Výsledky vyhledávání - "Jan Van der Goten"

Akademický článek

Integrated miRNA and mRNA expression profiling in inflamed colon of patients with ulcerative colitis.

Autor: Jan Van der Goten, Wiebe Vanhove, Katleen Lemaire, Leentje Van Lommel, Kathleen Machiels, Willem-Jan Wollants, Vicky De Preter, Gert De Hertogh, Marc Ferrante, Gert Van Assche, Paul Rutgeerts, Frans Schuit, Séverine Vermeire, Ingrid Arijs

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e116117 (2014)

BACKGROUND: Ulcerative colitis (UC) is associated with differential colonic expression of genes involved in immune response (e.g. IL8) and barrier integrity (e.g. cadherins). MicroRNAs (miRNAs) are regulators of gene expression and are involved in va

Externí odkaz: https://doaj.org/article/8f96cf5217e4464ca1f709df2d660cf1

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Gene and Mirna Regulatory Networks During Different Stages of Crohn’s Disease

Autor: Bram Verstockt, Severine Vermeire, Kathleen Machiels, Paul Rutgeerts, Ingrid Arijs, Jan Van der Goten, Leentje Van Lommel, Frans Schuit, Maaike Vancamelbeke, Marc Ferrante, Gert De Hertogh, Isabelle Cleynen, Gert Van Assche, Sare Verstockt

Publikováno v: Journal of Crohn's and Colitis. 13:916-930

Background and Aims Early treatment of Crohn’s disease [CD] is required in order to optimize patient outcomes. To this end, we need to gain a better understanding of the molecular changes at the onset of CD. Methods As a model for the earliest muco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355c8660cd18f6c22ba6a2d906fa80f0
https://doi.org/10.1093/ecco-jcc/jjz007

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Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease

Autor: Marc Ferrante, Ingrid Arijs, Leentje Van Lommel, Gert De Hertogh, Jan Van der Goten, Kris Nys, Gert Van Assche, Paul Rutgeerts, Sebastiaan De Schepper, Severine Vermeire, Anica Schraenen, Wiebe Vanhove, Dominiek Staelens, Paul Peeters, Emiel F.M. Wouters, Frans Schuit, Isabelle Cleynen, Niki L. Reynaert

Publikováno v: Inflammatory Bowel Diseases, 21(11), 2673-2682. LIPPINCOTT WILLIAMS & WILKINS

BACKGROUND: Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gut, partly driven by defects in the innate immune system. Considering the central role of inflammasome signaling in innate immunity, we studied inflammaso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f3dd90bca7a4b3021a7eef57773560
https://pubmed.ncbi.nlm.nih.gov/26313692

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Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress

Autor: Ingrid Arijs, Kris Nys, Eveline Hoefkens, Severine Vermeire, Isabelle Cleynen, Gert Van Assche, Jan Van der Goten, Paul Rutgeerts, Jestinah M. Mahachie John, Patrizia Agostinis, Kristel Van Steen

Publikováno v: Autophagy. 9(12)

Genome-wide association studies have identified several genes implicated in autophagy (ATG16L1, IRGM, ULK1, LRRK2, and MTMR3), intracellular bacterial sensing (NOD2), and endoplasmic reticulum (ER) stress (XBP1 and ORMDL3) to be associated with Crohn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159a955fb83c5b4a77a693c6eb280fb0
https://pubmed.ncbi.nlm.nih.gov/24247223

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Intestinal expression of SHIP in inflammatory bowel diseases

Autor: Jan Van der Goten, Severine Vermeire, Gert De Hertogh, Ingrid Arijs, Paul Rutgeerts, Frans Schuit, Bart Lemmens

Publikováno v: Gut

Background Inflammatory bowel disease (IBD) can arise from genetic mutations that compromise intestinal epithelial cell integrity or immune regulation. SHIP has previously been shown to play a pivotal role in limiting the number of immunoregulatory c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e309db1aaf045f328af933ce51b7abb
https://doi.org/10.1136/gutjnl-2011-301256

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Integrated miRNA and mRNA Expression Profiling in Inflamed Colon of Patients with Ulcerative Colitis

Autor: Marc Ferrante, Jan Van der Goten, Paul Rutgeerts, Gert De Hertogh, Ingrid Arijs, Gert Van Assche, Leentje Van Lommel, Katleen Lemaire, Wiebe Vanhove, Vicky De Preter, Kathleen Machiels, Severine Vermeire, Willem-Jan Wollants, Frans Schuit

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 12, p e116117 (2014)

Background Ulcerative colitis (UC) is associated with differential colonic expression of genes involved in immune response (e.g. IL8) and barrier integrity (e.g. cadherins). MicroRNAs (miRNAs) are regulators of gene expression and are involved in var

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bc2429ce4f9da3047cda277abd43a6
https://doi.org/10.1371/journal.pone.0116117

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