Higher GABA concentration in the medial prefrontal cortex of Type 2 diabetes patients is associated with episodic memory dysfunction

Autor: David G. Norris, Evrim Anadol-Schmitz, Sofiya Gancheva, Jan Willem Thielen, Indira Tendolkar, Michael Roden, Maria Apostolopoulou, Donghyun Hong, Bixia Chen, Seyedmorteza Rohani Rankouhi

Publikováno v: Hum Brain Mapp
Human brain mapping, 40(14), 4287-4295. Wiley-Liss Inc.
Human Brain Mapping, 40, 4287-4295
Human Brain Mapping, 40, 14, pp. 4287-4295

Contains fulltext : 209018.pdf (Publisher’s version ) (Closed access) Type 2 diabetes (T2D) is associated with an accelerated episodic memory decline, but the underlying pathophysiological mechanisms are not well understood. Hallmarks of T2D compri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5633f8262c45a97f00f7b6f683857129
https://doi.org/10.1002/hbm.24702

Sleep supports selective retention of associative memories based on relevance for future utilization.

Autor: Eelco V van Dongen, Jan-Willem Thielen, Atsuko Takashima, Markus Barth, Guillén Fernández

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43426 (2012)

An outstanding question is whether memory consolidation occurs passively or involves active processes that selectively stabilize memories based on future utility. Here, we differentially modulated the expected future relevance of two sets of picture-

Externí odkaz: https://doaj.org/article/b5c090dc591a43a99c35dd58a6680c54

A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T

Autor: Jan Willem Thielen, Jack J.A. van Asten, David G. Norris, Donghyun Hong, Seyedmorteza Rohani Rankouhi

Publikováno v: PLoS ONE
PLoS One, 14, 10, pp. 1-19
PLoS ONE, 14(10):e0223702. Public Library of Science
PLoS One, 14, 1-19
PLoS ONE, Vol 14, Iss 10, p e0223702 (2019)

γ-Aminobutyric acid (GABA), the major inhibitory neurotransmitter, is challenging to measure using proton spectroscopy due to its relatively low concentration, J-coupling and overlapping signals from other metabolites. Currently, the prevalent metho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04fd1cd7ca98e6f1a4fbc4e00962827
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/215671

Transient relay function of midline thalamic nuclei during long-term memory consolidation in humans

Autor: Jan Willem Thielen, Indira Tendolkar, Guillén Fernández, Femke Rutters, Atsuko Takashima

Publikováno v: Learning and Memory, 22(10), 527-531. Cold Spring Harbor Laboratory Press
Thielen, J W, Takashima, A, Rutters, F, Tendolkar, I & Fernandez, G 2015, ' Transient relay function of midline thalamic nuclei during long-term memory consolidation in humans ', Learning and Memory, vol. 22, no. 10, pp. 527-531 . https://doi.org/10.1101/lm.038372.115
Learning & Memory, 22, 527-531
Learning & Memory, 22, 10, pp. 527-531

Contains fulltext : 154335.pdf (Publisher’s version ) (Open Access) To test the hypothesis that thalamic midline nuclei play a transient role in memory consolidation, we reanalyzed a prospective functional MRI study, contrasting recent and progress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a91e4596073549499ff9028a2b0369
https://research.vumc.nl/en/publications/1f828b6c-26ab-4e05-9106-0f4375ce09d2