Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jana F, Liewald"'
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110687- (2024)
Summary: Chemical synaptic transmission is modulated to accommodate different activity levels, thus enabling homeostatic scaling in pre- and postsynaptic compartments. In nematodes, cholinergic neurons use neuropeptide signaling to modulate synaptic
Externí odkaz:
https://doaj.org/article/8a9822cab6a544b396e05fc3fadc6fc8
Autor:
Amelie C. F. Bergs, Jana F. Liewald, Silvia Rodriguez-Rozada, Qiang Liu, Christin Wirt, Artur Bessel, Nadja Zeitzschel, Hilal Durmaz, Adrianna Nozownik, Holger Dill, Maëlle Jospin, Johannes Vierock, Cornelia I. Bargmann, Peter Hegemann, J. Simon Wiegert, Alexander Gottschalk
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Optogenetic actuation regimes are often static, which allows perturbation, but not true control of neuronal activity. Here, the authors describe an all-optical method for bidirectional steering of membrane potential, in closed loop, in C. elegans mus
Externí odkaz:
https://doaj.org/article/4373263f0a2a4c2cbd268fdc4a4ba5a6
Autor:
Wagner Steuer Costa, Petrus Van der Auwera, Caspar Glock, Jana F. Liewald, Maximilian Bach, Christina Schüler, Sebastian Wabnig, Alexandra Oranth, Florentin Masurat, Henrik Bringmann, Liliane Schoofs, Ernst H. K. Stelzer, Sabine C. Fischer, Alexander Gottschalk
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The GABAergic and peptidergic neuron RIS mediates sleep in Caenorhabditis elegans. The authors demonstrated here that RIS also functions as a locomotion stop neuron. Its optogenetic stimulation caused acute and persistent inhibition of locomotion, an
Externí odkaz:
https://doaj.org/article/dadadbc0392146fd8d67f3ec1c6b32b4
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Synaptic vesicle (SV) recycling enables ongoing transmitter release, even during prolonged activity. SV membrane and proteins are retrieved by ultrafast endocytosis and new SVs are formed from synaptic endosomes (large vesicles—LVs). Many proteins
Externí odkaz:
https://doaj.org/article/6053da095cd94e8f8085b41bee4727d1
Autor:
Amelie Bergs, Christian Schultheis, Elisabeth Fischer, Satoshi P Tsunoda, Karen Erbguth, Steven J Husson, Elena Govorunova, John L Spudich, Georg Nagel, Alexander Gottschalk, Jana F Liewald
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191802 (2018)
In optogenetics, rhodopsins were established as light-driven tools to manipulate neuronal activity. However, during long-term photostimulation using channelrhodopsin (ChR), desensitization can reduce effects. Furthermore, requirement for continuous p
Externí odkaz:
https://doaj.org/article/8ba053d63cc847a48c2fe36a55bc581c
Autor:
Amelie C.F. Bergs, Jana F. Liewald, Silvia Rodriguez-Rozada, Qiang Liu, Christin Wirt, Artur Bessel, Nadja Zeitzschel, Hilal Durmaz, Adrianna Nozownik, Maëlle Jospin, Johannes Vierock, Cornelia I. Bargmann, Peter Hegemann, J. Simon Wiegert, Alexander Gottschalk
Excitable cells can be stimulated or inhibited by optogenetics. Since optogenetic actuation regimes are often static, neurons and circuits can quickly adapt, allowing perturbation, but not true control. Hence, we established an optogenetic voltage-cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff6262b53a80cb3c8943ba8a7f1c3e0
https://doi.org/10.1101/2022.06.03.494532
https://doi.org/10.1101/2022.06.03.494532
Autor:
Thilo Henss, Martin Schneider, Dennis Vettkötter, Wagner Steuer Costa, Jana F. Liewald, Alexander Gottschalk
Publikováno v:
cAMP Signaling ISBN: 9781071622445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d92ec08ff9ff9d360f91264e09e2a29
https://doi.org/10.1007/978-1-0716-2245-2_4
https://doi.org/10.1007/978-1-0716-2245-2_4
Autor:
Bergs Acf, Wagner Steuer Costa, Jana F. Liewald, Alexander Gottschalk, Azimi Hashemi N, Christina Schüler, Bach M, Scheiwe Ar
Publikováno v:
Proceedings of the National Academy of Sciences. 116:17051-17060
Genetically encoded voltage indicators (GEVIs) based on microbial rhodopsins utilize the voltage-sensitive fluorescence of all- trans retinal (ATR), while in electrochromic FRET (eFRET) sensors, donor fluorescence drops when the rhodopsin acts as dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::275105c4d320a4ae1ed0ce58777d69b1
https://doi.org/10.1073/pnas.1902443116
https://doi.org/10.1073/pnas.1902443116
Publikováno v:
BIOspektrum. 25:398-401
In rhodopsin-based optogenetics the light-activatable cation channel ChR2 is employed to selectively gain control over single neurons. As arising experimental questions become more and more challenging, there is a strong need to further expand the op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82abd635bef0502cb49cd0858ac4d6b8
https://doi.org/10.1007/s12268-019-1069-z
https://doi.org/10.1007/s12268-019-1069-z
Autor:
Jánosi B, Szi-chieh Yu, Jana F. Liewald, Alexander Gottschalk, Amelie C. F. Bergs, Jiajie Shao, Umbach S, Martin W. Schneider, Alcantara Ic
Synapses are intricately organized subcellular compartments in which molecular machines cooperate to ensure spatiotemporally precise transmission of chemical signals. Key components of this machinery are voltage-gated Ca2+-channels (VGCCs), that tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f85cc6cc08d2b4cd8cc271f0e46f599
https://doi.org/10.1101/2021.02.01.429206
https://doi.org/10.1101/2021.02.01.429206