Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Jan-Terje Andersen"'
Autor:
Trung The Tran, Eline Benno Vaage, Adi Mehta, Adity Chopra, Lisa Tietze, Anette Kolderup, Aina Anthi, Marton König, Gro Nygaard, Andreas Lind, Fredrik Müller, Lise Sofie Nissen-Meyer, Per Magnus, Lill Trogstad, Siri Mjaaland, Arne Søraas, Karsten Midtvedt, Anders Åsberg, Andreas Barratt-Due, Asle W. Medhus, Marte Lie Høivk, Knut Lundin, Randi Fuglaas Karlsen, Reidun Dahle, Karin Danielsson, Kristine Stien Thomassen, Grete Birkeland Kro, Rebecca J. Cox, Fan Zhou, Nina Langeland, Pål Aukrust, Espen Melum, Tone Lise Åvitsland, Kristine Wiencke, Jan Cato Holter, Ludvig A. Munthe, Gunnveig Grødeland, Jan-Terje Andersen, John Torgils Vaage, Fridtjof Lund-Johansen
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Diagnostic assays currently used to monitor the efficacy of COVID-19 vaccines measure levels of antibodies to the receptor-binding domain of ancestral SARS-CoV-2 (RBDwt). However, the predictive value for protection against new variants of c
Externí odkaz:
https://doaj.org/article/826e753e9af04c97b4bfcbbc931c5ef1
Autor:
Trung The Tran, Eline Benno Vaage, Adi Mehta, Adity Chopra, Lisa Tietze, Anette Kolderup, Aina Anthi, Marton König, Gro Nygaard, Andreas Lind, Fredrik Müller, Lise Sofie Nissen-Meyer, Per Magnus, Lill Trogstad, Siri Mjaaland, Arne Søraas, Karsten Midtvedt, Anders Åsberg, Andreas Barratt-Due, Asle W. Medhus, Marte Lie Høivik, Knut Lundin, Randi Fuglaas Karlsen, Reidun Dahle, Karin Danielsson, Kristine Stien Thomassen, Grete Birkeland Kro, Rebecca J. Cox, Fan Zhou, Nina Langeland, Pål Aukrust, Espen Melum, Tone Lise Åvitsland, Kristine Wiencke, Jan Cato Holter, Ludvig A. Munthe, Gunnveig Grødeland, Jan-Terje Andersen, John Torgils Vaage, Fridtjof Lund-Johansen
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/8b6c83d5e6d54724bfe01aa963156ef8
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended serum half-life, achieved through pH-dependent binding to the neonatal Fc receptor (FcRn). While prior research has mainly investigated
Externí odkaz:
https://doaj.org/article/8e21d7845285420f8c4d1cd91773b5b4
Autor:
Marta Lustig, Christoph Hahn, Marie Leangen Herigstad, Jan Terje Andersen, Jeanette H. W. Leusen, Renate Burger, Thomas Valerius
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Tumor cell phagocytosis by macrophages is considered a relevant mechanism of action for many therapeutic IgG antibodies. However, tumor cells employ several mechanisms to evade immune recognition, including hypersialylation. Here, we describe how red
Externí odkaz:
https://doaj.org/article/da76518ed3c34d60bab02c646afed694
Autor:
Rahmad Akbar, Habib Bashour, Puneet Rawat, Philippe A. Robert, Eva Smorodina, Tudor-Stefan Cotet, Karine Flem-Karlsen, Robert Frank, Brij Bhushan Mehta, Mai Ha Vu, Talip Zengin, Jose Gutierrez-Marcos, Fridtjof Lund-Johansen, Jan Terje Andersen, Victor Greiff
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Although the therapeutic efficacy and commercial success of monoclonal antibodies (mAbs) are tremendous, the design and discovery of new candidates remain a time and cost-intensive endeavor. In this regard, progress in the generation of data describi
Externí odkaz:
https://doaj.org/article/aa3c08b3fb154e0dafa6136e2d38c0d4
Autor:
Rahmad Akbar, Philippe A. Robert, Cédric R. Weber, Michael Widrich, Robert Frank, Milena Pavlović, Lonneke Scheffer, Maria Chernigovskaya, Igor Snapkov, Andrei Slabodkin, Brij Bhushan Mehta, Enkelejda Miho, Fridtjof Lund-Johansen, Jan Terje Andersen, Sepp Hochreiter, Ingrid Hobæk Haff, Günter Klambauer, Geir Kjetil Sandve, Victor Greiff
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Generative machine learning (ML) has been postulated to become a major driver in the computational design of antigen-specific monoclonal antibodies (mAb). However, efforts to confirm this hypothesis have been hindered by the infeasibility of testing
Externí odkaz:
https://doaj.org/article/dcc3e950ba4a40b789231de4ffed3cb1
Autor:
Arne Søraas, Gunnveig Grødeland, Beathe Kiland Granerud, Thor Ueland, Andreas Lind, Børre Fevang, Sarah L. Murphy, Camilla Huse, Anders Benteson Nygaard, Anne Katrine Steffensen, Huda al-Baldawi, Mona Holberg-Petersen, Lise Lima Andresen, Camilla Ågnes, Trine Ranheim, Ylva Schanke, Mette Istre, John Arne Dahl, Adity Chopra, Susanne Dudman, Mari Kaarbø, Jan Terje Andersen, Eline Benno Vaage, Trung The Tran, John Torgils Vaage, Annika E. Michelsen, Fredrik Müller, Pål Aukrust, Bente Halvorsen, Tuva B. Dahl, Jan Cato Holter, Fridtjof Lund-Johansen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundResults showing that sera from double vaccinated individuals have minimal neutralizing activity against Omicron have been interpreted as indicating the need for a third vaccine dose for protection. However, there is little information about
Externí odkaz:
https://doaj.org/article/b48aae54e3e14b67ad888efba97122e0
Autor:
E. Sally Ward, Deborah Gelinas, Erwin Dreesen, Jolien Van Santbergen, Jan Terje Andersen, Nicholas J. Silvestri, Joseph E. Kiss, Darrell Sleep, Daniel J. Rader, John J. P. Kastelein, Els Louagie, Gestur Vidarsson, Isabel Spriet
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Serum albumin (SA), the most abundant soluble protein in the body, maintains plasma oncotic pressure and regulates the distribution of vascular fluid and has a range of other important functions. The goals of this review are to expand clinical knowle
Externí odkaz:
https://doaj.org/article/184d31362c494626a9242fddebe1de64
Autor:
Simone Mester, Mitchell Evers, Saskia Meyer, Jeannette Nilsen, Victor Greiff, Inger Sandlie, Jeanette Leusen, Jan Terje Andersen
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Albumin has a serum half-life of 3 weeks in humans. This feature can be used to improve the pharmacokinetics of shorter-lived biologics. For instance, an albumin-binding domain (ABD) can be used to recruit albumin. A prerequisite for such design is t
Externí odkaz:
https://doaj.org/article/d68dea8700bb4629943b62d258a17e3a
Autor:
Anna Zakrzewicz, Celina Würth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen, Vladimir Bobkov, Ritva Tikkanen
Publikováno v:
Cells, Vol 11, Iss 6, p 942 (2022)
Pemphigus vulgaris is an autoimmune blistering disease of the epidermis, caused by autoantibodies against desmosomal proteins, mainly desmogleins 1 and 3, which induce an impairment of desmosomal adhesion and blister formation. Recent findings have s
Externí odkaz:
https://doaj.org/article/94bff078217b4747b791e79e694256c3