Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jan-Philip Meyer"'
Autor:
José Carlos dos Santos, Martin Schäfer, Ulrike Bauder-Wüst, Barbro Beijer, Matthias Eder, Karin Leotta, Christian Kleist, Jan-Philip Meyer, Thomas R. Dilling, Jason S. Lewis, Clemens Kratochwil, Klaus Kopka, Uwe Haberkorn, Walter Mier
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Prostate-specific membrane antigen (PSMA) binding tracers are promising agents for the targeting of prostate tumors. To further optimize the clinically established radiopharmaceutical PSMA-617, novel PSMA ligands for prostate cancer endoradiotherapy
Externí odkaz:
https://doaj.org/article/b5ea39f8dbeb4d3fab741b428d46c1bc
Autor:
Paula Demétrio De Souza França, Jan-Philip Meyer, Tanjeena Mamun, Lukas M. Carter, Marina V. Backer, Christian Mason, Komal Mandleywala, Thomas Reiner, Jason S. Lewis, Joseph M. Backer
Publikováno v:
Molecular Imaging and Biology. 23:340-349
Metastatic breast cancer is the second leading cause of cancer-related death in women. The 5-year survival rate for metastatic breast cancer has remained near 26.9 % for over a decade. The recruitment of hematopoietic stem cells with high expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95cf4f122643169cf272d1d708597d91
https://doi.org/10.1007/s11307-020-01555-z
https://doi.org/10.1007/s11307-020-01555-z
Autor:
Christian A, Mason, Lukas M, Carter, Komal, Mandleywala, Paula Demetrio, de Souza Franca, Jan-Philip, Meyer, Tanjeena, Mamun, Joseph M, Backer, Marina V, Backer, Thomas, Reiner, Jason S, Lewis
Publikováno v:
Mol Imaging Biol
PURPOSE: Metastatic breast cancer is the second leading cause of cancer-related death in women. The 5-year survival rate for metastatic breast cancer has remained near 26.9% for over a decade. The recruitment of hematopoietic stem cells with high exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b427f01adb0cfe01686357d18a849e10
https://pubmed.ncbi.nlm.nih.gov/33156495
https://pubmed.ncbi.nlm.nih.gov/33156495
Publikováno v:
Bioconjugate Chemistry. 27:2791-2807
The advent of click chemistry has had a profound influence on almost all branches of chemical science. This is particularly true of radiochemistry and the synthesis of agents for positron emission tomography (PET), single photon emission computed tom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908b780cbb814d77474492ee53a5ff9a
https://doi.org/10.1021/acs.bioconjchem.6b00561
https://doi.org/10.1021/acs.bioconjchem.6b00561
Autor:
Kimberly J. Edwards, Marina V. Backer, Joseph M. Backer, Jason S. Lewis, Paul Kozlowski, Jan-Philip Meyer
Publikováno v:
Journal of Nuclear Medicine. 57:1811-1816
Vascular endothelial growth factor-A (VEGF-A) acts via 2 vascular endothelial growth factor receptors, VEGFR-1 and VEGFR-2, that play important and distinct roles in tumor biology. We reasoned that selective imaging of these receptors could provide u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e14c3e9916e5ad6fdd185e2b8316a11
https://doi.org/10.2967/jnumed.116.173237
https://doi.org/10.2967/jnumed.116.173237
Autor:
Thomas R. Dilling, Jan-Philip Meyer, Jason S. Lewis, Kathryn M. Tully, Thomas Reiner, James R. Jackson
Pretargeting strategies have gained popularity for the in vivo imaging and therapy of cancer by combining antibodies with small molecule radioligands. In vivo recombination of both moieties can be achieved using the bioorthogonal inverse electron dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb83effefb4c8f97e39ea352066acd6e
https://europepmc.org/articles/PMC6004324/
https://europepmc.org/articles/PMC6004324/
Autor:
Jan-Philip Meyer, Jason S. Lewis, Wolfgang W. Scholz, Paul Kozlowski, Brian M. Zeglis, Dalya Abdel-Atti, Thomas Reiner, Naga Vara Kishore Pillarsetty, Jacob L. Houghton
Publikováno v:
Bioconjugate Chemistry
A first-of-its-kind (18)F pretargeted PET imaging approach based on the bioorthogonal inverse electron demand Diels-Alder (IEDDA) reaction between tetrazine (Tz) and trans-cyclooctene (TCO) is presented. As proof-of-principle, a TCO-bearing immunocon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b29c3d525b75ccbb9589bcedda5dc2e
https://doi.org/10.1021/acs.bioconjchem.5b00504
https://doi.org/10.1021/acs.bioconjchem.5b00504
Autor:
Jan-Philip Meyer, Andrew D. Westwell
Publikováno v:
Fluorinated Pharmaceuticals: Advances in Medicinal Chemistry. :6-17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e63a87f7bd00d692d2d7b83e93935b
https://doi.org/10.4155/fseb2013.14.295
https://doi.org/10.4155/fseb2013.14.295
Autor:
Jason S. Lewis, Kristen M. Cunanan, Paul Kozlowski, Brian M. Zeglis, James R. Jackson, Jan-Philip Meyer, Pierre Adumeau, Thomas R. Dilling
Pretargeting offers a way to enhance target specificity while reducing off-target radiation dose to healthy tissue during payload delivery. We recently reported the development of an (18)F-based pretargeting strategy predicated on the inverse electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8d54f24d2c2c9e580e4284532d464d
https://europepmc.org/articles/PMC6521719/
https://europepmc.org/articles/PMC6521719/
A novel radiochemical approach to 1-(2'-deoxy-2'-[18F]fluoro-β-d -arabinofuranosyl)cytosine (18F-FAC)
Autor:
Christopher McGuigan, Katrin C. Probst, Iuni Margaret Laura Trist, Andrew D. Westwell, Jan-Philip Meyer
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 57:637-644
18F-FAC (1-(2'-deoxy-2'-[18F]fluoro-β-D-arabinofuranosyl)-cytosine) is an important 2'-fluoro-nucleoside-based positron emission tomography (PET) tracer that has been used for in vivo prediction of response to the widely used cancer chemotherapy dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e18b4a020c5092fd8de5bd560cda967
https://doi.org/10.1002/jlcr.3233
https://doi.org/10.1002/jlcr.3233