Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jana Frydlova"'
Autor:
Jana Frydlova, Iveta Zednikova, Veronika Satrapova, Eva Pazourkova, Sarka Santorova, Zdenka Hruskova, Vladimir Tesar, Martin Vokurka, Petr Prikryl, Marie Korabecna
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4344 (2022)
Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) represents an autoimmunity disease characterized by high mortality. For successful treatment, the detailed knowledge of its complex pathogenesis and the set of biomarkers for di
Externí odkaz:
https://doaj.org/article/3e8329ac1b2040bf9e95499fdc7484ae
Autor:
Martin Vokurka, Tomáš Zima, Petr Prikryl, Vladimir Tesar, Veronika Satrapova, Jana Frydlova, Zdenka Hruskova
Publikováno v:
Journal of Proteomics. 233:104067
ANCA-associated vasculitis (AAV) is a rare, but potentially severe autoimmune disease, even nowadays displaying increased mortality and morbidity. Finding early biomarkers of activity and prognosis is thus very important. Small extracellular vesicles
Publikováno v:
Current Opinion in Biotechnology. 24:S111-S112
Publikováno v:
Current Opinion in Biotechnology. 24:S64
Autor:
Betty Berezovsky, Jana Frýdlová, Iuliia Gurieva, Daniel W. Rogalsky, Martin Vokurka, Jan Krijt
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5899 (2022)
The purpose of the study was to investigate the expression of ferroportin protein following treatments that affect systemic hepcidin. Administration of erythropoietin to C57BL/6J mice decreased systemic hepcidin expression; it also increased heart fe
Externí odkaz:
https://doaj.org/article/aade612d0903448a9e8ddc48e6b0f5b0
Autor:
Betty Berezovsky, Martin Báječný, Jana Frýdlová, Iuliia Gurieva, Daniel Wayne Rogalsky, Petr Přikryl, Vít Pospíšil, Emanuel Nečas, Martin Vokurka, Jan Krijt
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8209 (2021)
Erythropoietin (EPO) downregulates hepcidin expression to increase the availability of iron; the downregulation of hepcidin is mediated by erythroferrone (ERFE) secreted by erythroblasts. Erythroblasts also express transferrin receptor 2 (TFR2); howe
Externí odkaz:
https://doaj.org/article/572a3dd4dd8340ccafce2a1d128a5e36
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215028 (2019)
Expression of hepcidin, the hormone regulating iron homeostasis, is increased by iron overload and decreased by accelerated erythropoiesis or iron deficiency. The purpose of the study was to examine the effect of these stimuli, either alone or in com
Externí odkaz:
https://doaj.org/article/41d652ffd7c84526973f3968bbdb36df
Autor:
Jan Krijt, Jana Frýdlová, Iuliia Gurieva, Petr Přikryl, Martin Báječný, Andrea U. Steinbicker, Martin Vokurka, Jaroslav Truksa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2650 (2021)
Matriptase-2, a serine protease expressed in hepatocytes, is a negative regulator of hepcidin expression. The purpose of the study was to investigate the interaction of matriptase-2 with hemojuvelin protein in vivo. Mice lacking the matriptase-2 prot
Externí odkaz:
https://doaj.org/article/0b7d040815df4f9b80b8dcf244771ec5
Autor:
Jana Frýdlová, Zuzana Rychtarčíková, Iuliia Gurieva, Martin Vokurka, Jaroslav Truksa, Jan Krijt
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186844 (2017)
Tmprss6-mutated mask mice display iron deficiency anemia and high expression of hepcidin. The aim of the study was to determine the effect of erythropoietin administration on proteins participating in the control of iron homeostasis in the liver and
Externí odkaz:
https://doaj.org/article/cdea54ec9fe14973bd0c5ad5b4418b04
Autor:
Jana Frýdlová, Petr Přikryl, Jaroslav Truksa, Lucas L Falke, Xin Du, Iuliia Gurieva, Martin Vokurka, Jan Krijt
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148540 (2016)
Matriptase-2 (TMPRSS6) is an important negative regulator of hepcidin expression; however, the effects of iron overload or accelerated erythropoiesis on liver TMPRSS6 protein content in vivo are largely unknown. We determined TMPRSS6 protein content
Externí odkaz:
https://doaj.org/article/565129c3e11a464893851c46bafd3f6d