Výsledky vyhledávání - "Jan-Erik Westlin"

Boron neutron capture therapy (BNCT) for glioblastoma multiforme: A phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA)

Autor: Jacek Capala, Lars Franzén, Roger Henriksson, Annika Michanek, Sten-Åke Lindahl, A. Tommy Bergenheim, Leif G. Salford, Jan-Erik Westlin, Erik Blomquist

Publikováno v: Radiotherapy and Oncology. 88:183-191

To evaluate the efficacy and safety of boron neutron capture therapy (BNCT) for glioblastoma multiforme (GBM) using a novel protocol for the boronophenylalanine-fructose (BPA-F) infusion.This phase II study included 30 patients, 26-69 years old, with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb1cc3a9909c7502792b54f7eaa9ba5
https://doi.org/10.1016/j.radonc.2006.04.015

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First Clinical Experience with α-Emitting Radium-223 in the Treatment of Skeletal Metastases

Autor: Sten Nilsson, Roy H. Larsen, Gro Salberg, Jan Erik Westlin, Lise Balteskard, Kari W. Borch, Øyvind S. Bruland, Sophie D. Fosså

Publikováno v: Clinical Cancer Research. 11:4451-4459

Purpose: The main goals were to study the safety and tolerability of the α-emitter radium-223 (223Ra) in breast and prostate cancer patients with skeletal metastases. In addition, pain palliation was evaluated. Experimental Design: Fifteen prostate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da80b64369c6e03d6cf8bfa0957edcd9
https://doi.org/10.1158/1078-0432.ccr-04-2244

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Octreoscan in patients with bronchial carcinoid tumours

Autor: Dan Granberg, Eva Tiensuu Janson, Britt Skogseid, Kjell Öberg, Jan-Erik Westlin, Anders Sundin

Publikováno v: Clinical Endocrinology. 59:793-799

Summary objectives Scintigraphy with radiolabelled octreotide (octreoscan) is useful for imaging various neuroendocrine tumours, especially in patients with midgut carcinoids. We were interested in estimating the efficacy of octreoscan for detection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c72b8db0736e3e6dff312311adf58ae0
https://doi.org/10.1046/j.1365-2265.2003.01931.x

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A novel somatostatin conjugate with a high affinity to all five somatostatin receptor subtypes

Autor: Andreas Pfestroff, Jan-Erik Westlin, Rudolf Arnold, Sten Nilsson, Jin Du, Jukka Hiltunen, Ulrich Wulbrand, Marcela Márquez, Martin Feldman, Hans‐Cristophe Fehman, Anders R. Holmberg

Publikováno v: Cancer. 94:1293-1297

BACKGROUND Somatostatin receptors (SRS, five subtypes) are expressed in a variety of human tumors, including most tumors of neuroendocrine origin, breast tumors, certain brain tumors, renal cell tumors, lymphomas, and prostate cancer. Somatostatin (S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7048024725fa083a9005ed3fdbd69561
https://doi.org/10.1002/cncr.10299

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Radiation doses to the cell nucleus in single cells and cells in micrometastases in targeted therapy with 131I labeled ligands or antibodies

Autor: Jan-Erik Westlin, J. Carlsson, Torbjoern Hartman, Hans Lundqvist

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 46:1025-1036

Purpose: The aim of this study was to theoretically investigate how the radiation dose to cell nuclei depends on the subcellular position of 131 I. The influence of the size of the cells and crossfire irradiation in clusters of cells was also studied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae052383d56e1d7edf142a31ef40b5eb
https://doi.org/10.1016/s0360-3016(99)00476-9

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Conjugate Chemistry and Cellular Processing of EGF-Dextran

Autor: Jan-Erik Westlin, Per-Uno Malmström, Lars Gedda, Vladimir Tolmachev, Erik Blomquist, Hans Lundqvist, Åsa Liljegren, Anders Sundin, Qinghai Zhao, Anna Sjöström, Jörgen Carlsson

Publikováno v: Acta Oncologica. 38:313-321

Conjugates with specific binding to the epidermal growth factor receptor, EGFR, of interest for radionuclide based imaging and therapy were prepared using mouse epidermal growth factor, mEGF, and dextran. In one type of conjugate, mEGF was coupled to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0781858405bcf8cb77270e725134ece
https://doi.org/10.1080/028418699431384

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Positron Emission Tomography and Radioimmunotargeting: Aspects of Quantification and Dosimetry

Autor: Jörgen Carlsson, Hans Lundqvist, Anna Lövqvist, Anders Sundin, Jan-Erik Westlin, Harald Schneider, Vladimir Tolmachev, Mark Lubberink

Publikováno v: Acta Oncologica. 38:343-349

Positron emission tomography (PET) is a medical imaging tool with high resolution and good quantitative properties, which makes it suitable for in vivo quantification of radioimmunotargeting agents. Most radionuclides used in radioimmunotherapy have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa41779a8bddf6a7805800ff932fc01
https://doi.org/10.1080/028418699431429

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Limited Tumor Involvement Found at Multiple Endocrine Neoplasia Type I Pancreatic Exploration: Can It Be Predicted by Preoperative Tumor Localization?

Autor: Jonas Rastad, Jan-Erik Westlin, Göran Åkerström, Hampus Eklöf, Anders Elvin, Britt Skogseid, Kjell Öberg, Barbro Eriksson, Claes Juhlin, Eva Tiensuu Janson

Publikováno v: World Journal of Surgery. 22:673-678

Radiologically demonstrable pancreatic endocrine tumors are a frequent requirement for exploration in patients with multiple endocrine neoplasia type I (MEN-I). Such delayed intervention is accompanied by a 30% to 50% incidence of pancreatic endocrin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4b4c20929d30fa2345f785e5eeb665
https://doi.org/10.1007/s002689900451

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Expression of epidermal growth factor receptor in urinary bladder cancer metastases

Autor: P.-U. Malmström, Anna Sjöström, Kenneth Wester, Jan-Erik Westlin, Anders Holmberg, Christer Busch, Peter Bue, S. Nilsson, Jörgen Carlsson

Publikováno v: International Journal of Cancer. 76:189-193

Bladder cancers frequently exhibit an increased number of epidermal growth factor receptors (EGFR) in comparison to normal urothelium. The EGFR could potentially be a target for toxic conjugates. The aim of our study was to compare the expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9d08ced89d1d1e63a65fc008a397c62
https://doi.org/10.1002/(sici)1097-0215(19980413)76:2<189::aid-ijc4>3.0.co

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