Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Janaína K. Barbiero"'
Autor:
Janaína K. Barbiero, Daniele C. Ramos, Suelen Boschen, Taysa Bassani, Cláudio Da Cunha, Maria A. B. F. Vital
Publikováno v:
Behavioural pharmacology. 33(8)
Parkinson's disease is a neurodegenerative disease, the etiology of which remains unknown, but some likely causes include oxidative stress, mitochondrial dysfunction and neuroinflammation. Peroxisome-proliferator-activated receptor (PPAR) agonists ha
Autor:
Ronise M. Santiago, Maria Fernanda de Paula Werner, Maria A.B.F. Vital, Claudio Da Cunha, Marcelo M.S. Lima, Fernanda S. Tonin, Janaína K. Barbiero, Suelen Lucio Boschen, Luisa Mota da Silva
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 53:35-44
Parkinson's disease (PD) is a chronic neurodegenerative disorder characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The etiology and pathogenesis of PD are still unknown, however, many evidences su
Autor:
Raisa W. Gradowski, Ronise M. Santiago, Tiago Zaminelli, Maria A.B.F. Vital, Daniele Maria-Ferreira, Cristiane Hatsuko Baggio, Taysa Bervian Bassani, Janaína K. Barbiero
Publikováno v:
Neurotoxicity Research. 26:351-362
Idiopathic Parkinson's disease is a neurodegenerative disorder that affects approximately 1 % of the population over 55 years of age. The disease manifests itself through motor and nonmotor symptoms induced mainly by the neurodegeneration of dopamine
Autor:
Caroline Santos Capitelli, Maria A.B.F. Vital, Angélica Cristina Alves, Lucas Felipe de Oliveira, Carolina Salomão Lopes, Janaína K. Barbiero, Valdo José Dias da Silva
Publikováno v:
International Journal of Medical Sciences
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) animal model is a useful tool to study Parkinson's disease (PD) and was used in the present study to investigate the potential beneficial as well as deleterious effects of systemic bone-marrow m
Autor:
Claudio Da Cunha, Donita L. Robinson, Peter Redgrave, Janaína K. Barbiero, Daniele C. Ramos, Laura N. Pulido, Bernardo F.C. Lima, Alexander Gómez-A
Publikováno v:
Neuroscience. 349
Midbrain dopamine neurons play critical roles in reward- and aversion-driven associative learning. However, it is not clear whether they do this by a common mechanism or by separate mechanisms that can be dissociated. In the present study we addresse
Autor:
Camila Guimarães Moreira, Patrícia A. Dombrowski, Pamela Sabioni, Mariza Bortolanza, Marcelo M.S. Lima, Claudio Da Cunha, Maria A.B.F. Vital, Janaína K. Barbiero, Deborah Ariza
Publikováno v:
Neurotoxicity Research. 21:291-301
Rotenone exposure in rodents provides an interesting model for studying mechanisms of toxin-induced dopaminergic neuronal injury. However, several aspects remain unclear regarding the effects and the accuracy of rotenone as an animal model of Parkins
Autor:
Maria A.B.F. Vital, Deborah Ariza, Janaína K. Barbiero, Marcelo M.S. Lima, Roberto Andreatini, Ronise M. Santiago, Lívia H. Morais
Publikováno v:
Behavioural Brain Research. 216:186-192
The present study investigated the neurochemical, motor and cognitive effects of pioglitazone in a rat model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). In the first experiment, we administered MPTP, and 1 h
Autor:
Suelen Lucio Boschen, Maria A.B.F. Vital, Ronise M. Santiago, M.M.S. Lima, Tiago Zaminelli, Roberto Andreatini, Janaína K. Barbiero, C. Da Cunha, Fernanda S. Tonin
Publikováno v:
Neuroscience. 300
Depression is one of the most common psychiatric symptoms in patients with Parkinson’s disease (PD). Some authors have reported that depression is characterized by activation of the inflammatory response. Animal models of PD also present with depre
Autor:
Maria A.B.F. Vital, Raisa W. Gradowski, Suelen Lucio Boschen, Claudio Da Cunha, Roberto Andreatini, Marcelo M.S. Lima, Janaína K. Barbiero, Tiago Zaminelli, Taysa Bervian Bassani, Ronise M. Santiago
Publikováno v:
Brain research. 1593
Parkinson׳s disease (PD) is a neurodegenerative disorder characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Systemic and intranigral exposure to rotenone in rodents reproduces many of the pathol
Autor:
Claudio Da Cunha, Maria A.B.F. Vital, Daniele Suzete Persike, Marcelo M.S. Lima, Maria José da Silva Fernandes, Fernanda S. Tonin, Ronise M. Santiago, Suelen Lucio Boschen, Janaína K. Barbiero
Publikováno v:
Behavioural brain research. 274
A large body of evidence suggests that peroxisome proliferator-activated receptor (PPAR) agonists may improve some of the pathological features of Parkinson's disease (PD). In the present study, we evaluated the effects of the PPAR-α agonist fenofib