Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Jan Ter Meulen"'
Autor:
Dennis Horvath, Nigel Temperton, Martin Mayora-Neto, Kelly Da Costa, Diego Cantoni, Reinhold Horlacher, Armin Günther, Alexander Brosig, Jenny Morath, Barbara Jakobs, Marcus Groettrup, Heinz Hoschuetzky, Jacques Rohayem, Jan ter Meulen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract SARS-CoV-2 continues to circulate in the human population necessitating regular booster immunization for its long-term control. Ideally, vaccines should ideally not only protect against symptomatic disease, but also prevent transmission via
Externí odkaz:
https://doaj.org/article/4520b07600b543c4bea38899ef4dcba3
Autor:
Kyle Pedro, Alonso Villasmil Ocando, Benjamin Primack, Meghan Langley, Theresa Ross, Jeremy Tchaicha, Michelle Ols, Jan ter Meulen, Violet Young, Gauri Kulkarni, Arman Aksoy, Rachel A Burga
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/7fe68b97f73249be9b4b5a446cd02a74
Autor:
Gabriel Helmlinger, Rachel Burga, Stanley Tam, Mithun Khattar, Scott Lajoie, Kyle Pedro, Colleen Foley, Alonso Villasmil Ocando, Jack Tremblay, Benjamin Primack, Meghan Langley, Dan Thornton, Emily Brideau, Theresa Ross, Gwen Wilmes, Sunandan Saha, Jeremy Tchaicha, Dhruv Sethi, Michelle Ols, Gary Vanasse, Shyam Subramanian, Jan ter Meulen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/96bcf551331a468aa219481d0e648459
Autor:
Jardin A Leleux, Tina C Albershardt, Rebecca Reeves, Reice James, Jordan Krull, Andrea J Parsons, Jan Ter Meulen, Peter Berglund
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0259301 (2021)
Systemic interleukin-12 (IL12) anti-tumor therapy is highly potent but has had limited utility in the clinic due to severe toxicity. Here, we present two IL12-expressing vector platforms, both of which can overcome the deficiencies of previous system
Externí odkaz:
https://doaj.org/article/b0930d7daf3d499b8f67741020c6c439
Autor:
Neeta Somaiah, Sant P. Chawla, Matthew S. Block, John C. Morris, Khanh Do, Joseph W. Kim, Mihaela Druta, Kamalesh K. Sankhala, Patrick Hwu, Robin L. Jones, Sacha Gnjatic, Seunghee Kim-Schulze, Kevin Tuballes, Mahlet Yishak, Hailing Lu, Adam Yakovich, Jan Ter Meulen, Michael Chen, Richard T. Kenney, Chet Bohac, Seth M. Pollack
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Preclinical data suggest that a “prime-boost” vaccine regimen using a target-expressing lentiviral vector for priming, followed by a recombinant protein boost, may be effective against cancer; however, this strategy has not been evaluated in a cl
Externí odkaz:
https://doaj.org/article/aeaf8cf7e6dc4867be463362683d875c
Autor:
Xishan Lu, Haixia Xiao, Shihua Li, Xuefei Pang, Jian Song, Sheng Liu, Huijun Cheng, Yan Li, Xiangxi Wang, Chaobin Huang, Tianling Guo, Jan ter Meulen, Stephane Daffis, Jinghua Yan, Lianpan Dai, Zihe Rao, Hans-Dieter Klenk, Jianxun Qi, Yi Shi, George F. Gao
Publikováno v:
Cell Reports, Vol 26, Iss 2, Pp 438-446.e5 (2019)
Summary: Yellow fever virus (YFV), a deadly human pathogen, is the prototype of the genus Flavivirus. Recently, YFV re-emerged in Africa and Brazil, leading to hundreds of deaths, with some cases imported to China. Prophylactic or therapeutic counter
Externí odkaz:
https://doaj.org/article/c3a5fa3ab3944365be3c35854778caa6
Autor:
Dhanasekaran Govindarajan, Liming Guan, Steven Meschino, Arthur Fridman, Ansu Bagchi, Irene Pak, Jan ter Meulen, Danilo R Casimiro, Andrew J Bett
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152209 (2016)
Dengue is one of the most important mosquito-borne infections accounting for severe morbidity and mortality worldwide. Recently, the tetravalent chimeric live attenuated Dengue vaccine Dengvaxia® was approved for use in several dengue endemic countr
Externí odkaz:
https://doaj.org/article/d9159dd00b534679b40888da1c3e0a7b
Autor:
Tina Chang Albershardt, David James Campbell, Andrea Jean Parsons, Megan Merrill Slough, Jan ter Meulen, Peter Berglund
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
We have engineered an integration-deficient lentiviral vector, LV305, to deliver the tumor antigen NY-ESO-1 to human dendritic cells in vivo through pseudotyping with a modified Sindbis virus envelop protein. Mice immunized once with LV305 developed
Externí odkaz:
https://doaj.org/article/de29d2fa3b1e4650890b61e209ffe947
Autor:
Jan ter Meulen, Stephen R. Brady
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 1, Pp 15-16 (2017)
Externí odkaz:
https://doaj.org/article/303c0b9015484c3694318e5240d956c7
Autor:
Rami Sommerstein, Lukas Flatz, Melissa M Remy, Pauline Malinge, Giovanni Magistrelli, Nicolas Fischer, Mehmet Sahin, Andreas Bergthaler, Sebastien Igonet, Jan Ter Meulen, Dorothée Rigo, Paolo Meda, Nadia Rabah, Bruno Coutard, Thomas A Bowden, Paul-Henri Lambert, Claire-Anne Siegrist, Daniel D Pinschewer
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005276 (2015)
Arenaviruses such as Lassa virus (LASV) can cause severe hemorrhagic fever in humans. As a major impediment to vaccine development, delayed and weak neutralizing antibody (nAb) responses represent a unifying characteristic of both natural infection a
Externí odkaz:
https://doaj.org/article/88adfa2938774026b7ab7e3f585a6933