Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Jan Trapman"'
Autor:
Hanneke Korsten, Angelique C J Ziel-van der Made, Wytske M van Weerden, Theo van der Kwast, Jan Trapman, Petra W Van Duijn
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147500 (2016)
Previously, we generated a preclinical mouse prostate tumor model based on PSA-Cre driven inactivation of Pten. In this model homogeneous hyperplastic prostates (4-5m) developed at older age (>10m) into tumors. Here, we describe the molecular and his
Externí odkaz:
https://doaj.org/article/04529b4168a7415d832f1d571e13be43
Autor:
Delila Gasi, Hetty A van der Korput, Hannie C Douben, Annelies de Klein, Corrina M de Ridder, Wytske M van Weerden, Jan Trapman
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16332 (2011)
ETV1 is overexpressed in a subset of clinical prostate cancers as a fusion transcript with many different partners. However, ETV1 can also be overexpressed as a full-length transcript. Full-length ETV1 protein functions differently from truncated ETV
Externí odkaz:
https://doaj.org/article/5261daadce8e4ba5b780818aa4baaecc
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5662 (2009)
The PSA-Cre;Pten-loxP/loxP mouse prostate cancer model displays clearly defined stages of hyperplasia and cancer. Here, the initial stages of hyperplasia development are studied. Immunohistochemical staining showed that accumulated pAkt+ hyperplastic
Externí odkaz:
https://doaj.org/article/2f878e637fdf4a81b3fbf382b0564de8
Autor:
Jan Trapman, Paul C.M.S. Verhagen, Guido Jenster, Geert J.H.L. van Leenders, Delila Gasi, Joost L. Boormans, Karin G. Hermans
Supplementary Data from Overexpression of Prostate-Specific TMPRSS2(exon 0)-ERG Fusion Transcripts Corresponds with Favorable Prognosis of Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88260876a938cd3a4ddb8c5070a6341f
https://doi.org/10.1158/1078-0432.22439311.v1
https://doi.org/10.1158/1078-0432.22439311.v1
Autor:
Jan Trapman, Paul C.M.S. Verhagen, Guido Jenster, Geert J.H.L. van Leenders, Delila Gasi, Joost L. Boormans, Karin G. Hermans
Purpose: To gain insight in the mechanism and clinical relevance of TMPRSS2-ERG expression in prostate cancer, we determined the specific characteristics of fusion transcripts starting at TMPRSS2 exon 1 and at a more upstream and less characterized e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac98bf1f3e1f052dd0c4a4f68f4a1c30
https://doi.org/10.1158/1078-0432.c.6516799.v1
https://doi.org/10.1158/1078-0432.c.6516799.v1
Autor:
Guido Jenster, Jan Trapman, Chris H. Bangma, Wytske M. van Weerden, Antoine Veldhoven, Koichi Kokame, Natasja F.J. Dits, Peter J.M. Hendriksen
Supplementary Figures S1-S4 from Evolution of the Androgen Receptor Pathway during Progression of Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17346b68de123f8364ebde465934283f
https://doi.org/10.1158/0008-5472.22365254.v1
https://doi.org/10.1158/0008-5472.22365254.v1
Autor:
Guido Jenster, Jan Trapman, Chris H. Bangma, Wytske M. van Weerden, Antoine Veldhoven, Koichi Kokame, Natasja F.J. Dits, Peter J.M. Hendriksen
Supplementary Methods from Evolution of the Androgen Receptor Pathway during Progression of Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132f716af834e8b9cd02cd8aa293c831
https://doi.org/10.1158/0008-5472.22365251
https://doi.org/10.1158/0008-5472.22365251
Autor:
Jan Trapman, Guido Jenster, Natasja F. Dits, Hetty A. van der Korput, Anke A. Bressers, Karin G. Hermans
Supplementary Table 1 from Two Unique Novel Prostate-Specific and Androgen-Regulated Fusion Partners of ETV4 in Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122c823049e53eca6b4befbb36916b1b
https://doi.org/10.1158/0008-5472.22373597.v1
https://doi.org/10.1158/0008-5472.22373597.v1
Autor:
Jan Trapman, Guido Jenster, Robert Kraaij, Hanneke Korsten, Chris H. Bangma, Herman van Dekken, Theo H. van der Kwast, Joost L. Boormans, Natasja F. Dits, Angelique Ziel-van der Made, Dennis J. van de Wijngaart, Ronald van Marion, Hetty A. van der Korput, Karin G. Hermans
Supplementary Figure 5 from Truncated ETV1, Fused to Novel Tissue-Specific Genes, and Full-Length ETV1 in Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9499a8d62ec1a23a44bf0f9e861ec128
https://doi.org/10.1158/0008-5472.22375017.v1
https://doi.org/10.1158/0008-5472.22375017.v1
Autor:
Jan Trapman, Wytske M. van Weerden, Guido Jenster, Herman van Dekken, Ronald van Marion, Karin G. Hermans
Supplementary Table S1 from TMPRSS2:ERG Fusion by Translocation or Interstitial Deletion Is Highly Relevant in Androgen-Dependent Prostate Cancer, But Is Bypassed in Late-Stage Androgen Receptor–Negative Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58155d8d7a406f69340f1b3320d3912a
https://doi.org/10.1158/0008-5472.22366649.v1
https://doi.org/10.1158/0008-5472.22366649.v1