Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Jan-Olof Karlsson"'
Autor:
Madeleine Zetterberg, Anders Behndig, A. Petersen, Dragana Škiljić, Staffan Nilsson, Jan Olof Karlsson
Publikováno v:
Current Eye Research. 43:639-646
Purpose: Protective effects of estradiol against H2O2-induced oxidative stress have been demonstrated in lens epithelial cells. The purpose of this study was to investigate the effects of 17β-estradiol (E2) on the different superoxide dismutase (SOD
Publikováno v:
Mindfulness. 6:1356-1365
An acquired brain injury often leads to long-lasting mental fatigue, which can have a considerable effect on work and social interactions. Fortunately, the Mindfulness-Based Stress Reduction (MBSR) program has been found to alleviate mental fatigue.
Autor:
Therese Carlsson, Jan-Olof Karlsson, Ola Hammarsten, Jakob Himmelman, Per Postgård, Nirmal Kapoor, Mikael Nilsson, Madeleine Nordén Lyckesvärd, Camilla Ingeson-Carlsson, Eva Forssell-Aronsson
Publikováno v:
Experimental cell research. 344(1)
Radiotherapy of thyroid cancer with I-131 is abrogated by inherent loss of radioiodine uptake due to loss of sodium iodide symporter (NIS) expression in poorly differentiated tumor cells. It is also known that ionizing radiation per se down-regulates
Publikováno v:
Acta Ophthalmologica. 70:814-819
Samples of the vitreous were analysed in order to identify changes of soluble proteins in vitreo-retinal disease. The soluble proteins of the vitreous were separated on an anion exchange column (Mono-Q). The degree of neutral proteolytic activity in
Autor:
Roberto Romero, Xiaoyang Wang, Changlian Zhu, Carina Mallard, Pernilla Svedin, Jan-Olof Karlsson, Mats Sandberg, Chunxia Nie, Henrik Hagberg, Risto Lapatto, Malin Gustavsson
Publikováno v:
Annals of Neurology. 61:263-271
OBJECTIVE: Maternal inflammation/infection alone or in combination with birth asphyxia increases the risk for perinatal brain injury. Free radicals are implicated as major mediators of inflammation and hypoxia-ischemia (HI)-induced perinatal brain in
Publikováno v:
Current Eye Research. 32:871-882
This study aimed to investigate redox regulation of the proteasome as well as the effect of proteasome inhibition on intracellular oxidative status and apoptosis.Oxidative stress was induced in cultured human lens epithelial cells (HLECs) and intact
Autor:
Erkki Juronen, Dragana Škiljić, Madeleine Zetterberg, Henrik Zetterberg, Mona Seibt Palmér, Anders Behndig, A. Petersen, Jan-Olof Karlsson, Gunnar Tasa, Staffan Nilsson
Publikováno v:
Ophthalmic genetics. 36(2)
Autor:
Antovan K. Seyedi Honarvar, Anne Peterson, Madeleine Andersson, Johan Sjöstrand, Jan-Olof Karlsson
Publikováno v:
Experimental Eye Research. 76:175-182
Apoptosis has been implied in normal lens development in the embryo as well as in lens fibre differentiation. It has also been suggested to play a role in non-congenital cataract and in the formation of posterior subcapsular opacification, but data o
Autor:
Jan-Olof Karlsson, Xiaoyang Wang, Carina Mallard, Anna-Lena Leverin, Ben A. Bahr, Changlian Zhu, Klas Blomgren, Henrik Hagberg
Publikováno v:
Journal of Biological Chemistry. 276:10191-10198
The relative contributions of apoptosis and necrosis in brain injury have been a matter of much debate. Caspase-3 has been identified as a key protease in the execution of apoptosis, whereas calpains have mainly been implicated in excitotoxic neurona
Publikováno v:
Neonatology. 79:172-179
Caspase-3 is a major effector protease in several apoptotic pathways, but its role in hypoxic-ischemic (HI) brain injury is incompletely understood. Cerebral HI was induced in 7-day-old rats by unilateral carotid artery ligation and exposure to 7.7%