Zobrazeno 1 - 10 of 122 pro vyhledávání: '"Jan-Willem Arends"'
1
HER2 gene amplification in patients with breast cancer with equivocal IHC results
Autor: Lotus Sterk, Gerrit K. J. Hooijer, Jan Willem Arends, Marc J. van de Vijver, Mike Kliffen, Joost M van Gorp, Henrique J. Ruijter, Sybren L. Meijer, Petra M. Nederlof, Jelle Wesseling, Vincent T.H.B.M. Smit
Publikováno v: Journal of Clinical Pathology, 64(12), 1069-1072
Journal of clinical pathology, 64(12), 1069-1072. BMJ Publishing Group
Journal of Clinical Pathology, 64(12), 1069-1072. BMJ PUBLISHING GROUP
AimsEquivocal human epidermal growth factor receptor 2 protein (HER2) (2+) immunohistochemistry (IHC) is subject to significant interobserver variation and poses a challenge in obtaining a definitive positive or negative test result. This equivocal t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bde501ba93bab9f062ba82a38627d77
https://doi.org/10.1136/jclinpath-2011-200019
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3
Is the Distinction Between Superficial Pressure Ulcers and Moisture Lesions Justifiable? A Clinical-Pathologic Study
Autor: Jan Willem Arends, Ronald H Houwing, Eddy S M Koopman, Jeen R E Haalboom, Marijke R. Canninga-van Dijk
Publikováno v: SKINmed. 6:113-117
Objective. Pressure ulcers are classified into 4 distinct stages, which allows comparisons between institutions and even countries. Recently, attempts have been made to single out so-called moisture lesions from the early stages of pressure ulcer les
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29182a668d4bab17e02802f821b6fc16
https://doi.org/10.1111/j.1540-9740.2007.06357.x
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4
An Unexpected Detrimental Effect on the Incidence of Heel Pressure Ulcers After Local 5% DMSO Cream Application: A Randomized, Double-blind Study in Patients at Risk for Pressure Ulcers
Autor: Ronald, Houwing, Wil, van der Zwet, Sweder, van Asbeck, Ruud, Halfens, Jan, Willem Arends
Publikováno v: Wounds : a compendium of clinical research and practice. 20(4)
Background. Ischemia-reperfusion injury and reactive oxygen species (ROS) are considered to play an important role in the pathogenesis of pressure ulcers (PU). Antioxidants may diminish the inflammation and damage of these ROS in pressure ulcer forma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6dcf06136a5aeaabcf5522cf31b685b0
https://pubmed.ncbi.nlm.nih.gov/25942326
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5
Rectal Carcinoma Treated with Short-Term Preoperative Radiotherapy followed by Abdominoperineal Resection
Autor: M. Eeftinck Schattenkerk, M.G. van der Vaart, W.C. van der Zwet, E.H. Eddes, Jan Willem Arends
Publikováno v: Digestive Surgery. 23:173-178
Background: Treatment of choice for rectal carcinoma is short-term preoperative radiotherapy (5 × 5 Gy) followed by a total mesorectal excision (TME) of the rectum. This treatment has led to a reduction in local recurrence 2 years after surgery from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0c3354b2dcfd1d88c5bb58eed0c3295
https://doi.org/10.1159/000094552
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6
Isolation of human antibodies to tumor-associated endothelial cell markers by in vitro human endothelial cell selection with phage display libraries
Autor: Edith van der Linden, Sietske Satijn, Hennie R. Hoogenboom, Patrick Chames, H.H.C. Lichtenbeld, Angelique Huijbers, Jan-Willem Arends, Ricardo Mutuberria
Publikováno v: Journal of Immunological Methods. 287:31-47
Human antibodies selectively targeting angiogenic vessels hold great promise for the immunotherapy of human malignancies and can help to elucidate the molecular mechanisms regulating angiogenesis. By selecting a large antibody phage display library o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366f065dc4b6cf220ae1d9b31ca77533
https://doi.org/10.1016/j.jim.2004.01.011
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7
Simultaneous detection of apoptosis and proliferation in colorectal carcinoma by multiparameter flow cytometry allows separation of high and low-turnover tumors with distinct clinical outcome
Autor: Marius Nap, Alfons G. H. Kessels, Jan Willem Arends, Mathie P.G. Leers, J. Dennis Rupa, Andrea J. Gerbers, Adriaan P. de Bruïne, Bert Schutte
Publikováno v: Cancer. 97:2404-2411
BACKGROUND Dukes C colorectal carcinoma is treated with adjuvant chemotherapy. Adjuvant treatment is not standard for patients with Dukes B tumors, even though about 20% of patients within this tumor stage die of recurrent disease. The authors invest
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4cfc656f2ec3a37b67834f1917113d6b
https://doi.org/10.1002/cncr.11366
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8
Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability
Autor: Jan Willem Arends, Walter Giaretti, Anton F.P.M. de Goeij, Gerrit A. Meijer, Richard A. Williams, Jan P. A. Baak, Andrea Sciutto, Mario Hermsen, Marjan M. Weiss, Cindy Postma, Guido M.J.M. Roemen, A. Rapallo
Publikováno v: Gastroenterology. 123:1109-1119
Background & Aims: Current models of colorectal adenoma to carcinoma progression do not fully reflect the genetic heterogeneity and complexity of the disease. The aim of the present study was to identify genetic changes discriminating adenomas that h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bbb4e69d8c7eaf99ebfee6182550c6
https://doi.org/10.1053/gast.2002.36051
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9
Target validation for genomics using peptide-specific phage antibodies: A study of five gene products overexpressed in colorectal cancer
Autor: Simon E. Hufton, Andrea J Gerbers, Judy R. van Beijnum, Adriaan P. de Bruïne, Peter T.M. Moerkerk, Jan-Willem Arends, Hennie R. Hoogenboom
Publikováno v: International Journal of Cancer. 101:118-127
Genomic approaches are providing a wealth of information on differential gene expression in cancer. To identify the most interesting genes amongst the many identified, high-throughput methods for analysis of genes at the translational level are requi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4550ee9fc5fb82b1e2220025034a565c
https://doi.org/10.1002/ijc.10584
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10
K-ras mutations and RASSF1A promoter methylation in colorectal cancer
Autor: James G. Herman, Jan Willem Arends, Manon van Engeland, Mirian Brink, Adriaan P. de Bruïne, Anton F.P.M. de Goeij, Piet A. van den Brandt, Marco M.M. Pachen, Matty P. Weijenberg, Guido M.J.M. Roemen
Publikováno v: Oncogene, 21(23), 3792-3795. Nature Publishing Group
Human cancer is characterized by genetic and epigenetic alterations. In this study we provide evidence for the interruption of Ras signaling in sporadic colorectal cancer (CRC) by either genetic activation of the K-ras oncogene or epigenetic silencin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bee2d9baa1009e732f4ef230e0cd5a
https://doi.org/10.1038/sj.onc.1205466
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