Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jan-Hung Chen"'
Autor:
Jan-Hung Chen, 陳建宏
89
For avoiding the situation that internal electricity demanded increasing rapidly, compatriots have to economize energy first. For decreasing in wasting energy, it depends on economizing energy with everybody in anytime, and then will avoid th
For avoiding the situation that internal electricity demanded increasing rapidly, compatriots have to economize energy first. For decreasing in wasting energy, it depends on economizing energy with everybody in anytime, and then will avoid th
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/06825770419353684678
Publikováno v:
Biophysical Journal. 107(10):2456-2466
The therapeutic efficacy of cytokines is often hampered by severe side effects due to their undesired binding to healthy cells. One strategy for overcoming this obstacle is to tether cytokines to antibodies or antibody fragments for targeted cell del
Autor:
Joseph P. Torella, Christian R. Boehm, Jan-Hung Chen, Jeffrey C. Way, Florian Lienert, Pamela A. Silver
Publikováno v:
Nature Protocols. 9:2075-2089
Recombination-based DNA construction methods, such as Gibson assembly, have made it possible to easily and simultaneously assemble multiple DNA parts, and they hold promise for the development and optimization of metabolic pathways and functional gen
Autor:
Jan-Hung Chen, Christian R. Boehm, Florian Lienert, Pamela A. Silver, Joseph P. Torella, Jeffrey C. Way
Publikováno v:
Nucleic Acids Research
In vitro recombination methods have enabled one-step construction of large DNA sequences from multiple parts. Although synthetic biological circuits can in principle be assembled in the same fashion, they typically contain repeated sequence elements
Autor:
Jan-Hung Chen, Joseph P. Torella, Ryan R. Richardson, Pamela A. Silver, Michael W. Norsworthy, Florian Lienert
Publikováno v:
Nucleic Acids Research
Biological computing circuits can enhance our ability to control cellular functions and have potential applications in tissue engineering and medical treatments. Transcriptional activator-like effectors (TALEs) represent attractive components of synt
Autor:
Xiaofan Jin, Jan-Hung Chen, Zahra Mirzaei, Craig A. Simmons, Kristine Wyss, Cindy Ying Yin Yip
Publikováno v:
Journal of Biomechanics. 45:882-887
Increasing evidence indicates that the progression of calcific aortic valve disease (CAVD) is influenced by the mechanical forces experienced by valvular interstitial cells (VICs) embedded within the valve matrix. The ability of VICs to sense and res
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 31:590-597
Objective— In calcific aortic valve disease, myofibroblasts and activation of the transforming growth factor-β1 (TGF-β1) and Wnt/β-catenin pathways are observed in the fibrosa, the stiffer layer of the leaflet, but their association is unknown.
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:936-942
Objective— Extensive remodeling of the valve ECM in calcific aortic valve sclerosis alters its mechanical properties, but little is known about the impact of matrix mechanics on the cells within the valve interstitium. In this study, the influence
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Introduction: Lesions in calcific aortic valve disease (CAVD) often include osteoblasts and occur preferentially in the natively stiffer fibrosa side of the valve, suggesting roles for osteogenesis and matrix stiffness in CAVD. Valve interstitial cel
Publikováno v:
The FASEB Journal. 24