Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jana Krejci"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
For several decades the MCM2-7 proteins, the core of the DNA replicative helicase, eluded detection at DNA replication sites. Here, the authors solve this conundrum by gene editing, which enables visualization of replication dynamics in living cells.
Externí odkaz:
https://doaj.org/article/40546856371644f190ce151cd486b1df
Autor:
Kristian Brat, Monika Bratova, Jana Skrickova, Magda Barinova, Karolina Hurdalkova, Milos Pesek, Libor Havel, Leona Koubkova, Michal Hrnciarik, Jana Krejci, Ondrej Fischer, Milada Zemanova, Helena Coupkova, Martin Svaton
Publikováno v:
Thoracic Cancer, Vol 11, Iss 11, Pp 3346-3356 (2020)
Background Data regarding real‐life effectiveness of any treatment may improve clinical decision‐making. The aim of this study was to evaluate real‐life effectiveness of tyrosin‐kinase inhibitors, bevacizumab and pemetrexed as first‐line tr
Externí odkaz:
https://doaj.org/article/cbc351e845594ab6848729e0cc8a090b
Autor:
Miloslav, Marel, Zdenka, Chladkova, Luis Fernando, Casas Mendez, Ondrej, Venclicek, Jana, Skrickova, Ondej, Fischer, Andrea, Mullerova, Libor, Havel, Zuzana, Gyorfy, Michal, Hrnciarik, Michal, Jirousek, Jana, Krejci, Daniel, Krejci, Marcela, Buresova, Jana, Alahakoon, Michal, Svoboda, Martin, Svaton
Publikováno v:
Cancer Diagn Progn
Background/Aim: This study aimed at contributing to a better diagnosis of lung cancer by analyzing the patient’s symptoms and their linkage to other characteristics. Patients and Methods: We analyzed the data of 3,322 patients from LUCAS (LUngCAnce
Autor:
MARTIN SVATON, MONIKA BRATOVA, LEONA KOUBKOVA, ONDREJ FISCHER, BOHUSLAV MELICHAR, MICHAL HRNCIARIK, DANIEL DOLEZAL, ONDREJ BILEK, JANA KREJCI, MARIE DROSSLEROVA, ZDENKA DLOUHA, JIRI BLAZEK, PETRA MAJKOVA, LUCIE BROZOVA, MAREK STASTNY
Publikováno v:
Anticancer research. 42(4)
This study compared the results of nivolumab treatment in patients with pulmonary adenocarcinomas based upon previous chemotherapeutic regimens.The data source for this retrospective study was the Czech VILP registry of patients with nivolumab-treate
Autor:
Martin, Svaton, Monika, Bratova, Ondrej, Fischer, Jana, Krejci, Leona, Koubkova, Marketa, Cernovska, Michal, Hrnciarik, Milada, Zemanova, Helena, Coupkova, Bedrich, Porzer, Daniel, Dolezal, Tana, Tuzova, Karolina, Hurdalkova, Magda, Barinova, Jana, Skrickova
Publikováno v:
Anticancer research. 41(4)
We investigated efficacy differences for afatinib versus gefitinib in non-small-cell lung cancer (NSCLC) according to epidermal growth factor receptor (EGFR) mutations.We retrospectively analysed data for 343 patients with NSCLC with performance stat
Angiotensin-converting enzyme (ACE) is a zinc metalloproteinase involved in the renin-angiotensin system (RAS). It is well known that ACE and ACE2 are central regulators of blood pressure. Moreover, recently, it was observed that the ACE2 protein is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca976f2577e199690ecdf5f7685957bb
https://doi.org/10.21203/rs.3.rs-39062/v1
https://doi.org/10.21203/rs.3.rs-39062/v1
Autor:
Jana Krejčí
This book offers the first comprehensive and critical literature review of fuzzy pairwise comparison methods derived from methods originally developed for crisp pairwise comparison matrices. It proposes new fuzzy extensions of these methods and provi
Autor:
Miroslav Stibůrek, Petra Ondráčková, Tereza Tučková, Sergey Turtaev, Martin Šiler, Tomáš Pikálek, Petr Jákl, André Gomes, Jana Krejčí, Petra Kolbábková, Hana Uhlířová, Tomáš Čižmár
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Controlled light transport through multimode fibres has recently emerged as uniquely atraumatic prospect to study deep brain structures. Here, authors present hair-thin endoscope providing detailed view through the whole depth of living animal brain.
Externí odkaz:
https://doaj.org/article/d2a48eb34d0846fb872622dc10ad6e64
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8139 (2020)
It has become evident that epitranscriptome events, mediated by specific enzymes, regulate gene expression and, subsequently, cell differentiation processes. We show that methyltransferase-like proteins METTL3/METTL14 and N6-adenosine methylation (m6
Externí odkaz:
https://doaj.org/article/40561e7a8dff46c389c81ce3f997e160
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Cajal bodies (CBs) are important compartments containing accumulated proteins that preferentially regulate RNA-related nuclear events, including splicing. Here, we studied the nuclear distribution pattern of CBs in neurogenesis. In adult brains, coil
Externí odkaz:
https://doaj.org/article/41cca016a8704c4c87b0e85176677703