Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jan-Erik Lindgren"'
Autor:
Bo Holmstedt, Jan-Erik Lindgren
Publikováno v:
Ciba Foundation Symposium 26-The Poisoned Patient: The Role of the Laboratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d56b72b607d22191bea35d08bdd4c57
https://doi.org/10.1002/9780470720080.ch7
https://doi.org/10.1002/9780470720080.ch7
Autor:
Kurt Leander, Bill Martin, Marianne Nordqvist, Michael Binder, Stig Agurell, Jan-Erik Lindgren
Publikováno v:
Journal of Pharmacy and Pharmacology. 28:275-279
Cannabidiol (CBD) was metabolized in vitro by rat liver enzymes. Unchanged CBD and eight monohydroxylated metabolites were isolated and positively identified. As previously reported, 7-hydroxy-CBD was the major metabolite. The second most abundant me
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 12:367-380
In two different absorption studies, quantitative correlations between the in vitro dissolution rate and the bioavailability have been shown after single administration of various tablet compositions of alaproclate hydrochloride to healthy subjects.
Autor:
L. Rivier, Richard Evans Schultes, Timothy Plowman, Bo Holmstedt, Jan-Erik Lindgren, Oscar Tovar
Publikováno v:
Botanical Museum leaflets, Harvard University. 28:215-234
Publikováno v:
Botanical Museum leaflets, Harvard University. 25:273-287
Publikováno v:
Biochemical Pharmacology. 23:1163-1172
Δ1-Tetrahydrocannabinol (Δ1-THC) administered i.v. (1 mg/kg) to anaesthetized rats with cannulated bile ducts is rapidly eliminated as metabolites in the bile. 60–70 per cent in 6 hr. In comparison with the slow excretion via faeces an extensive
Single dose kinetics of deuterium labelled Δ1-tetrahydrocannabinol in heavy and light cannabis users
Publikováno v:
Biological Mass Spectrometry. 9:6-10
Deuterium labelled delta 1-tetrahydrocannabinol was administered intravenously (5.0 mg) and by smoking (10.0 mg) to five heavy and four light marihuana users. All subjects smoked an estimated amount of 8.6-9.9 mg delta 1-tetrahydrocannabinol. The pla
Publikováno v:
Helvetica Chimica Acta. 57:1626-1641
The 100-MHz-NMR-spectra of 11 side chain hydroxylated derivatives of cannabidiol (1), Δ6-tetrahydrocannabinol (2) and cannabinol (3) were analysed for signals specific for the position of hydroxyl groups. The mass spectra of these compounds and thei
Publikováno v:
Journal of Pharmacy and Pharmacology. 28:603-608
The metabolism of cannabidiol (CBD) was studied in vitro using a 10 000 g supernatant from rat liver. After removal of unchanged CBD and its monohydroxylated metabolites, a polar fraction remained from which ten dioxygenated metabolites were isolated
Publikováno v:
Acta Chemica Scandinavica. 14:829-835