Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Jan-Hendrik Niess"'
Autor:
Simon Woelfel, Daniel Junker, Irina Bergamin, Pamela Meyer-Herbon, Roman Stillhard, Nicole Graf, Georg Leinenkugel, Joel Dütschler, Marius König, Livia Kammerlander, Rahel Häuptle, Sarah Zwyssig, Claudia Krieger, Samuel Truniger, Seraina Koller, Katline Metzger-Peter, Nicola Frei, STAR SIGN Study Investigators, Werner C. Albrich, Matthias Friedrich, Christine Bernsmeier, Jan Hendrik Niess, Wolfgang Korte, Justus J. Bürgi, Alex Dulovic, Nicole Schneiderhan-Marra, David Semela, Stephan Brand
Publikováno v:
Vaccines, Vol 12, Iss 11, p 1241 (2024)
Background: Patients with chronic liver disease (CLD) have impaired vaccine immunogenicity and an excess risk of severe COVID-19. While variant-adapted COVID-19 mRNA vaccines are recommended for vulnerable individuals, their efficacy in patients with
Externí odkaz:
https://doaj.org/article/0243ab8f3cae4559b1656d2aae16d763
Autor:
Simon Woelfel, Joel Dütschler, Daniel Junker, Marius König, Georg Leinenkugel, Nicole Graf, Claudia Krieger, Samuel Truniger, Annett Franke, Seraina Koller, Katline Metzger-Peter, Melanie Oberholzer, Nicola Frei, Nora Geissler, Peter Schaub, STAR SIGN Investigators, Werner C. Albrich, Matthias Friedrich, Jan Hendrik Niess, Nicole Schneiderhan-Marra, Alex Dulovic, Wolfgang Korte, Justus J. Bürgi, Stephan Brand
Publikováno v:
Vaccines, Vol 12, Iss 7, p 774 (2024)
Recently updated COVID-19 mRNA vaccines encode the spike protein of the omicron subvariant XBB.1.5 and are recommended for patients with inflammatory bowel disease (IBD) on immunosuppressive treatment. Nonetheless, their immunogenicity in patients wi
Externí odkaz:
https://doaj.org/article/2fdeebad3bb644b1a2cf47e2eefe19a1
Autor:
Oltin-Tiberiu Pop, Anne Geng, Emilio Flint, Arjuna Singanayagam, Caner Ercan, Lucia Possamai, Vishal C. Patel, Patrizia Kuenzler, Marie-Anne Meier, Savas Soysal, Petr Hruz, Otto Kollmar, Kate C. Tatham, Josie K. Ward, Beat Müllhaupt, Achim Weber, Julia Wendon, Jan Hendrik Niess, Markus Heim, David Semela, Christopher Weston, Charalambos G. Antoniades, Luigi Maria Terracciano, Evangelos Triantafyllou, Robert G. Brenig, Christine Bernsmeier
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 17-37 (2023)
Background & Aims: AXL and MERTK expression on circulating monocytes modulated immune responses in patients with cirrhosis (CD14+HLA-DR+AXL+) and acute-on-chronic liver failure (CD14+MERTK+). AXL expression involved enhanced efferocytosis, sustained
Externí odkaz:
https://doaj.org/article/e232e5d8368941d4a69e17e66c9c9998
Autor:
Kentaro Miyamoto, Tomohisa Sujino, Yosuke Harada, Hiroshi Ashida, Yusuke Yoshimatsu, Yuki Yonemoto, Yasuhiro Nemoto, Michio Tomura, Hassan Melhem, Jan Hendrik Niess, Toshihiko Suzuki, Toru Suzuki, Shohei Suzuki, Yuzo Koda, Ryuichi Okamoto, Yohei Mikami, Toshiaki Teratani, Kenji Tanaka, Akihiko Yoshimura, Toshiro Sato, Takanori Kanai
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 113005- (2023)
Summary: The intricate interplay between gut microbes and the onset of experimental autoimmune encephalomyelitis (EAE) remains poorly understood. Here, we uncover remarkable similarities between CD4+ T cells in the spinal cord and their counterparts
Externí odkaz:
https://doaj.org/article/6632c89448fd46648ba14a7d12c1c18d
Publikováno v:
Inflammatory Intestinal Diseases, Vol 6, Iss 3, Pp 165-174 (2021)
Background: TNF inhibitors are relatively safe drugs, but asymptomatic infliximab-induced high serum creatine kinase (CK) levels have been reported in >30% of patients with inflammatory bowel disease (IBD). Whether high serum CK levels are a specific
Externí odkaz:
https://doaj.org/article/f74ef820a8244b9b8f84bac3be88429b
Autor:
Sergi Casadó-Llombart, María Velasco-de Andrés, Cristina Català, Alejandra Leyton-Pereira, Rebeca Gutiérrez-Cózar, Belén Suárez, Noelia Armiger, Esther Carreras, Miriam Esteller, Elena Ricart, Ingrid Ordás, Javier P. Gisbert, María Chaparro, María Esteve, Lucía Márquez, David Busquets, Eva Iglesias, Esther García-Planella, María Dolores Martín-Arranz, Juliane Lohmann, C. Korcan Ayata, Jan Hendrik Niess, Pablo Engel, Julián Panés, Azucena Salas, Eugeni Domènech, Francisco Lozano, ENEIDA Project of GETECCU, Alfredo J. Lucendo, Jordi Guardiola, Xavier Calvet, Lorenzo Olivá́n, Marta Piqueras
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Crohn’s disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) resulting from the interaction of multiple environmental, genetic and immunological factors. CD5 and CD6 are paralogs encoding lymphocyte co-receptors involved i
Externí odkaz:
https://doaj.org/article/f8c831491e61476d9916ae833d60eb38
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Diet and gut microbial metabolites mediate host immune responses and are central to the maintenance of intestinal health. The metabolite-sensing G-protein coupled receptors (GPCRs) bind metabolites and trigger signals that are important for the host
Externí odkaz:
https://doaj.org/article/af3eb9f7d98f4930acdeb9aefa12bdeb
Autor:
Berna Kaya, Cristian Doñas, Philipp Wuggenig, Oscar E. Diaz, Rodrigo A. Morales, Hassan Melhem, Pedro P. Hernández, Tanay Kaymak, Srustidhar Das, Petr Hruz, Yannick Franc, Florian Geier, C. Korcan Ayata, Eduardo J. Villablanca, Jan Hendrik Niess
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107979- (2020)
Summary: Single-nucleotide polymorphisms in the gene encoding G protein-coupled receptor 35 (GPR35) are associated with increased risk of inflammatory bowel disease. However, the mechanisms by which GPR35 modulates intestinal immune homeostasis remai
Externí odkaz:
https://doaj.org/article/ca646a69ee7447feb30e4ca230437f50
Autor:
Jan Hendrik Niess, Rubén Francés
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/fb144284472044dea1a816a37893035f
Publikováno v:
Case Reports in Gastroenterology, Vol 10, Iss 3, Pp 589-595 (2016)
Small intestinal bleeding in Crohn’s disease patients with noncirrhotic portal hypertension and partial portal and superior mesenteric vein thrombosis is a life-threatening event. Here, a case is reported in which treatment with azathioprine may ha
Externí odkaz:
https://doaj.org/article/8fa594a03f7a4c2a80052a75716d8427