Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jan Zavada"'
Autor:
Yoshinori Ino, Rie Yamazaki-Itoh, Seiji Oguro, Kazuaki Shimada, Tomoo Kosuge, Jan Zavada, Yae Kanai, Nobuyoshi Hiraoka
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55146 (2013)
An adequate level of arginine in the tissue microenvironment is essential for T cell activity and survival. Arginine levels are regulated by the arginine-catabolizing enzyme, arginase (ARG). It has been reported that arginase II (ARG2), one of two AR
Externí odkaz:
https://doaj.org/article/5f03462e5b9844fca1afc828de54309b
Autor:
Christine Lohse, Eugene D. Kwon, Jan Zavada, John C. Cheville, R. Houston Thompson, Yuri Sheinin, Bradley C. Leibovich
Publikováno v:
Journal of Clinical Oncology. 25:4757-4764
Purpose Expression of carbonic anhydrase IX (CAIX) has been reported to be an independent predictor of outcome and is being investigated as a therapeutic target for patients with clear cell renal cell carcinoma (ccRCC). We attempted to validate the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7aa00630a797dc1c3a9bae32f47b2f
https://doi.org/10.1200/jco.2007.12.1087
https://doi.org/10.1200/jco.2007.12.1087
Publikováno v:
British Journal of Cancer
Tumour-associated protein carbonic anhydrase IX (CA IX) has two major forms. One is a cell-associated, transmembrane protein seen on Western blots as a twin band of 54/58 kDa, expressed in gastric mucosa and in several types of cancer. The other is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c98927b3b41683b03d31849eea6addc
https://doi.org/10.1038/sj.bjc.6601264
https://doi.org/10.1038/sj.bjc.6601264
Autor:
Seppo Parkkila, Silvia Pastorekova, Jaromir Pastorek, Milota Kaluzová, Július Rajčáni, Stefan Kaluz, Adrian Chrastina, Jan Zavada
Publikováno v:
International Journal of Cancer. 105:873-881
Carbonic anhydrase IX (CA IX) is frequently expressed in human carcinomas and absent from the corresponding normal tissues. Strong induction by tumor hypoxia predisposes CA IX to serve as a target for cancer diagnostics and therapy. Here we evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83818e0dc6c18ccd5a592c5742cefcbc
https://doi.org/10.1002/ijc.11142
https://doi.org/10.1002/ijc.11142
Autor:
Seppo Parkkila, Zuzana Závadová, Marta Ortova Gut, Jan Svoboda, Silvia Pastorekova, Ivan Horak, Zdeòka Vernerová, Jaromir Pastorek, Klaus-Peter Knobeloch, Bertram Wiedenmann, Michael Höcker, Jan Zavada, Adriana Gibadulinova, Elvira Rohde, Tuomo J. Karttunen
Publikováno v:
Gastroenterology. 123:1889-1903
Background & Aims: Carbonic anhydrase (CA) IX is a highly active enzyme with adhesion capacity that is functionally implicated in acid-base balance and intercellular communication. It is normally present in basolateral membranes of gastrointestinal e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e5f9c6962b7d4d0496368573750fc0
https://doi.org/10.1053/gast.2002.37052
https://doi.org/10.1053/gast.2002.37052
Publikováno v:
British Journal of Cancer
MN/CA IX is a cell surface protein, strongly associated with several types of human carcinomas. It exerts activity of carbonic anhydrase and capacity of binding to cell surface receptors. In the present work, we used affinity purified MN/CA IX protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e7028f62aaf62485c21f719fd3b75e
http://europepmc.org/articles/PMC2363230
http://europepmc.org/articles/PMC2363230
Publikováno v:
Journal of Clinical Oncology. 26:3809-3811
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4012b32e3ffd22341ad8df64e4b85741
https://doi.org/10.1200/jco.2008.17.6511
https://doi.org/10.1200/jco.2008.17.6511
Autor:
Bradley C. Leibovich, Yuri Sheinin, Christine M. Lohse, R. Houston Thompson, John C. Cheville, Jan Zavada, Eugene D. Kwon
Publikováno v:
Journal of Clinical Oncology. 26:3107-3109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ace1a456ddb5046100bd28c53288f422
https://doi.org/10.1200/jco.2008.16.2164
https://doi.org/10.1200/jco.2008.16.2164
Autor:
Maritza Martel, Jan Zavada, David L. Rimm, Jia Li, Lyndsay Harris, Kimberley Lezon-Geyda, Catherine A.W. Sullivan, Veronique Neumeister, Peter M. Glazer, Robert Lindner, David Tuck
Publikováno v:
Breast cancer research and treatment. 136(1)
The purpose of this study is to explore the relationship between tumor hypoxia assessed by CA IX protein expression and loss of BRCA1 function in triple negative breast cancer (TNBC). Protein expression of CA IX and BRCA1 was evaluated by AQUA™ tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768c4dadcf93a02e7bb534f98866d6c3
https://pubmed.ncbi.nlm.nih.gov/22976806
https://pubmed.ncbi.nlm.nih.gov/22976806
Autor:
Jan Zavada, Tomoo Kosuge, Seiji Oguro, Yae Kanai, Kazuaki Shimada, Yoshinori Ino, Rie Yamazaki-Itoh, Nobuyoshi Hiraoka
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e55146 (2013)
PLoS ONE, Vol 8, Iss 2, p e55146 (2013)
An adequate level of arginine in the tissue microenvironment is essential for T cell activity and survival. Arginine levels are regulated by the arginine-catabolizing enzyme, arginase (ARG). It has been reported that arginase II (ARG2), one of two AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a294760f5bdd644f8cd5a8d4e37be16
https://pubmed.ncbi.nlm.nih.gov/23424623
https://pubmed.ncbi.nlm.nih.gov/23424623