Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jana Heigwer"'
Autor:
Jens H. Westhoff, Petrus J. Steenbergen, Laurent S. V. Thomas, Jana Heigwer, Thomas Bruckner, Ledean Cooper, Burkhard Tönshoff, Georg F. Hoffmann, Jochen Gehrig
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Despite widespread drug exposure, for example during gestation or in prematurely born children, organ-specific developmental toxicity of most drugs is poorly understood. Developmental and functional abnormalities are a major cause of kidney diseases
Externí odkaz:
https://doaj.org/article/0fe8e17202554fb7bf3447870d4c3a9a
Autor:
Petrus J. Steenbergen, Jana Heigwer, Gunjan Pandey, Burkhard Tönshoff, Jochen Gehrig, Jens H. Westhoff
Publikováno v:
Cells, Vol 9, Iss 5, p 1269 (2020)
Automated high-throughput workflows allow for chemical toxicity testing and drug discovery in zebrafish disease models. Due to its conserved structural and functional properties, the zebrafish pronephros offers a unique model to study renal developme
Externí odkaz:
https://doaj.org/article/b5707b8f21e84edca8bd592761bdf83e
Autor:
Damir Krunic, Felix Bestvater, Michael Hausmann, Jens H Westhoff, Jana Heigwer, Sotirios G. Zarogiannis, David Ridinger, Stefan Terjung, Iva Marinovic, Claus Peter Schmitt, Georg Hildenbrand, Eszter Levai, Conghui Zhang, Franz Schaefer, Maria Bartosova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8178, p 8178 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences
Volume 22
Issue 15
Endothelial and epithelial barrier function is crucial for the maintenance of physiological processes. The barrier paracellular permeability depends on the composition and spatial distribution of the cell-to-cell tight junctions (TJ). Here, we provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4dd63422a3220f59a58284eae52979
https://www.mdpi.com/1422-0067/22/15/8178
https://www.mdpi.com/1422-0067/22/15/8178
Autor:
Jana Heigwer, Jens H. Westhoff, Petrus J. Steenbergen, Jochen Gehrig, Gunjan Pandey, Burkhard Tönshoff
Publikováno v:
Cells
Volume 9
Issue 5
Cells, Vol 9, Iss 1269, p 1269 (2020)
Volume 9
Issue 5
Cells, Vol 9, Iss 1269, p 1269 (2020)
Automated high-throughput workflows allow for chemical toxicity testing and drug discovery in zebrafish disease models. Due to its conserved structural and functional properties, the zebrafish pronephros offers a unique model to study renal developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57e64d4be18a17194a73c5b64b576ac
Autor:
Georg F. Hoffmann, Jochen Gehrig, Burkhard Toenshoff, Laurent S. V. Thomas, Jana Heigwer, Thomas Bruckner, Ledean Cooper, Petrus J. Steenbergen, Jens H. Westhoff
Publikováno v:
Frontiers in Cell and Developmental Biology
Despite widespread drug exposure, for example during gestation or in prematurely born children, organ-specific developmental toxicity of most drugs is poorly understood. Developmental and functional abnormalities are a major cause of kidney diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2bf5c492a40084958d1f15a45ad37c
https://doi.org/10.1101/2020.04.21.052688
https://doi.org/10.1101/2020.04.21.052688
Autor:
David Hassel, Lonny Juergensen, Thomas Draebing, Melanie Philipp, Hugo A. Katus, Monika Haeussler, Jana Heigwer, Jens H. Westhoff, Martin D. Burkhalter, Juliane Kutzner
Publikováno v:
Biochemical and biophysical research communications. 527(2)
In zebrafish, cilia movement within the Kupffer's vesicle (KV) generates a fluid flow responsible for accumulating nodal signals exclusively in the left lateral plate mesoderm, thereby initiating left-right patterning (LRP). Defects in LRP cause deva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2d25fa791683d9779f3cef90da11f9
https://pubmed.ncbi.nlm.nih.gov/32334837
https://pubmed.ncbi.nlm.nih.gov/32334837
Morphogens including Wnt, Hedgehog and BMP proteins are essential during embryonic development and early induction of organ progenitors. Besides free diffusion to form signalling gradients, extracellular vesicle- (EV-) mediated morphogen transport wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a908ff56890d80cfab82f56a5a429b2
https://doi.org/10.1101/321356
https://doi.org/10.1101/321356
Publikováno v:
Developmental biology. 383(2)
Cardiovascular disease is a global scourge to society, with novel therapeutic approaches required in order to alleviate the suffering caused by sustained cardiac damage. MicroRNAs (miRNAs) are being touted as one such approach in the fight against he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3312f7caa21824f788ad5380989fd5
https://pubmed.ncbi.nlm.nih.gov/24055866
https://pubmed.ncbi.nlm.nih.gov/24055866