Hydrodynamic trapping measures the interaction between membrane-associated molecules

Autor: Ana Filipa L.O.M. Santos, Jana Hladilkova, Peter Jönsson, Victoria Junghans, Simon J. Davis, Mikael Lund

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports

How membrane proteins distribute and behave on the surface of cells is determined by the molecules’ interaction potential. However, measuring this potential, and how it varies with protein-to-protein distance, has been challenging. We here present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860e18ef562fc272419ef2fb230d837d
http://link.springer.com/article/10.1038/s41598-018-30285-0

Binding of Divalent Cations to Insulin: Capillary Electrophoresis and Molecular Simulations

Autor: Hector Martinez-Seara, Jana Hladilkova, Elise Duboué-Dijon, Pavel Coufal, Pauline Delcroix, Tomáš Křížek, Pavel Jungwirth

Publikováno v: Journal of Physical Chemistry B
Journal of Physical Chemistry B, American Chemical Society, 2018, 122 (21), pp.5640-5648. ⟨10.1021/acs.jpcb.7b12097⟩

International audience; In the present study, we characterize the binding of divalent cations to insulin in aqueous salt solutions by means of capillary electrophoresis and molecular dynamics simulations. The results show a strong pH dependence. At l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650f2095b07eb74881622e5e4a95bf36
https://hal.archives-ouvertes.fr/hal-02309470