Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Jan-Pieter Konsman"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44275 (2012)
CONTEXT: Because positive biomedical observations are more often published than those reporting no effect, initial observations are often refuted or attenuated by subsequent studies. OBJECTIVE: To determine whether newspapers preferentially report on
Externí odkaz:
https://doaj.org/article/c7d26431f7fa4a2ea7d2ad27482f01eb
Blood–brain borders: a proposal to address limitations of historical blood–brain barrier terminology
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Many neuroscientists use the term Blood–Brain Barrier (BBB) to emphasize restrictiveness, often equating or reducing the notion of BBB properties to tight junction molecules physically sealing cerebral endothelial cells, rather than pointi
Externí odkaz:
https://doaj.org/article/7fba3f35a2594aaeadd273c81175ae8d
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
Scientific and philosophical accounts of cognition and perception have traditionally focused on the brain and external sense organs. The extended view of embodied cognition suggests including other parts of the body in these processes. However, one o
Externí odkaz:
https://doaj.org/article/2ea3450efc47400b881f7a0709acd780
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106231- (2023)
Astrocytes are in contact with the vasculature, neurons, oligodendrocytes and microglia, forming a local network with various functions critical for brain homeostasis. One of the primary responders to brain injury are astrocytes as they detect neuron
Externí odkaz:
https://doaj.org/article/e9cb6000b89947c286c8d1640246d6b6
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 3, Pp 249-260 (2021)
Abstract Background Magnetic resonance imaging (MRI) of rodents combined with histology allows to determine what mechanisms underlie functional and structural brain changes during sepsis‐associated encephalopathy. However, the effects of MRI perfor
Externí odkaz:
https://doaj.org/article/9748ae48a0bf46b9a26313c6ba790af7
Autor:
Jan Pieter Konsman
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Animals, including human beings, modify their behavior when they fall sick. Interestingly, sociology, biology, and psychology have at different times in their history developed constructs of illness or sickness behavior. The aims of the present paper
Externí odkaz:
https://doaj.org/article/8ddd1e6ff13844dab58bac4c420e50c0
Autor:
Jan Pieter Konsman
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 140 (2022)
In spite of the brain-protecting tissues of the skull, meninges, and blood-brain barrier, some forms of injury to or infection of the CNS can give rise to cerebral cytokine production and action and result in drastic changes in brain function and beh
Externí odkaz:
https://doaj.org/article/3194b1b3f5df4763aaf0d5dd461373d5
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1030 (2021)
Sickness behavior, characterized by on overall reduction in behavioral activity, is commonly observed after bacterial infection. Sickness behavior can also be induced by the peripheral administration of Gram-negative bacterial lipopolysaccharide (LPS
Externí odkaz:
https://doaj.org/article/999880b350d34d97b6e331d8cd246638
Autor:
Jan Pieter Konsman, Teresa M. Reyes, Adam Hiltz, Kelsey R. Lloyd, Marissa A. Smail, Brittany L. Smith, Collin J. Laaker
Publikováno v:
Brain Behav Immun
Survivors of acute lymphoblastic leukemia (ALL), the most common childhood cancer, are at increased risk for long-term cognitive problems, including executive function deficits. The chemotherapeutic agent methotrexate (MTX) is used to treat most ALL