Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jana Házová"'
Autor:
Klara Horackova, Petra Zemankova, Petr Nehasil, Michal Vocka, Milena Hovhannisyan, Katerina Matejkova, Marketa Janatova, Marta Cerna, Petra Kleiblova, Sandra Jelinkova, Barbora Stastna, Pavel Just, Tatana Dolezalova, Barbora Nemcova, Marketa Urbanova, Monika Koudova, Jana Hazova, Eva Machackova, Lenka Foretova, Viktor Stranecky, Michal Zikan, Zdenek Kleibl, Jana Soukupova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The subset of ovarian cancer (OC) diagnosed ≤ 30yo represents a distinct subgroup exhibiting disparities from late-onset OC in many aspects, including indefinite germline cancer predisposition. We performed DNA/RNA-WES with HLA-typing, PRS
Externí odkaz:
https://doaj.org/article/ad5550950aed42c6b56e4a609805f4e6
Autor:
Eva Macháčková, Marek Svoboda, Marie Navratilova, Eva Hrabincová Sťahlová, Jana Házová, Pavel Fabian, Petra Vašíčková, Lenka Foretová, Monika Schneiderová
Publikováno v:
Klinicka Onkologie. 32
Background BAP1 syndrome is an autosomal dominant hereditary cancer syndrome associated with increased risk of malignant mesothelioma; uveal and cutaneous melanoma; kidney cancer; lung adenocarcinoma; meningioma; basaliomas; and breast, ovarian, and
Autor:
Petra Vašíčková, Miroslava Mikova, Eva Macháčková, Lenka Foretová, Jana Házová, Marek Svoboda, Kathleen Claes, Martin Trbusek, Eva Hrabincová Sťahlová, Marie Navratilova
Publikováno v:
KLINICKÁ ONKOLOGIE
BACKGROUND Deleterious mutations in the BRCA1 and BRCA2 genes account for a considerable proportion of dominantly inherited breast and ovarian cancer susceptibility. The laboratory interpretation has always been dependent on the information available
Autor:
Eva Hrabincová Sťahlová, Eva Macháčková, Petra Vašíčková, Jana Házová, Markéta Palácová, Katarína Petráková, Petra Kleiblova, Zdeněk Kleibl, Marie Navratilova, Marek Svoboda, Lenka Foretová
Publikováno v:
Klinicka Onkologie. 32
An inherited predisposition to breast cancer underlies 5-10% of breast tumors. High-risk BRCA1 and BRCA2 genes result in an 85% lifetime risk of breast cancer and a 20-60% lifetime risk of ovarian cancer. Next-generation sequencing or massive paralle
Autor:
Petra Vašíčková, Marek Svoboda, Pavel Fabian, Petr Grell, Eva Macháčková, Lenka Foretová, Radek Kroupa, Lukáš Sirotek, Libor Nemec, Jana Házová, Eva Hrabincová Sťahlová, Milana Šachlová, Ivo Novotný, Marie Navratilova, Radka Obermannova
Publikováno v:
Klinicka Onkologie. 32
Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) is a rare variant of familial adenomatous polyposis. It is an autosomal-dominant cancer-predisposition syndrome with massive polyposis of the stomach and a significant risk of gastr
Retrospective NGS Study in High-risk Hereditary Cancer Patients at Masaryk Memorial Cancer Institute
Autor:
Vašíčková P, Foretová L, Jana Házová, Marie Navratilova, Marek Svoboda, Sťahlová Hrabincová E, Eva Macháčková
Publikováno v:
Klinicka onkologie. 29:S35-S45
Background Currently, more than 200 hereditary cancer syndromes have been described, yet, in most countries genetic testing is restricted to a narrow spectrum of genes within a limited group of people tested. Methods For this retrospective study we u