Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jana Hennesen"'
Autor:
Benjamin Grünhagel, Malte Borggrewe, Sven Hendrik Hagen, Susanne M. Ziegler, Florian Henseling, Laura Glau, Rebecca-Jo Thiele, Maria Pujantell, Varshi Sivayoganathan, Benedetta Padoan, Janna M. Claussen, Arne Düsedau, Jana Hennesen, Madeleine J. Bunders, Stefan Bonn, Eva Tolosa, Christian F. Krebs, Christoph Dorn, Marcus Altfeld
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108209- (2023)
Summary: Type I interferons (IFN-I) are important mediators of antiviral immunity and autoimmune diseases. Female plasmacytoid dendritic cells (pDCs) exert an elevated capacity to produce IFN-I upon toll-like receptor 7 (TLR7) activation compared to
Externí odkaz:
https://doaj.org/article/3e9659bff4ad40d09be5365c3478f73a
Autor:
Annerose E. Ziegler, Pia Fittje, Luisa M. Müller, Annika E. Ahrenstorf, Kerri Hagemann, Sven H. Hagen, Leonard U. Hess, Annika Niehrs, Tobias Poch, Gevitha Ravichandran, Sebastian M. Löbl, Benedetta Padoan, Sébastien Brias, Jana Hennesen, Myrtille Richard, Laura Richert, Sven Peine, Karl J. Oldhafer, Lutz Fischer, Christoph Schramm, Glòria Martrus, Madeleine J. Bunders, Marcus Altfeld, Sebastian Lunemann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The crosstalk between NK cells and their surrounding environment is enabled through activating and inhibitory receptors, which tightly control NK cell activity. The co-inhibitory receptor TIGIT decreases NK cell cytotoxicity and is involved in NK cel
Externí odkaz:
https://doaj.org/article/8eaeca7d25fc4207b64b0945cfe316a2
Assessment of escape from X chromosome inactivation and gene expression in single human immune cells
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100641- (2021)
Summary: X-chromosomal genes escaping from X chromosome inactivation (XCI) in immune cells can contribute to sex-specific differences in immune responses. This protocol describes the specific steps to determine escape from XCI and to simultaneously q
Externí odkaz:
https://doaj.org/article/1ca386d1b8914d5e904e8eb959b8a2ef
Autor:
Sven Hendrik, Hagen, Florian, Henseling, Jana, Hennesen, Hélène, Savel, Solenne, Delahaye, Laura, Richert, Susanne Maria, Ziegler, Marcus, Altfeld
Publikováno v:
Cell Reports
Immune responses differ between women and men, and type I interferon (IFN) responses following Toll-like receptor 7 (TLR7) stimulation are higher in women. The precise mechanisms driving these sex differences in immunity are unknown. To investigate p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8b90f4f47487fa87a5618ba4ddcfece
https://pubmed.ncbi.nlm.nih.gov/33296655
https://pubmed.ncbi.nlm.nih.gov/33296655
Assessment of escape from X chromosome inactivation and gene expression in single human immune cells
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 3, Pp 100641-(2021)
STAR Protocols, Vol 2, Iss 3, Pp 100641-(2021)
Summary X-chromosomal genes escaping from X chromosome inactivation (XCI) in immune cells can contribute to sex-specific differences in immune responses. This protocol describes the specific steps to determine escape from XCI and to simultaneously qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adddc86a3d3f7bcd347dacf1da9e2595
https://doi.org/10.1016/j.xpro.2021.100641
https://doi.org/10.1016/j.xpro.2021.100641
Publikováno v:
Apoptosis. 15:162-172
The topoisomerase IIalpha inhibitor etoposide is a 'broad spectrum' anticancer agent and a potent inducer of DNA double strand breaks. DNA damage response of mammalian cells usually involves cell cycle arrest and DNA repair or, if unsuccessful, cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dd4579f6436fb64ac8a73ef1b6de5c
https://doi.org/10.1007/s10495-009-0440-9
https://doi.org/10.1007/s10495-009-0440-9
Publikováno v:
Apoptosis : an international journal on programmed cell death. 16(4)
For DNA targeting anticancer drugs, cellular DNA repair mechanisms may cause resistance and hamper the therapeutic outcome. DNA damage induced by topoisomerase IIα inhibitors like etoposide and anthracyclines, which are a mainstay of cancer therapy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47b40d63df223905f6495548c87fe7b
https://pubmed.ncbi.nlm.nih.gov/21107697
https://pubmed.ncbi.nlm.nih.gov/21107697