Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jana Havrankova"'
Autor:
Federico, Colombo, Paolo, Durigutto, Luca, De Maso, Stefania, Biffi, Beatrice, Belmonte, Claudio, Tripodo, Romina, Oliva, Paola, Bardini, Giada M, Marini, Enzo, Terreno, Gabriele, Pozzato, Enrico, Rampazzo, Jessica, Bertrand, Bernd, Feuerstein, Jakub, Javurek, Jana, Havrankova, Costantino, Pitzalis, Luis, Nuñez, Pierluigi, Meroni, Francesco, Tedesco, Daniele, Sblattero, Paolo, Macor
Publikováno v:
Journal of autoimmunity. 103
Despite the advances in the treatment of rheumatoid arthritis (RA) achieved in the last few years, several patients are diagnosed late, do not respond to or have to stop therapy because of inefficacy and/or toxicity, leaving still a huge unmet need.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::329a48289d1342eecb05658e860fe2be
https://pubmed.ncbi.nlm.nih.gov/31213399
https://pubmed.ncbi.nlm.nih.gov/31213399
Autor:
Jana Havrankova, Luis Nunez, Enrico Rampazzo, Enzo Terreno, Jakub Javurek, Romina Oliva, Costantino Pitzalis, Beatrice Belmonte, Claudio Tripodo, Stefania Biffi, Paola Bardini, Pier Luigi Meroni, Bernd Feuerstein, Gabriele Pozzato, Jessica Bertrand, Giada Maria Marini, Federico Colombo, Luca De Maso, Paolo Macor, Daniele Sblattero, Paolo Durigutto, Francesco Tedesco
Despite the advances in the treatment of rheumatoid arthritis (RA) achieved in the last few years, several patients are diagnosed late, do not respond to or have to stop therapy because of inefficacy and/or toxicity, leaving still a huge unmet need.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a835458fd5d5b0dd5900e93b632834
http://hdl.handle.net/2318/1730799
http://hdl.handle.net/2318/1730799
Autor:
Hana Štambergová, Lucie Zemanová, Jana Havrankova, Miroslav Šafr, Tereza Lundová, Markéta Preininger Svobodová, Vladimír Wsól
Publikováno v:
Molecular and Cellular Biochemistry. 411:35-42
Dehydrogenase/reductase (SDR family) member 8 (DHRS8, SDR16C2) belongs to the short-chain dehydrogenase/reductase (SDR) superfamily, one of the largest enzyme groups. In addition to the well-known members which participate in the metabolism of import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ed8d41c850bf1727e40a41987755e9
https://doi.org/10.1007/s11010-015-2566-0
https://doi.org/10.1007/s11010-015-2566-0
Publikováno v:
Biochemical Pharmacology. 96:168-178
Paclitaxel (PTX), docetaxel (DTX), 5-fluorouracil (5-FU), cyclophosphamide (CYC) or tamoxifen (TMX) are combined with doxorubicin (DOX) in first-line chemotherapy regimens that are indicated for breast cancer patients. Although the efficacies of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35174b6c2937b141560b83cfb312da3c
https://doi.org/10.1016/j.bcp.2015.05.005
https://doi.org/10.1016/j.bcp.2015.05.005
Autor:
Adam Skarka, Lucie Zemanová, Miroslav Šafr, Hana Štambergová, Beata Malčeková, Vladimír Wsól, Jana Havrankova, Tereza Lundová
Publikováno v:
Chemico-Biological Interactions. 234:178-187
Dehydrogenase/reductase (SDR family) member 3 (DHRS3), also known as retinal short-chain dehydrogenase/reductase (retSDR1) is a member of SDR16C family. This family is thought to be NADP(H) dependent and to have multiple substrates; however, to date,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4321f6ec6545a296cd7e0726e1206fe0
https://doi.org/10.1016/j.cbi.2014.10.018
https://doi.org/10.1016/j.cbi.2014.10.018
Autor:
Jakub Hofman, Tomas Plucha, Adam Skarka, Lucie Skarydova, Jana Havrankova, Jakub Chlebek, Katerina Kosanova, Anna Hošt'álková, Vladimír Wsól, Lucie Cahlíková
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 143:250-258
AKR1C3 is an important human enzyme that participates in the reduction of steroids and prostaglandins, which leads to proliferative signalling. In addition, this enzyme also participates in the biotransformation of xenobiotics, such as drugs and proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec5fb75dd182f19a7d611ff551f49a4
https://doi.org/10.1016/j.jsbmb.2014.04.005
https://doi.org/10.1016/j.jsbmb.2014.04.005
Publikováno v:
Diabetologia. 20(Suppl 1)
While insulin effects on the central nervous system (CNS) mediated through hypoglycaemia are well known, direct insulin effects on the CNS remain controversial. Recently, we found insulin receptors in all areas of the rat brain, with highest concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad36593dac7bfea68463087623656cef
https://pubmed.ncbi.nlm.nih.gov/27942811
https://pubmed.ncbi.nlm.nih.gov/27942811
Autor:
Eva Novotná, Tereza Lundová, Anna Hošt'álková, Jakub Hofman, Jana Havrankova, Lucie Zemanová, Jakub Chlebek, Lucie Cahlíková, Kamil Musilek, Vladimír Wsól
Publikováno v:
Journal of natural products. 78(11)
AKR1B10 is an NADPH-dependent reductase that plays an important function in several physiological reactions such as the conversion of retinal to retinol, reduction of isoprenyl aldehydes, and biotransformation of procarcinogens and drugs. A growing b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a8e04d3e5ea6a517e4263b949505db
https://pubmed.ncbi.nlm.nih.gov/26529431
https://pubmed.ncbi.nlm.nih.gov/26529431
Publikováno v:
Diabetes. 42:35-43
Vitamin D is essential for normal insulin secretion in vivo and in vitro. The differential effect of calcium and of the vitamin D endocrine system in the insulin response to secretagogues is still a subject of debate. To study the roles of calcium an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef1a3ee0937cb9d2a5be47321c69db5
https://doi.org/10.2337/diabetes.42.1.35
https://doi.org/10.2337/diabetes.42.1.35