Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jana, Reinemund"'
Autor:
Thomas Unger, Frank S. Zollmann, Christa Thöne-Reineke, Jennifer Schmitz, Heiko Funke-Kaiser, Sebastian Kirsch, Daniela Zaade, Kristin Lucht, Jan H. Schefe, Petra Goldin-Lang, Yaosi Li, Kerstin Seidel, Kristin Schmerbach, Jana Reinemund, Sabrina Klare
Publikováno v:
Brain Pathology. 21:31-43
Stroke is one of the major medical burdens in industrialized countries. Animal experiments indicate that blockade of the angiotensin AT1 receptor (AT1R) improves neurological outcome after cerebral ischemia. These protective effects are partially med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37c37ef5b6e1bd9eda09fce94285ae86
https://doi.org/10.1111/j.1750-3639.2010.00427.x
https://doi.org/10.1111/j.1750-3639.2010.00427.x
Autor:
Sebastian Kirsch, Kerstin Seidel, Ulrike Muscha Steckelings, Thomas Unger, Marco Sifringer, Claudia Spies, Jan H. Schefe, Clarissa von Haefen, Jana Reinemund, Heiko Funke-Kaiser, Mario Menk
Publikováno v:
Alcohol. 44:495-506
Molecular mechanisms accompanying ethanol-induced cytotoxicity remain to be defined. The renin–angiotensin system with its respective receptors, the angiotensin AT1 and AT2 receptor (AT1R and AT2R), has been implicated in these processes. The AT2R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b9b10deb266a3d8b54de892945c5a8
https://doi.org/10.1016/j.alcohol.2010.05.005
https://doi.org/10.1016/j.alcohol.2010.05.005
Autor:
Gabor Olah, Yaosi Li, Jan H. Schefe, Jens Schacherl, Petra Goldin-Lang, Kerstin Seidel, Ulrike Muscha Steckelings, Daniela Zaade, Thomas Unger, Marlen Katerbaum, Mario Menk, Csaba Szabó, Heiko Funke-Kaiser, Franziska Rompe, Sabrina Klare, Jana Reinemund
Publikováno v:
Biochemical Pharmacology. 77:1795-1805
The renin-angiotensin system (RAS) plays a crucial role in cardiovascular and neuronal (patho-)physiology. The angiotensin AT2 receptor (AT2R) seems to counteract the proinflammatory, prohypertrophic and profibrotic actions of the AT1 receptor. Recen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e86bca059a7566626ed852e88df6aa
https://doi.org/10.1016/j.bcp.2009.02.025
https://doi.org/10.1016/j.bcp.2009.02.025
Publikováno v:
Experimental Dermatology. 15:643-648
Recently, we demonstrated the presence of a complete rennin–angiotensin system in human skin and the up-regulation of angiotensin AT1- and AT2-receptors in cutaneous wounds. However, the characterisation of cutaneous actions of angiotensin II (Ang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401d38d35705e073bd13d09260dc9d2d
https://doi.org/10.1111/j.1600-0625.2006.00439j.x
https://doi.org/10.1111/j.1600-0625.2006.00439j.x
Autor:
Ulrich Kintscher, Rebecca Hugel, Jana Reinemund, Peter Walden, Ulrike Grittner, Rudolf Volkmer, Frank S. Zollmann, Jan H. Schefe, Antonia Hope, Yaosi Li, Sebastian Kirsch, Wolfgang Maier, Thomas Unger, Andreas Schlosser, Johannes Kornhuber, Heiko Funke-Kaiser, Kristin Schmerbach, Sylvia Scheele, Jennifer Schmitz, Heike Kölsch, Lutz Frölich, Peter Marschall, Sabrina Klare, Jens Schacherl, Petra Goldin-Lang, Kerstin Seidel, Julia Schimkus, Michael G. Klein, Oliver Peters, Mario Menk
Publikováno v:
Journal of Neuroscience, 32(47), 16807-16820. Society for Neuroscience
Genetic factors strongly contribute to the pathogenesis of sporadic Alzheimer's disease (AD). Nevertheless, genome-wide association studies only yielded single nucleotide polymorphism loci of moderate importance. In contrast, microsatellite repeats a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587bff6d5ea1e0391e4bd0b1b2fb8e59
https://pubmed.ncbi.nlm.nih.gov/23175834
https://pubmed.ncbi.nlm.nih.gov/23175834
Autor:
Elena, Bochukova, Nadia, Schoenmakers, Maura, Agostini, Erik, Schoenmakers, Odelia, Rajanayagam, Julia M, Keogh, Elana, Henning, Jana, Reinemund, Evelien, Gevers, Margarita, Sarri, Kate, Downes, Amaka, Offiah, Assunta, Albanese, David, Halsall, John W R, Schwabe, Murray, Bain, Keith, Lindley, Francesco, Muntoni, Faraneh, Vargha-Khadem, Faraneh Vargha, Khadem, Mehul, Dattani, I Sadaf, Farooqi, Mark, Gurnell, Krishna, Chatterjee
Publikováno v:
The New England journal of medicine. 366(3)
Thyroid hormones exert their effects through alpha (TRα1) and beta (TRβ1 and TRβ2) receptors. Here we describe a child with classic features of hypothyroidism (growth retardation, developmental retardation, skeletal dysplasia, and severe constipat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8420b63ddec48cfe12a383053d18e2e7
https://pubmed.ncbi.nlm.nih.gov/22816109
https://pubmed.ncbi.nlm.nih.gov/22816109
Autor:
Kerstin, Seidel, Sebastian, Kirsch, Kristin, Lucht, Daniela, Zaade, Jana, Reinemund, Jennifer, Schmitz, Sabrina, Klare, Yaosi, Li, Jan H, Schefe, Kristin, Schmerbach, Petra, Goldin-Lang, Frank S, Zollmann, Christa, Thöne-Reineke, Thomas, Unger, Heiko, Funke-Kaiser
Publikováno v:
Brain Pathol
Stroke is one of the major medical burdens in industrialized countries. Animal experiments indicate that blockade of the angiotensin AT1 receptor (AT1R) improves neurological outcome after cerebral ischemia. These protective effects are partially med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1a9a25768c79fa1dd385ae3e9ee868e
https://pubmed.ncbi.nlm.nih.gov/20731660
https://pubmed.ncbi.nlm.nih.gov/20731660
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 11 (2010)
The angiotensin AT 2 receptor (AT2R) represents an important component of the renin-angiotensin system since it is involved in the (patho) physiology of different cardiovascular and neuronal diseases. Furthermore, AT2 receptors can partly mediate ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07032c0286a89ab2772f14d42f0bee39
https://doaj.org/article/58e617752ee34c148251837729688ba3
https://doaj.org/article/58e617752ee34c148251837729688ba3
Autor:
Mario Menk, Jan H. Schefe, Karin Effertz, Patricia Ruiz, Pier Paolo Pandolfi, Jana Reinemund, Heiko Funke-Kaiser, Robin M. Hobbs, Thomas Unger
Publikováno v:
Circulation research. 99(12)
A human renin/prorenin receptor (RER) has recently been cloned. To gain insight into the molecular function of the RER, we studied its signal transduction mechanisms. Initially, we found a ubiquitous and intracellular expression pattern of the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431e4366d25812b27ff5fbfe97cead7b
https://pubmed.ncbi.nlm.nih.gov/17158342
https://pubmed.ncbi.nlm.nih.gov/17158342
Autor:
Jana Reinemund, Shane McCarthy, Salim Mottagui-Tabar, Björn Andersson, Claes Wahlestedt, Markus Heilig
Publikováno v:
Alcohol and alcoholism (Oxford, Oxfordshire). 39(5)
Aims: To examine whether polymorphic variants of the HTR2C gene are associated with diagnosis of alcohol dependence. Methods: We compared allele frequencies of five HTR2C promoter polymorphisms in a Nordic population of alcohol dependent individuals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164cee06d188dd983504513a3f188f74
https://pubmed.ncbi.nlm.nih.gov/15304380
https://pubmed.ncbi.nlm.nih.gov/15304380