Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jan van den Brulle"'
Autor:
Chenxi Qiu, Olivia C Erinne, Jui M Dave, Ping Cui, Huiyan Jin, Nandhini Muthukrishnan, Leung K Tang, Sabareesh Ganesh Babu, Kenny C Lam, Paul J Vandeventer, Ralf Strohner, Jan Van den Brulle, Sing-Hoi Sze, Craig D Kaplan
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007158 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1006321.].
Externí odkaz:
https://doaj.org/article/5462e52110c746c599ac8e74c725634e
Autor:
Chenxi Qiu, Olivia C Erinne, Jui M Dave, Ping Cui, Huiyan Jin, Nandhini Muthukrishnan, Leung K Tang, Sabareesh Ganesh Babu, Kenny C Lam, Paul J Vandeventer, Ralf Strohner, Jan Van den Brulle, Sing-Hoi Sze, Craig D Kaplan
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006321 (2016)
The active sites of multisubunit RNA polymerases have a "trigger loop" (TL) that multitasks in substrate selection, catalysis, and translocation. To dissect the Saccharomyces cerevisiae RNA polymerase II TL at individual-residue resolution, we quanti
Externí odkaz:
https://doaj.org/article/0093dec7c23e444383965144785bda19
Autor:
Jan Van den Brulle, Markus Fischer, Thomas Langmann, Gudrun Horn, Thomas Waldmann, Stefan Arnold, Markus Fuhrmann, Octavian Schatz, Tim O'Connell, Daniela O'Connell, Alexandra Auckenthaler, Heinz Schwer
Publikováno v:
BioTechniques, Vol 45, Iss 3, Pp 340-343 (2008)
Externí odkaz:
https://doaj.org/article/a9608e6bef584c85927d6a4caa8b8f81
Autor:
Emmanuel Donnadieu, Maik Luu, Miriam Alb, Brigitte Anliker, Silvia Arcangeli, Chiara Bonini, Biagio De Angelis, Rashmi Choudhary, David Espie, Anne Galy, Cam Holland, Zoltán Ivics, Chahrazade Kantari-Mimoun, Marie Jose Kersten, Ulrike Köhl, Chantal Kuhn, Bruno Laugel, Franco Locatelli, Ibtissam Marchiq, Janet Markman, Marta Angiola Moresco, Emma Morris, Helene Negre, Concetta Quintarelli, Michael Rade, Kristin Reiche, Matthias Renner, Eliana Ruggiero, Carmen Sanges, Hans Stauss, Maria Themeli, Jan Van den Brulle, Michael Hudecek, Monica Casucci
Publikováno v:
Donnadieu, E, Luu, M, Alb, M, Anliker, B, Arcangeli, S, Bonini, C, de Angelis, B, Choudhary, R, Espie, D, Galy, A, Holland, C, Ivics, Z, Kantari-Mimoun, C, Kersten, M J, Köhl, U, Kuhn, C, Laugel, B, Locatelli, F, Marchiq, I, Markman, J, Moresco, M A, Morris, E, Negre, H, Quintarelli, C, Rade, M, Reiche, K, Renner, M, Ruggiero, E, Sanges, C, Stauss, H, Themeli, M, van den Brulle, J, Hudecek, M & Casucci, M 2022, ' Time to evolve : predicting engineered T cell-associated toxicity with next-generation models ', Journal for Immunotherapy of Cancer, vol. 10, no. 5 . https://doi.org/10.1136/jitc-2021-003486
Despite promising clinical results in a small subset of malignancies, therapies based on engineered chimeric antigen receptor and T-cell receptor T cells are associated with serious adverse events, including cytokine release syndrome and neurotoxicit
Autor:
Kenny C. Lam, Nandhini Muthukrishnan, Jui M. Dave, Huiyan Jin, Sing-Hoi Sze, Jan Van den Brulle, Craig D. Kaplan, Paul J. Vandeventer, Ping Cui, Chenxi Qiu, Ralf Strohner, Sabareesh Ganesh Babu, Leung K. Tang, Olivia C. Erinne
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007158 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1006321.].
Autor:
Jan Van den Brulle, Paul J. Vandeventer, Ping Cui, Kenny C. Lam, Ralf Strohner, Nandhini Muthukrishnan, Sing-Hoi Sze, Olivia C. Erinne, Huiyan Jin, Craig D. Kaplan, Sabareesh Ganesh Babu, Leung K. Tang, Jui M. Dave, Chenxi Qiu
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 11, p e1006321 (2016)
PLoS Genetics, Vol 12, Iss 11, p e1006321 (2016)
The active sites of multisubunit RNA polymerases have a “trigger loop” (TL) that multitasks in substrate selection, catalysis, and translocation. To dissect the Saccharomyces cerevisiae RNA polymerase II TL at individual-residue resolution, we qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0783d633b9e30bb8c59c2c1700e30f
Autor:
Heinz Schwer, Jan Van den Brulle, Karin Weigelt, Yana Walczak, Rudolf Fuchshofer, Stefanie Ebert, Marcus Karlstetter, Thomas Langmann
Publikováno v:
The Journal of Immunology. 185:3379-3390
Microgliosis is a common phenomenon in neurodegenerative disorders, including retinal dystrophies. To identify candidate genes involved in microglial activation, we used DNA-microarray analysis of retinal microglia from wild-type and retinoschisin-de
Autor:
Markus Fischer, Felix Rohdich, Adelbert Bacher, Sabine Saller, Mark Cushman, Wolfgang Eisenreich, Johannes Kaiser, Boris Illarionov, Jan Van den Brulle
Publikováno v:
Analytical Biochemistry. 365:52-61
3,4-Dihydroxy-2-butanone 4-phosphate synthase, 6,7-dimethyl-8-ribityllumazine synthase, and riboflavin synthase of the riboflavin biosynthetic pathway are potential targets for novel antiinfective drugs. This article describes a platform for high-thr
Autor:
David R. Cox, Irene Ni, Guido Cappuccilli, Li Mei, Wenwu Zhai, Jan Van den Brulle, William J.J. Finlay, Thomas Van Blarcom, Yasmina Noubia Abdiche, Jacob Glanville, Kevin Lindquist, Purnima Sundar, Jaume Pons, Dilduz Telman, Arvind Rajpal, Markus Fuhrmann, Ralf Strohner
Publikováno v:
Journal of molecular biology. 412(1)
We present a method for synthetic antibody library generation that combines the use of high-throughput immune repertoire analysis and a novel synthetic technology. The library design recapitulates positional amino acid frequencies observed in natural
Autor:
Alexandra Auckenthaler, Jan Van den Brulle, Heinz Schwer, Markus Fuhrmann, Thomas Langmann, Thomas Waldmann, Daniela O'Connell, Stefan Arnold, Gudrun Horn, Octavian Schatz, Timothy O'connell, Markus Fischer
Publikováno v:
BioTechniques. 45(3)
Jan Van den Brulle1#, Markus Fischer2#, Thomas Langmann3#, Gudrun Horn1, Thomas Waldmann1, Stefan Arnold1, Markus Fuhrmann1, Octavian Schatz1, Tim O Connell1, Daniela O Connell1, Alexandra Auckenthaler1, and Heinz Schwer1* #These authors contributed