss in human diabetic nephropathy (DN). The relevant changes may be derived from two major derangements. First, a failure in the turnover of the glomerular basement membrane (GBM) ba
Autor:
Hermann-Josef Gröne, Jana Löwen, Felix Bestvater, Wilhelm Kriz, Marie-Luise Groß-Weißmann, Elisabeth F. Gröne
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F600-F616
Based on analysis of 819 human biopsies, essential derangement in diabetic nephropathy consists of accumulation of worn-out glomerular basement membrane in the mesangium that may advance to global sclerosis. The most frequent pathway to nephron dropo
Publikováno v:
American Journal of Physiology-Renal Physiology. 317:F399-F410
As shown in our previous paper (Kriz W, Löwen J, Federico G, van den Born J, Gröne E, Gröne HJ. Am J Physiol Renal Physiol 312: F1101–F1111, 2017), mesangial matrix expansion in diabetic nephropathy (DN) results for a major part from the accumul
Autor:
Jacob van den Born, Jana Löwen, Wilhelm Kriz, Elisabeth F. Gröne, Giuseppina Federico, Hermann Josef Gröne
Publikováno v:
American journal of physiology-Renal physiology, 312(6), F1101-F1111. AMER PHYSIOLOGICAL SOC
Thickening of the glomerular basement membrane (GBM) and expansion of the mesangial matrix are hallmarks of diabetic nephropathy (DN), generally considered to emerge from different sites of overproduction: GBM components from podocytes and mesangial