The transmembrane domain C of AMPA receptors is critically involved in receptor function and modulation

Autor: Jan Terhag, Kevin Gottschling, Michael Hollmann

Publikováno v: Frontiers in Molecular Neuroscience, Vol 3 (2010)

Ionotropic glutamate receptors are major players in synaptic transmission and are critically involved in many cognitive events. Although receptors of different subfamilies serve different functions, they all show a conserved domain topology. For most

Externí odkaz: https://doaj.org/article/41f0b6d483af4dc6a9d827542203b92b

Structural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A)

Autor: Fabian Hertel, Michael Pusch, Eric Schulze-Bahr, Nathalie Strutz-Seebohm, Lutz Pott, Markus Dicks, Veronika Matschke, Jan Terhag, Guiscard Seebohm, Ina Rothenberg, Florian Lang, Michael Hollmann, Eva Wrobel, Oana N. Ursu, Raphael Stoll

Publikováno v: Pflügers Archiv 466 (2014): 1885–1897. doi:10.1007/s00424-013-1424-8
info:cnr-pdr/source/autori:Seebohm, Guiscard; Wrobel, Eva; Pusch, Michael; Dicks, Markus; Terhag, Jan; Matschke, Veronika; Rothenberg, Ina; Ursu, Oana N.; Hertel, Fabian; Pott, Lutz; Lang, Florian; Schulze-Bahr, Eric; Hollmann, Michael; Stoll, Raphael; Strutz-Seebohm, Nathalie/titolo:Structural basis of PI(4,5)P-2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A)/doi:10.1007%2Fs00424-013-1424-8/rivista:Pflügers Archiv/anno:2014/pagina_da:1885/pagina_a:1897/intervallo_pagine:1885–1897/volume:466
Pflugers Archiv

Ionotropic glutamate receptors are the most important excitatory receptors in the central nervous system, and their impairment can lead to multiple neuronal diseases. Here, we show that glutamate-induced currents in oocytes expressing GluA1 are incre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f0f26c808eae95328f6c12b747b2ff
https://doi.org/10.1007/s00424-013-1424-8

C-terminal Domains of Transmembrane α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionate (AMPA) Receptor Regulatory Proteins Not Only Facilitate Trafficking but Are Major Modulators of AMPA Receptor Function

Autor: Jan Terhag, Charlotte Sager, Michael Hollmann, Sabine Kott

Publikováno v: Journal of Biological Chemistry. 284:32413-32424

Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)-type glutamate receptors are essential players in fast synaptic transmission in the vertebrate central nervous system. Their synaptic delivery and localization as well as their electrophysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63edf19eb36b63365edb64f7aa9e76b6
https://doi.org/10.1074/jbc.m109.039891