Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Jan-Hinrich Bräsen"'
Autor:
Sagar Bhayana, Arpita Baisantry, Thomas D. Kraemer, Christoph Wrede, Jan Hegermann, Jan-Hinrich Bräsen, Clemens Bockmeyer, Jan Ulrich Becker, Matthias Ochs, Wilfried Gwinner, Hermann Haller, Anette Melk, Roland Schmitt
Publikováno v:
Journal of Nephropathology, Vol 6, Iss 2, Pp 90-96 (2017)
Background: Mammalian target of rapamycin (mTOR) inhibitors are increasingly used as immunosuppressive agents in kidney transplantation. In the experimental setting it has been shown that mTOR inhibitors promote autophagy, but the concept that this m
Externí odkaz:
https://doaj.org/article/a24dac7d3a9a4cadb7e13dfea9524f98
Autor:
Uwe Hoff, Denise Markmann, Daniela Thurn-Valassina, Melina Nieminen-Kelhä, Zulrahman Erlangga, Jessica Schmitz, Jan Hinrich Bräsen, Klemens Budde, Anette Melk, Björn Hegner
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Interstitial fibrosis and tubular atrophy, a major cause of kidney allograft dysfunction, has been linked to premature cellular senescence. The mTOR inhibitor Rapamycin protects from senescence in experimental models, but its antiproliferative proper
Externí odkaz:
https://doaj.org/article/58d44479abe14d3582555c754b346f0c
Autor:
Marius Andreas Koslik, Justa Friebus-Kardash, Falko Markus Heinemann, Andreas Kribben, Jan Hinrich Bräsen, Ute Eisenberger
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundAntibody-mediated rejection (ABMR) is the main cause of renal allograft loss. The most common treatment strategy is based on plasmapheresis plus the subsequent administration of intravenous immunoglobulin (IVIG). Unfortunately, no approved
Externí odkaz:
https://doaj.org/article/69c2e798fb224389b8f460063a16b268
Autor:
Kirill Kreimann, Mi-Sun Jang, Song Rong, Robert Greite, Sibylle von Vietinghoff, Roland Schmitt, Jan Hinrich Bräsen, Lena Schiffer, Jessica Gerstenberg, Vijith Vijayan, Oliver Dittrich-Breiholz, Li Wang, Christian M. Karsten, Wilfried Gwinner, Hermann Haller, Stephan Immenschuh, Faikah Gueler
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Ischemia reperfusion injury (IRI) is linked with inflammation in kidney transplantation (ktx). The chemokine CXCL13, also known as B lymphocyte chemoattractant, mediates recruitment of B cells within follicles of lymphoid tissues and has recently bee
Externí odkaz:
https://doaj.org/article/b45660c9e05a4c32859baba53d849352
Autor:
Yuliia Yuzefovych, Emilio Valdivia, Song Rong, Franziska Hack, Tamina Rother, Jessica Schmitz, Jan Hinrich Bräsen, Dirk Wedekind, Cyril Moers, Nadine Wenzel, Faikah Gueler, Rainer Blasczyk, Constanca Figueiredo
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Organ gene therapy represents a promising tool to correct diseases or improve graft survival after transplantation. Polymorphic variation of the major histocompatibility complex (MHC) antigens remains a major obstacle to long-term graft survival afte
Externí odkaz:
https://doaj.org/article/03df0d73f4524569bb7b2d84f49f1fc1
Autor:
Margret Patecki, Gabriele Lehmann, Jan Hinrich Bräsen, Jessica Schmitz, Anna Bertram, Lars Daniel Berthold, Hermann Haller, Wilfried Gwinner
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-6 (2017)
Abstract Background Calciphylaxis is a serious complication in patients with chronic kidney disease associated mineral and bone disorder. It can occur in conditions with low and high bone turnover. So far, there are no definite diagnostic and therape
Externí odkaz:
https://doaj.org/article/e95a23bf4eed4a96a8e2a06753a56ad4
Autor:
Li Wang, Vijith Vijayan, Mi-Sun Jang, Anja Thorenz, Robert Greite, Song Rong, Rongjun Chen, Nelli Shushakova, Igor Tudorache, Katja Derlin, Pooja Pradhan, Kukuh Madyaningrana, Nodir Madrahimov, Jan Hinrich Bräsen, Ralf Lichtinghagen, Cees van Kooten, Markus Huber-Lang, Hermann Haller, Stephan Immenschuh, Faikah Gueler
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Ischemia reperfusion injury (IRI) plays a major role in solid organ transplantation. The length of warm ischemia time is critical for the extent of tissue damage in renal IRI. In this experimental study we hypothesized that local release
Externí odkaz:
https://doaj.org/article/3b0f66c1fa424dad859f1b2aa1b0c995
Autor:
Adrian Goldspink, Jessica Schmitz, Olena Babyak, Nicolas Brauns, Julia Milleck, Anne M. Breloh, Susanne V. Fleig, Katarzyna Jobin, Lisa Schwarz, Hermann Haller, Florian Wagenlehner, Jan Hinrich Bräsen, Christian Kurts, Sibylle von Vietinghoff
Publikováno v:
Kidney International.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d5ef07ccd35d9452567b7a1097a19a
https://doi.org/10.1016/j.kint.2023.03.034
https://doi.org/10.1016/j.kint.2023.03.034
Autor:
Jan Hinrich Bräsen
Publikováno v:
Die Pathologie. 43:134-136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37d393e437efb19f6a011525babb480
https://doi.org/10.1007/s00292-022-01148-3
https://doi.org/10.1007/s00292-022-01148-3
Autor:
Shrikant R. Mulay, Jyaysi Desai, Santhosh V. Kumar, Jonathan N. Eberhard, Dana Thomasova, Simone Romoli, Melissa Grigorescu, Onkar P. Kulkarni, Bastian Popper, Volker Vielhauer, Gabriele Zuchtriegel, Christoph Reichel, Jan Hinrich Bräsen, Paola Romagnani, Rostyslav Bilyy, Luis E. Munoz, Martin Herrmann, Helen Liapis, Stefan Krautwald, Andreas Linkermann, Hans-Joachim Anders
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Kidney stone disease is caused by accumulation of oxalate crystals, which trigger tissue injury, inflammation and cell death. Mulay et al. show that crystals induce cell death in the kidney through necroptosis, and propose that this pathway may be a
Externí odkaz:
https://doaj.org/article/4a9913da2de547b6b63c6e14c5eae1e2