Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jana F Liewald"'
Autor:
Amelie Bergs, Christian Schultheis, Elisabeth Fischer, Satoshi P Tsunoda, Karen Erbguth, Steven J Husson, Elena Govorunova, John L Spudich, Georg Nagel, Alexander Gottschalk, Jana F Liewald
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191802 (2018)
In optogenetics, rhodopsins were established as light-driven tools to manipulate neuronal activity. However, during long-term photostimulation using channelrhodopsin (ChR), desensitization can reduce effects. Furthermore, requirement for continuous p
Externí odkaz:
https://doaj.org/article/8ba053d63cc847a48c2fe36a55bc581c
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110687- (2024)
Summary: Chemical synaptic transmission is modulated to accommodate different activity levels, thus enabling homeostatic scaling in pre- and postsynaptic compartments. In nematodes, cholinergic neurons use neuropeptide signaling to modulate synaptic
Externí odkaz:
https://doaj.org/article/8a9822cab6a544b396e05fc3fadc6fc8
Autor:
Steven J Husson, Jana F Liewald, Christian Schultheis, Jeffrey N Stirman, Hang Lu, Alexander Gottschalk
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40937 (2012)
Essentially any behavior in simple and complex animals depends on neuronal network function. Currently, the best-defined system to study neuronal circuits is the nematode Caenorhabditis elegans, as the connectivity of its 302 neurons is exactly known
Externí odkaz:
https://doaj.org/article/f08e4009a5b3443088f8b601ae8c934c
Autor:
Cornelia Schmitt, Christian Schultheis, Navin Pokala, Steven J Husson, Jana F Liewald, Cornelia I Bargmann, Alexander Gottschalk
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43164 (2012)
Optogenetic approaches using light-activated proteins like Channelrhodopsin-2 (ChR2) enable investigating the function of populations of neurons in live Caenorhabditis elegans (and other) animals, as ChR2 expression can be targeted to these cells usi
Externí odkaz:
https://doaj.org/article/3695ae93f0194176b4ab75b4dfc9dca8
Autor:
Amelie C. F. Bergs, Jana F. Liewald, Silvia Rodriguez-Rozada, Qiang Liu, Christin Wirt, Artur Bessel, Nadja Zeitzschel, Hilal Durmaz, Adrianna Nozownik, Holger Dill, Maëlle Jospin, Johannes Vierock, Cornelia I. Bargmann, Peter Hegemann, J. Simon Wiegert, Alexander Gottschalk
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Optogenetic actuation regimes are often static, which allows perturbation, but not true control of neuronal activity. Here, the authors describe an all-optical method for bidirectional steering of membrane potential, in closed loop, in C. elegans mus
Externí odkaz:
https://doaj.org/article/4373263f0a2a4c2cbd268fdc4a4ba5a6
Autor:
Amelie C.F. Bergs, Jana F. Liewald, Silvia Rodriguez-Rozada, Qiang Liu, Christin Wirt, Artur Bessel, Nadja Zeitzschel, Hilal Durmaz, Adrianna Nozownik, Maëlle Jospin, Johannes Vierock, Cornelia I. Bargmann, Peter Hegemann, J. Simon Wiegert, Alexander Gottschalk
Excitable cells can be stimulated or inhibited by optogenetics. Since optogenetic actuation regimes are often static, neurons and circuits can quickly adapt, allowing perturbation, but not true control. Hence, we established an optogenetic voltage-cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff6262b53a80cb3c8943ba8a7f1c3e0
https://doi.org/10.1101/2022.06.03.494532
https://doi.org/10.1101/2022.06.03.494532
Autor:
Thilo Henss, Martin Schneider, Dennis Vettkötter, Wagner Steuer Costa, Jana F. Liewald, Alexander Gottschalk
Publikováno v:
cAMP Signaling ISBN: 9781071622445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d92ec08ff9ff9d360f91264e09e2a29
https://doi.org/10.1007/978-1-0716-2245-2_4
https://doi.org/10.1007/978-1-0716-2245-2_4
Autor:
Bergs Acf, Wagner Steuer Costa, Jana F. Liewald, Alexander Gottschalk, Azimi Hashemi N, Christina Schüler, Bach M, Scheiwe Ar
Publikováno v:
Proceedings of the National Academy of Sciences. 116:17051-17060
Genetically encoded voltage indicators (GEVIs) based on microbial rhodopsins utilize the voltage-sensitive fluorescence of all- trans retinal (ATR), while in electrochromic FRET (eFRET) sensors, donor fluorescence drops when the rhodopsin acts as dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::275105c4d320a4ae1ed0ce58777d69b1
https://doi.org/10.1073/pnas.1902443116
https://doi.org/10.1073/pnas.1902443116
Publikováno v:
BIOspektrum. 25:398-401
In rhodopsin-based optogenetics the light-activatable cation channel ChR2 is employed to selectively gain control over single neurons. As arising experimental questions become more and more challenging, there is a strong need to further expand the op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82abd635bef0502cb49cd0858ac4d6b8
https://doi.org/10.1007/s12268-019-1069-z
https://doi.org/10.1007/s12268-019-1069-z
Autor:
Jánosi B, Szi-chieh Yu, Jana F. Liewald, Alexander Gottschalk, Amelie C. F. Bergs, Jiajie Shao, Umbach S, Martin W. Schneider, Alcantara Ic
Synapses are intricately organized subcellular compartments in which molecular machines cooperate to ensure spatiotemporally precise transmission of chemical signals. Key components of this machinery are voltage-gated Ca2+-channels (VGCCs), that tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f85cc6cc08d2b4cd8cc271f0e46f599
https://doi.org/10.1101/2021.02.01.429206
https://doi.org/10.1101/2021.02.01.429206