Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jan-Paul Buschdorf"'
Autor:
Danusa Mar Arcego, Nicholas O’Toole, Zihan Wang, Sachin Patel, Irina Pokhvisneva, Betty Wang, Barbara Barth, Jan-Paul Buschdorf, Patricia Pelufo Silveira, Michael Meaney
Publikováno v:
Biological Psychiatry. 91:S243
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::447ee762a9c131269f54f8391a18a7ef
https://doi.org/10.1016/j.biopsych.2022.02.621
https://doi.org/10.1016/j.biopsych.2022.02.621
Autor:
Zihan Wang, Euclides José de Mendonça Filho, Randriely Merscher Sobreira de Lima, Irina Pokhvisneva, Sachin Patel, Danusa Mar Arcego, Michael J. Meaney, Barbara Barth, Jan-Paul Buschdorf, Nirmala Arul Rayan, Nick O’Toole, Patrícia Pelufo Silveira, Carla Dalmaz
Publikováno v:
Journal of the Endocrine Society
Exposure to stress during the life-course has consistently been associated with neuropsychological disorders, but the precise role of stress released glucocorticoids remains unclear in this context. We aimed at using hippocampal gene expression data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3022c6b6c9f8be5672867b08f364ec
http://europepmc.org/articles/PMC7207636
http://europepmc.org/articles/PMC7207636
Autor:
Fan Zhang, Raghuvaran Shanmugam, Meng How Tan, Cheok Wei Ariel Woo, Kaiwen I Liu, Zi Hao M Chua, Harini Srinivasan, Jan Paul Buschdorf, John Lalith Charles Richard, Michael J. Meaney, Xiujun Zhang
Publikováno v:
Nucleic Acids Research
Adenosine-to-inosine (A-to-I) RNA editing displays diverse spatial patterns across different tissues. However, the human genome encodes only two catalytically active editing enzymes (ADAR1 and ADAR2), suggesting that other regulatory factors help sha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58316068d4ec2815e21114ed70c69b45
https://doi.org/10.1093/nar/gky615
https://doi.org/10.1093/nar/gky615
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2686 (2008)
Mutations in ATCAY that encodes the brain-specific protein BNIP-H (or Caytaxin) lead to Cayman cerebellar ataxia. BNIP-H binds to glutaminase, a neurotransmitter-producing enzyme, and affects its activity and intracellular localization. Here we descr
Externí odkaz:
https://doaj.org/article/141cbf2a7d65470cac285e71c907cafe
Autor:
Anqi Qiu, Hong Pan, Yue Li, Birit F.P. Broekman, Sarah M Mah, Michael S. Kobor, Helen Chen, Anne Rifkin-Graboi, Lisa M. McEwen, Julia L. MacIsaac, Marielle V. Fortier, Peter D. Gluckman, Yap Seng Chong, Ta Anh Tuan, Joanna D. Holbrook, Li Chen, Seang-Mei Saw, Michael J. Meaney, Jan Paul Buschdorf, Ai Ling Teh, Kenneth Kwek
Publikováno v:
Development and Psychopathology. 27:137-150
Early life environments interact with genotype to determine stable phenotypic outcomes. Here we examined the influence of a variant in the brain-derived neurotropic factor (BDNF) gene (Val66Met), which underlies synaptic plasticity throughout the cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be02e0dcb7b6c3b17286c418cebda720
https://doi.org/10.1017/s0954579414001357
https://doi.org/10.1017/s0954579414001357
Autor:
Walter Stünkel, Jan Paul Buschdorf, Peck Yean Tan, Michael S. Kobor, Louiza Chan, Clara Y. Cheong, Joanna D. Holbrook, Peter D. Gluckman, Mei-Lyn Ong, Keefe Chng, Michael J. Meaney, Sarah M Mah, Julia L. MacIsaac
Publikováno v:
G3: Genes|Genomes|Genetics
The Infinium Human Methylation450 BeadChip Array (Infinium 450K) is a robust and cost-efficient survey of genome-wide DNA methylation patterns. Macaca fascicularis (Cynomolgus macaque) is an important disease model; however, its genome sequence is on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f605a4c3ce9f6b281f863049167a032
https://doi.org/10.1534/g3.114.010967
https://doi.org/10.1534/g3.114.010967
Publikováno v:
Journal of Molecular Endocrinology. 51:59-67
During pregnancy, glucocorticoids transfer environmental signals to the growing brain and its associated neuroendocrine system to modulate their maturation and function during adolescence and adulthood. Increasedin uteroexposure to glucocorticoids is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8592c8d5838ba85020845e8f630d2bf2
https://doi.org/10.1530/jme-12-0218
https://doi.org/10.1530/jme-12-0218
Publikováno v:
Epigenomics. 2:509-512
Keystone Symposia held one of its five global conferences outside of North America in Singapore on 26–30 April 2010, entitled ‘Developmental Origins and Epigenesis in Human Health and Disease’. This was organized by Judith Swain, Peter Gluckman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df77f5ce1873ffd9877285bfaa6e70e4
https://doi.org/10.2217/epi.10.34
https://doi.org/10.2217/epi.10.34
Autor:
Jan Paul Buschdorf, Mei-Lyn Ong, J.L. MacIsaac, Michael J. Meaney, Joanna D. Holbrook, Keefe Chng, Michael S. Kobor, Shirlene X Ong
Publikováno v:
Neuroscience. 318
Birth weight predicts the lifetime risk for psychopathology suggesting that the quality of fetal development influences the predisposition for mental disorders. The connectivity and synaptic network of the hippocampus are implicated in depression, sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933d8da0ad29d8328403a87ae03c702a
https://pubmed.ncbi.nlm.nih.gov/26791528
https://pubmed.ncbi.nlm.nih.gov/26791528
Autor:
Shaillay Kumar Dogra, Mary Ff F. Chong, Yap Seng Chong, Joanna D. Holbrook, Sarah M Mah, Julia L. MacIsaac, Michael S. Kobor, Ai Ling Teh, Sheila J. Barton, Neerja Karnani, Keith M. Godfrey, Seang-Mei Saw, Lisa M. McEwen, Mei-Lyn Ong, Clara Y. Cheong, Walter Stünkel, Jan Paul Buschdorf, Hong Pan, Chee Keong Kwoh, Kenneth Kwek, Peter D. Gluckman, Shu E Soh, Johnny Wong, Li Chen, Michael J. Meaney
Integrating the genotype with epigenetic marks holds the promise of better understanding the biology that underlies the complex interactions of inherited and environmental components that define the developmental origins of a range of disorders. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9577241c6bbfa5747e7be01f9d6bf8
https://eprints.soton.ac.uk/367373/
https://eprints.soton.ac.uk/367373/
