Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jana, Burkhardt"'
Autor:
Niklas Deventer, Tymoteusz Budny, Georg Gosheger, Marieke de Vaal, Jana Burkhardt, Nils Deventer
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background The aneurysmal bone cyst (ABC) is a benign, but locally aggressive cystic lesion of the bone. It usually occurs in the metaphysis of long bones of adolescents and young adults but can also affect the pelvis. Methods This single-ce
Externí odkaz:
https://doaj.org/article/487f8cbb4c2c490a9f114719e8b70f05
Autor:
Jens Lipka, Manuela Semmler-Behnke, Alexander Wenk, Jana Burkhardt, Achim Aigner, Wolfgang Kreyling
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 1175-1178 (2016)
Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the 32P-radioactivity in the whole
Externí odkaz:
https://doaj.org/article/b9eca9bf1ed344759ce3278a70432837
Autor:
Susanne Przybylski, Michaela Gasch, Anne Marschner, Marcus Ebert, Alexander Ewe, Gisa Helmig, Nadja Hilger, Stephan Fricke, Susanne Rudzok, Achim Aigner, Jana Burkhardt
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176517 (2017)
INTRODUCTION:One of the main obstacles in the widespread application of gene therapeutic approaches is the necessity for efficient and safe transfection methods. For the introduction of small oligonucleotide gene therapeutics into a target cell, nano
Externí odkaz:
https://doaj.org/article/b941bdf6cdf24198a3b2aea67c33ba79
Autor:
Niklas Deventer, Tymoteusz Budny, Georg Gosheger, Marieke Vaal, Jana Burkhardt, Nils Deventer
BACKGROUND: The aneurysmal bone cyst (ABC) is a benign, but locally aggressive cystic lesion of the bone. It usually occurs in the metaphysis of long bones of adolescents and young adults but can also affect the pelvis.METHODS: This single-center stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be8cfddc3e988cf23e541f76a1dc66c9
https://doi.org/10.21203/rs.3.rs-1401862/v1
https://doi.org/10.21203/rs.3.rs-1401862/v1
Publikováno v:
Genetics and Molecular Biology, Vol 35, Iss 3, Pp 567-574 (2012)
An important area of genetic research is the identification of functional mechanisms in polymorphisms associated with diseases. A highly relevant functional mechanism is the influence of polymorphisms on gene expression levels (differential allelic e
Externí odkaz:
https://doaj.org/article/9641204a94b74493a3626109b888a531
Autor:
Jana Burkhardt, Mechthild Blume, Elisabeth Petit-Teixeira, Vitor Hugo Teixeira, Anke Steiner, Elfi Quente, Grit Wolfram, Markus Scholz, Céline Pierlot, Paola Migliorini, Stefano Bombardieri, Alejandro Balsa, René Westhovens, Pilar Barrera, Timothy R D J Radstake, Helena Alves, Thomas Bardin, Bernard Prum, Frank Emmrich, François Cornelis, Peter Ahnert, Holger Kirsten
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103872 (2014)
In rheumatoid arthritis (RA), a key event is infiltration of inflammatory immune cells into the synovial lining, possibly aggravated by dysregulation of cellular adhesion molecules. Therefore, single nucleotide polymorphisms of 14 genes involved in c
Externí odkaz:
https://doaj.org/article/bdc89cf155be4f199c0a904ba3741878
Autor:
Alexander Wenk, Wolfgang G. Kreyling, Manuela Semmler-Behnke, Jana Burkhardt, Jens Lipka, Achim Aigner
Publikováno v:
Data in Brief, Vol 7, Iss, Pp 1175-1178 (2016)
Data Brief 7, 1175-1178 (2016)
Data in Brief
Data Brief 7, 1175-1178 (2016)
Data in Brief
Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the 32P-radioactivity in the whole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3e45789c0548fc166c1ea487f7500f
http://www.sciencedirect.com/science/article/pii/S2352340916302001
http://www.sciencedirect.com/science/article/pii/S2352340916302001
Autor:
Alexander Wenk, Jana Burkhardt, Jens Lipka, Manuela Semmler-Behnke, Achim Aigner, Wolfgang G. Kreyling
Publikováno v:
International Journal of Pharmaceutics. 500:227-235
Successful gene therapy requires stability and sufficient bioavailability of the applied drug at the site of action. In the case of RNA interference (RNAi), non-viral vectors play a promising role for delivering intact siRNA molecules. We selected a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394e05a226ac96834aea64ade21f93c0
https://doi.org/10.1016/j.ijpharm.2016.01.038
https://doi.org/10.1016/j.ijpharm.2016.01.038
Autor:
Jana Burkhardt, Ivonne Czepezauer, Jens Brauer, Holger Kirsten, B. Mueller, Elfi Quente, Johannes Boltze, Peter Ahnert, Arndt Wilcke
Publikováno v:
Genes, Brain and Behavior. 13:350-356
Dyslexia is characterized by impaired reading and spelling. The disorder has a prevalence of about 5% in Germany, and a strong hereditary component. Several loci are thought to be involved in the development of dyslexia. Scerri et al. identified eigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e45be885f37d82874c9e34c67e15b7
https://doi.org/10.1111/gbb.12118
https://doi.org/10.1111/gbb.12118
Autor:
Susanne Przybylski, Achim Aigner, Alexander Ewe, Dietmar Appelhans, Jana Burkhardt, Andreas Janke
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 230
The delivery of nucleic acids, particularly of small RNA molecules like siRNAs for the induction of RNA interference (RNAi), still represents a major hurdle with regard to their application in vivo. Possible therapeutic applications thus rely on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e17fb29fdf49ae8aafac85f69af4c75
https://pubmed.ncbi.nlm.nih.gov/27061141
https://pubmed.ncbi.nlm.nih.gov/27061141