Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jana Löster"'
Publikováno v:
Scopus-Elsevier
In the course of analysis of ENU-induced mutations in Syrian hamsters, a novel dominant anophthalmic white mutant (WhV203) with hearing loss was recovered. Because of this phenotype and a close linkage to the Tpi gene, the Mitf gene was considered as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31b9d9849fcedff3076286ab181e2bc
https://doi.org/10.1093/genetics/164.3.1035
https://doi.org/10.1093/genetics/164.3.1035
Autor:
Jana Löster, Jochen Graw
Publikováno v:
Ophthalmic Genetics. 24:1-33
Much of our knowledge about the function of genes in mammalian development has been derived from the molecular analysis of spontaneous or induced mutations in the mouse. Since mutations affecting the mouse eye can be easily identified, a remarkable n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569064775c58477aed0ab246c8d8595a
https://doi.org/10.1076/opge.24.1.1.13888
https://doi.org/10.1076/opge.24.1.1.13888
Autor:
Cait E. MacPhee, Alan R. Prescott, Gijs F.J.M. Vrensen, Aileen Sandilands, Christopher M. Dobson, Shigeo Masaki, Raimund B. Lutz, Heather A. Long, A.M. Hutcheson, N Klopp, Jana Löster, Jochen Graw, Roy A. Quinlan
Publikováno v:
EMBO J. 21, 6005-6014 (2002)
Protein inclusions are associated with a diverse group of human diseases ranging from localized neurological disorders through to systemic non-neuropathic diseases. Here, we present evidence that the formation of intranuclear inclusions is a key even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6149081c1c97ddad7ad0ae45c6bb0251
https://doi.org/10.1093/emboj/cdf609
https://doi.org/10.1093/emboj/cdf609
Publikováno v:
Scopus-Elsevier
A novel ENU-induced mutation in the mouse leading to a nuclear and cortical opacity of the eye lens (ENU418) was mapped to proximal chromosome 1 by a genome-wide mapping approach. It suggests that the cluster of γ-crystallin encoding genes (Cryg) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6030e3bc20371f30cd73abbe66cbdd1
https://doi.org/10.1093/genetics/161.4.1633
https://doi.org/10.1093/genetics/161.4.1633
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Pax6 is a key regulator of eye development in vertebrates and invertebrates, and heterozygous loss-of-function mutations of the mouse Pax6 gene result in the Small eye phenotype, in which a small lens is a constant feature. To provide an understandin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9339e1095cacf82aa8223fba9007c253
https://doi.org/10.1073/pnas.132195699
https://doi.org/10.1073/pnas.132195699
Autor:
Eckhard Wolf, Helmut Fuchs, Dian Soewarto, André Reis, Martin Hrabé de Angelis, Rudi Balling, N Klopp, Johannes Becker-Follmann, Jana Löster, Jochen Graw
Publikováno v:
Scopus-Elsevier
ResearcherID
Genetics 157, 1313-1320 (2001)
Europe PubMed Central
ResearcherID
Genetics 157, 1313-1320 (2001)
Europe PubMed Central
A novel ENU-induced mutation in the mouse leading to a nuclear and zonular opacity of the eye lens (Aey1) was mapped to chromosome 1 between the markers D1Mit303 and D1Mit332. On the basis of the chromosomal position, the γ-crystallin encoding gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ea22ca7c294685cee8a5cd938e8bc5
https://doi.org/10.1093/genetics/157.3.1313
https://doi.org/10.1093/genetics/157.3.1313
Autor:
Jack Favor, Roy A. Quinlan, Angelika Neuhäuser-Klaus, Alan R. Prescott, N Klopp, Aileen Sandilands, Gijs F.J.M. Vrensen, Jana Löster, Raimund B. Lutz, Walter Pretsch, Jochen Graw
Publikováno v:
Genomics. 52:152-158
A number of murine cataract mutations have been localized to chromosome 1 close to the gamma-crystallin gene cluster (Cryg) (Everett et al., 1994, Genomics 20: 429-434; Loster et al., 1994, Genomics 23: 240-242). Based on the size of the mapping or a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9ebac085ed891b489f891b09078a2d
https://doi.org/10.1006/geno.1998.5417
https://doi.org/10.1006/geno.1998.5417
Autor:
Thomas Immervoll, Jochen Graw, Christina Grimm, Jack Favor, N Klopp, Bimal Chatterjee, Rodica Sandulache, Jana Löster
Publikováno v:
Developmental Genetics. 23:299-316
The homozygous mouse mutant aphakia (ak) has been characterized by bilaterally aphakic eyes without a pupil [Varnum DS, Stevens, LC (1968): J Hered 59:147-150]. The mutation was mapped to chromosome 19 [Varnum DS, Stevens, LC (1975): Mouse News Lett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fe38a80f3a5e060bee6857bafee4f94
https://doi.org/10.1002/(sici)1520-6408(1998)23:4<299::aid-dvg5>3.0.co
https://doi.org/10.1002/(sici)1520-6408(1998)23:4<299::aid-dvg5>3.0.co
Publikováno v:
Gene. 174:181-184
The cDNA sequence of the beta B2-cry was determined from hamster (Mesocricetus auratus) and compared to the corresponding genes of bovine, frog, chicken, human, mouse and rat. Multispecies comparison demonstrated high homology between the hamster, ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bb0838d4118d68ec8f145f718e5edc
https://doi.org/10.1016/0378-1119(96)00256-9
https://doi.org/10.1016/0378-1119(96)00256-9
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 233:795-800
• Background: From previous experiments it is known that the murine dominant cataract mutants carrying the gene Cat2 have a decreased content of γ-crystallin-specific transcripts in the juvenile lenses, when the cataract is completely expressed. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01dc5148c8e9028c2cab21c722aa0f3c
https://doi.org/10.1007/bf00184093
https://doi.org/10.1007/bf00184093