Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jan Willem Alffenaar"'
Autor:
Giovanni Battista Migliori, Simon Tiberi, Alimuddin Zumla, Eskild Petersen, Jeremiah Muhwa Chakaya, Christian Wejse, Marcela Muñoz Torrico, Raquel Duarte, Jan Willem Alffenaar, H. Simon Schaaf, Ben J. Marais, Daniela Maria Cirillo, Riccardo Alagna, Adrian Rendon, Emanuele Pontali, Alberto Piubello, José Figueroa, Gabriella Ferlazzo, Alberto García-Basteiro, Rosella Centis, Dina Visca, Lia D’Ambrosio, Giovanni Sotgiu, T. Abu Arkub, O.W. Akkerman, A. Aleksa, E. Belilovski, E. Bernal, F-X. Blanc, M. Boeree, S. Borisov, J. Bruchfeld, J. Cadiñanos Loidi, J.A. Caminero, A.C. Carvalho, J.J. Cebrian Gallardo, Charalampos, E. Danila, L. Davies Forsman, J. Denholm, K. Dheda, R. Diel, S. Diktanas, C. Dobler, M. Enwerem, S. Esposito, N. Escobar Salinas, A. Filippov, B. Formenti, J.M. García García, D. Goletti, R. Gomez Rosso, G. Gualano, P. Isaakidis, A. Kaluzhenina, S. Koirala, L. Kuksa, H. Kunst, Y. Li, C. Magis-Escurra, V. Manfrin, S. Manga, K. Manika, V. Marchese, E. Martínez Robles, A. Maryandyshev, A. Matteelli, A. Mariani, J. Mazza-Stalder, F. Mello, L. Mendoza, A. Mesi, S. Miliauskas, H. Mustafa Hamdan, N. Ndjeka, M. Nieto Marcos, T.H.M. Ottenhoff, D.J. Palmero, F. Palmieri, A. Papavasileiou, M.C. Payen, A. Pontarelli, M. Pretti Dalcolmo, S. Quirós Fernandez, R. Romero, D. Rossato Silva, A.P. Santos, B. Seaworth, M. Sinitsyn, A. Skrahina, I. Solovic, A. Spanevello, M. Tadolini, C. Torres, Z. Udwadia, M. van den Boom, G.V. Volchenkov, A. Yedilbayev, R. Zaleskis, J.P. Zellweger
Publikováno v:
International Journal of Infectious Diseases, Vol 92, Iss , Pp S15-S25 (2020)
The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-
Externí odkaz:
https://doaj.org/article/5bf1bcbfae704a81a73f0b7fa43be20d
Autor:
Sandor-Adrian Klis, Ymkje Stienstra, Kabiru M. Abass, Justice Abottsi, Samuel O. Mireku, Jan-Willem Alffenaar, Tjip S. van der Werf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Clarithromycin extended-release (CLA-ER) was used as companion drug to rifampicin (RIF) for Mycobacterium ulcerans infection in the intervention arm of a WHO drug trial. RIF enhances CYP3A4 metabolism, thereby reducing CLA serum concentratio
Externí odkaz:
https://doaj.org/article/f223ca5818294846b68aae5a309d86f3
Autor:
Sainan Wang, Lina Davies Forsman, Chunhua Xu, Haoyue Zhang, Yue Zhu, Ge Shao, Shanshan Wang, Jiayi Cao, Haiyan Xiong, Katarina Niward, Thomas Schön, Judith Bruchfeld, Limei Zhu, Jan-Willem Alffenaar, Yi Hu
Publikováno v:
International Journal of Infectious Diseases, Vol 140, Iss , Pp 62-69 (2024)
Objectives: This study aimed to investigate the association between drug exposure and adverse events (AEs) during the standardized multidrug-resistant tuberculosis (MDR-TB) treatment, as well as to identify predictive drug exposure thresholds. Method
Externí odkaz:
https://doaj.org/article/21c39d5198aa4b1b8602c78b0aae8246
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 818 (2024)
Multidrug-resistant tuberculosis (MDR-TB) is a global health concern. Standard treatment involves the use of linezolid, a repurposed oxazolidinone. It is associated with severe adverse effects, including myelosuppression and mitochondrial toxicity. A
Externí odkaz:
https://doaj.org/article/2669d17c00f048fb9977a6e613b8ad20
Autor:
Joanitah Nalunjogi, Sergio Mucching-Toscano, Jean Pierre Sibomana, Rosella Centis, Lia D'Ambrosio, Jan-Willem Alffenaar, Justin Denholm, François-Xavier Blanc, Sergey Borisov, Edvardas Danila, Raquel Duarte, José-María García-García, Delia Goletti, Catherine W.M. Ong, Adrian Rendon, Tania A. Thomas, Simon Tiberi, Martin van den Boom, Giovanni Sotgiu, Giovanni Battista Migliori
Publikováno v:
International Journal of Infectious Diseases, Vol 130, Iss , Pp S25-S29 (2023)
Objectives: Although evidence is growing on the overall impact of the COVID-19 pandemic on tuberculosis (TB) services, global studies based on national data are needed to better quantify the extent of the impact and the countries’ preparedness to t
Externí odkaz:
https://doaj.org/article/4ca2b005bd734a77b02258a4c84718dd
Autor:
Ge Shao, Ziwei Bao, Lina Davies Forsman, Jakob Paues, Jim Werngren, Katarina Niward, Thomas Schön, Judith Bruchfeld, Jan-Willem Alffenaar, Yi Hu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Aims: Bedaquiline is now recommended to all patients in the treatment of multidrug-resistant tuberculosis (MDR-TB) using standard dosing regimens. As the ability to measure blood drug concentrations is very limited, little is known about drug exposur
Externí odkaz:
https://doaj.org/article/79f766a20443497e9ae54a167575c803
Autor:
Haoyue Zhang, Yuying He, Lina Davies Forsman, Jakob Paues, Jim Werngren, Katarina Niward, Thomas Schön, Judith Bruchfeld, Jan-Willem Alffenaar, Yi Hu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Background: The pharmacokinetic/pharmacodynamics (PK/PD) target derived from the hollow-fiber system model for linezolid for treatment of the multidrug-resistant tuberculosis (MDR-TB) requires clinical validation. Therefore, this study aimed to devel
Externí odkaz:
https://doaj.org/article/53c438e7ef114510b2818aa5a1cad78b
Autor:
Mohammad Javad Nasiri, Moein Zangiabadian, Erfan Arabpour, Sirus Amini, Farima Khalili, Rosella Centis, Lia D'Ambrosio, Justin T. Denholm, H. Simon Schaaf, Martin van den Boom, Xhevat Kurhasani, Margareth Pretti Dalcolmo, Seif Al-Abri, Jeremiah Chakaya, Jan-Willem Alffenaar, Onno Akkerman, Denise Rossato Silva, Marcela Muňoz-Torrico, Barbara Seaworth, Emanuele Pontali, Laura Saderi, Simon Tiberi, Alimuddin Zumla, Giovanni Battista Migliori, Giovanni Sotgiu
Publikováno v:
International Journal of Infectious Diseases, Vol 124, Iss , Pp S90-S103 (2022)
Introduction: Multidrug-resistant tuberculosis (MDR-TB) is a life-threatening condition needing long poly-chemotherapy regimens. As no systematic reviews/meta-analysis is available to comprehensively evaluate the role of delamanid (DLM), we evaluated
Externí odkaz:
https://doaj.org/article/1013ff3992ee4358b5b64e226acdf446
Autor:
Jingjing Hou, Debbie Marriott, Dario Cattaneo, Sophie Stocker, Jana Stojanova, Jan-Willem Alffenaar, Chenlin Xiao, Yichang Zhao, Hui Gong, Miao Yan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objectives: The current practice of therapeutic drug monitoring (TDM) in Asia is poorly documented. Our aim was to capture and describe TDM services delivered in hospitals across Asia, including aspects such as assay availability, interpretation of r
Externí odkaz:
https://doaj.org/article/11563fead7984f66ac4494a1760415dc
Autor:
Tawanda Gumbo, Carleton M. Sherman, Devyani Deshpande, Jan-Willem Alffenaar, Shashikant Srivastava
Publikováno v:
International Journal of Infectious Diseases, Vol 104, Iss , Pp 680-684 (2021)
Background: Faropenem (F), an orally bioavailable β-lactam, kills Mycobacterium tuberculosis (Mtb) without the help of a β-lactamase inhibitor. This study explored the sterilizing effect of adding F once or twice daily to a linezolid (L) plus pyraz
Externí odkaz:
https://doaj.org/article/f3407f9be2194bff8b6b6e1f295895fd