Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jan van der Vliet"'
Autor:
Giustina Ferone, Ji-Ying Song, Oscar Krijgsman, Jan van der Vliet, Miranda Cozijnsen, Ekaterina A. Semenova, David J. Adams, Daniel Peeper, Anton Berns
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3837-3850.e3 (2020)
Summary: Fibroblast growth factor receptor 1 (FGFR1) is frequently amplified in human small-cell lung cancer (SCLC), but its contribution to SCLC and other lung tumors has remained elusive. Here, we assess the tumorigenic capacity of constitutive-act
Externí odkaz:
https://doaj.org/article/ee99afba6a11476186cf223892db7b66
Autor:
Franziska Böttger, Ekaterina A. Semenova, Ji-Ying Song, Giustina Ferone, Jan van der Vliet, Miranda Cozijnsen, Rajith Bhaskaran, Lorenzo Bombardelli, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Anton Berns
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3345-3358.e4 (2019)
Summary: Small-cell lung cancer is the most aggressive type of lung cancer, characterized by a remarkable response to chemotherapy followed by development of resistance. Here, we describe SCLC subtypes in Mycl- and Nfib-driven GEMM that include CDH1-
Externí odkaz:
https://doaj.org/article/3c07f3bfb67240a8bf9f9b7794cc555b
Autor:
Ekaterina A. Semenova, Min-chul Kwon, Kim Monkhorst, Ji-Ying Song, Rajith Bhaskaran, Oscar Krijgsman, Thomas Kuilman, Dennis Peters, Wieneke A. Buikhuisen, Egbert F. Smit, Colin Pritchard, Miranda Cozijnsen, Jan van der Vliet, John Zevenhoven, Jan-Paul Lambooij, Natalie Proost, Erwin van Montfort, Arno Velds, Ivo J. Huijbers, Anton Berns
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 631-643 (2016)
Small cell lung cancer (SCLC) is an aggressive neuroendocrine tumor, and no effective treatment is available to date. Mouse models of SCLC based on the inactivation of Rb1 and Trp53 show frequent amplifications of the Nfib and Mycl genes. Here, we re
Externí odkaz:
https://doaj.org/article/0c5e4b5dae114c238369da8b5e06aff1
Autor:
Cathy Cailotto, Pedro J Gomez-Pinilla, Léa M Costes, Jan van der Vliet, Martina Di Giovangiulio, Andrea Némethova, Gianluca Matteoli, Guy E Boeckxstaens
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87785 (2014)
BACKGROUND: Electrical stimulation of the vagus nerve suppresses intestinal inflammation and normalizes gut motility in a mouse model of postoperative ileus. The exact anatomical interaction between the vagus nerve and the intestinal immune system re
Externí odkaz:
https://doaj.org/article/9c920ff3591c4d52b2a1e28fb8c61055
Autor:
Léa M M Costes, Jan van der Vliet, Giovanna Farro, Gianluca Matteoli, Sjoerd H W van Bree, Brenda J Olivier, Martijn A Nolte, Guy E Boeckxstaens, Cathy Cailotto
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102211 (2014)
Postoperative ileus is characterized by a transient impairment of the gastrointestinal motility after abdominal surgery. The intestinal inflammation, triggered by handling of the intestine, is the main factor responsible for the prolonged dysmotility
Externí odkaz:
https://doaj.org/article/9108a0fda1ef449aa68e087e8af1cca8
Autor:
Cathy Cailotto, Jun Lei, Jan van der Vliet, Caroline van Heijningen, Corbert G van Eden, Andries Kalsbeek, Paul Pévet, Ruud M Buijs
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5650 (2009)
BACKGROUND:The biological clock, located in the hypothalamic suprachiasmatic nucleus (SCN), controls the daily rhythms in physiology and behavior. Early studies demonstrated that light exposure not only affects the phase of the SCN but also the funct
Externí odkaz:
https://doaj.org/article/b26fbe3a55d944009041eb536b6cb7da
Autor:
Andries Kalsbeek, Ewout Foppen, Ingrid Schalij, Caroline Van Heijningen, Jan van der Vliet, Eric Fliers, Ruud M Buijs
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3194 (2008)
The mammalian biological clock, located in the hypothalamic suprachiasmatic nuclei (SCN), imposes its temporal structure on the organism via neural and endocrine outputs. To further investigate SCN control of the autonomic nervous system we focused i
Externí odkaz:
https://doaj.org/article/5de97b57f5314f0ab1537a5aa553b8fd
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3152 (2008)
BACKGROUND: Recently the vagal output of the central nervous system has been shown to suppress the innate immune defense to pathogens. Here we investigated by anatomical and physiological techniques the communication of the brain with the spleen and
Externí odkaz:
https://doaj.org/article/2cc0dbd97aa74dd4b8269bf837fd4d15
Autor:
Anton Berns, Lodewyk F. A. Wessels, Hilda de Vries, Miranda Cozijnsen, Jan van der Vliet, Marieke van de Ven, Natalie Proost, Nanne Aben, Ana Teresa Avelar, Remco Nagel
Supplementary figure 4. Cell viability data based to generate the synergy plots in Figures 2 and 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01456a994a6da6126e64204a68188bf0
https://doi.org/10.1158/1535-7163.22509532
https://doi.org/10.1158/1535-7163.22509532
Autor:
Anton Berns, Lodewyk F. A. Wessels, Hilda de Vries, Miranda Cozijnsen, Jan van der Vliet, Marieke van de Ven, Natalie Proost, Nanne Aben, Ana Teresa Avelar, Remco Nagel
Supplementary figure 1A. Sequencing tracks of a part of the Zwilch gene targeted by a first unique sgRNA, with the wildtype sequence (top) and sgRNA treated sequence (bottom) shown. B. Tide analysis showing editing efficiency of the first Zwilch targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ef73071c7d28e426d7d94709434aa2
https://doi.org/10.1158/1535-7163.22509544.v1
https://doi.org/10.1158/1535-7163.22509544.v1