Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jana I, Solomun"'
Autor:
Jana I. Solomun, Liam Martin, Prosper Mapfumo, Elisabeth Moek, Elias Amro, Friedrich Becker, Stefan Tuempel, Stephanie Hoeppener, K. Lenhard Rudolph, Anja Traeger
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Cationic non-viral vectors show great potential to introduce genetic material into cells, due to their ability to transport large amounts of genetic material and their high synthetic versatility. However, designing materials that are effecti
Externí odkaz:
https://doaj.org/article/ac8763d1ebac4c56bbc35c6a64eaf456
Autor:
Friederike Richter, Katharina Leer, Liam Martin, Prosper Mapfumo, Jana I. Solomun, Maren T. Kuchenbrod, Stephanie Hoeppener, Johannes C. Brendel, Anja Traeger
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Cationic polymers have been widely studied for non-viral gene delivery due to their ability to bind genetic material and to interact with cellular membranes. However, their charged nature carries the risk of increased cytotoxicity and intera
Externí odkaz:
https://doaj.org/article/37aac02f5cbe403ab2958fea85a9a46d
Autor:
Friederike Richter, Prosper Mapfumo, Liam Martin, Jana I. Solomun, Franziska Hausig, Jochen J. Frietsch, Thomas Ernst, Stephanie Hoeppener, Johannes C. Brendel, Anja Traeger
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Although there has been substantial progress in the research field of gene delivery, there are some challenges remaining, e.g. there are still cell types such as primary cells and suspension cells (immune cells) known to be difficult to tran
Externí odkaz:
https://doaj.org/article/83f2b0a9f25f47e8b38855a8890e319d
Autor:
Franziska Hausig‐Punke, Gregor Dekevic, Fabian H. Sobotta, Jana I. Solomun, Friederike Richter, Denise Salzig, Anja Traeger, Johannes C. Brendel
Publikováno v:
Macromolecular Bioscience. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fa987b3e1c990cd0af31f3f3c81f77
https://doi.org/10.1002/mabi.202370016
https://doi.org/10.1002/mabi.202370016
Autor:
Paul Klemm, Jana I. Solomun, Marko Rodewald, Maren T. Kuchenbrod, Veit G. Hänsch, Friederike Richter, Jürgen Popp, Christian Hertweck, Stephanie Hoeppener, Colin Bonduelle, Sébastien Lecommandoux, Anja Traeger, Stephanie Schubert
Publikováno v:
Biomacromolecules. 23(11)
Within this study, an amphiphilic and potentially biodegradable polypeptide library based on poly[(4-aminobutyl)-l-glutamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30428b8dc1fd4f10b0d97d19938858a
https://pubmed.ncbi.nlm.nih.gov/36269943
https://pubmed.ncbi.nlm.nih.gov/36269943
Publikováno v:
Nanoscale. 13:19412-19429
Stimuli-responsive block copolymer micelles can provide tailored properties for the efficient delivery of genetic material. In particular, temperature- and pH-responsive materials are of interest, since their physicochemical properties can be easily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b384511a012d4e3e1b89ac5b8eaa6e3
https://doi.org/10.1039/d1nr04223h
https://doi.org/10.1039/d1nr04223h
Publikováno v:
Analytica chimica acta. 1205
Hydrodynamic and light scattering methods are urgently required for accurate characterization of nanoparticles (NPs) in the field of nanomedicine to unveil their sizes and distributions. A fundamental characterization approach in the field of nanomed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec992987adb4baf75e6d0654eaa8476
https://pubmed.ncbi.nlm.nih.gov/35414386
https://pubmed.ncbi.nlm.nih.gov/35414386
Autor:
Jana I. Solomun, Anja Traeger, Paul Klemm, Colin Bonduelle, Mira Behnke, Stephanie Schubert, Sébastien Lecommandoux
Publikováno v:
Journal of materials chemistry B
Journal of materials chemistry B, Royal Society of Chemistry, 2021, 9 (39), pp.8224-8236. ⟨10.1039/d1tb01495a⟩
Journal of materials chemistry B, Royal Society of Chemistry, 2021, 9 (39), pp.8224-8236. ⟨10.1039/d1tb01495a⟩
International audience; In the present study, three biodegradable block copolymers composed of a poly(ethylene glycol) block and a copolypeptide block with varying compositions of cationic L-lysine (L-Lys) and hydrophobic benzyl-L-glutamate (Bzl-L-Gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4ee73ab282f2c0d95b63d2bf01a002
https://hal.archives-ouvertes.fr/hal-03452272
https://hal.archives-ouvertes.fr/hal-03452272
Autor:
Jana I, Solomun, Liam, Martin, Prosper, Mapfumo, Elisabeth, Moek, Elias, Amro, Friedrich, Becker, Stefan, Tuempel, Stephanie, Hoeppener, K Lenhard, Rudolph, Anja, Traeger
Publikováno v:
Journal of nanobiotechnology. 20(1)
Cationic non-viral vectors show great potential to introduce genetic material into cells, due to their ability to transport large amounts of genetic material and their high synthetic versatility. However, designing materials that are effective withou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d2316c8b9dc9833b86c2eb89a890e6f
https://pubmed.ncbi.nlm.nih.gov/35842657
https://pubmed.ncbi.nlm.nih.gov/35842657
Autor:
Friederike Richter, Ivo Nischang, Anja Traeger, Prosper Mapfumo, Gizem Cinar, Franziska Hausig, Liam Martin, Stephanie Hoeppener, Elisabeth Moek, Jana I. Solomun
Publikováno v:
International journal of pharmaceutics. 593
Cationic polymers are promising gene delivery vectors due to their ability to bind and protect genetic material. The introduction of hydrophobic moieties into cationic polymers can further improve the vector efficiency, but common formulations of hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62f9e1cccdb8eb48ea418fc7510fea9
https://pubmed.ncbi.nlm.nih.gov/33246046
https://pubmed.ncbi.nlm.nih.gov/33246046