Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jan Taipalensuu"'
Publikováno v:
British Journal of Clinical Pharmacology. 65:69-77
Azathioprine and 6-mercaptopurine are steroid-sparing drugs used in inflammatory bowel disease (IBD). The polymorphic enzyme thiopurine S-methyltransferase (TPMT) is of importance for thiopurine metabolism and occurrence of adverse events. The role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbd18f94125545c11a9d128471804c2
https://doi.org/10.1111/j.1365-2125.2007.02985.x
https://doi.org/10.1111/j.1365-2125.2007.02985.x
Publikováno v:
Hereditas. 122:95-98
In summary, we conclude that MA and MB myrosinase genes contain the same set of 12 exons and that data neither support nor exclude the possibility that the portion of the enzyme encoded by exons 9 and 10 contains the ascorbate binding site of the mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e6a433a3a3534195a83558f3c479053
https://doi.org/10.1111/j.1601-5223.1995.00095.x
https://doi.org/10.1111/j.1601-5223.1995.00095.x
Autor:
Staffan Tavelin, Vanessa Moore, Finn Hallböök, Per Artursson, Jan Taipalensuu, Kati-Sisko Vellonen
Publikováno v:
Pharmaceutical Research. 20:373-381
Purpose. To improve the viability of the 2/4/A1 cell culture model and to investigate different routes of drug transport in this cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::745fc4e4c7de9cdc6f01a6af8c9b85d2
https://doi.org/10.1023/a:1022643802296
https://doi.org/10.1023/a:1022643802296
Autor:
Per Artursson, Staffan Tavelin, Jan Taipalensuu, Saeho Chong, Lauri Söderberg, Richard A. Morrison
Publikováno v:
Pharmaceutical Research. 20:397-405
Purpose. To characterize the paracellular route of 2/4/A1 monolayers and to compare the permeabilities of incompletely absorbed oral drugs in 2/4/A1 with those in Caco-2 monolayers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffbbdf41231e25c68b2b26c151c9227b
https://doi.org/10.1023/a:1022699920043
https://doi.org/10.1023/a:1022699920043
Autor:
Barbara Ekbom, Erik Andreasson, Lars Rask, Susanna Eriksson, Johan Meijer, Jan Taipalensuu, Bo Pontoppidan, Georg Granér, Jiaming Zhang
Publikováno v:
Plant Physiology. 129:1592-1599
The enzyme myrosinase (EC 3.2.3.1) degrades the secondary compounds glucosinolates upon wounding and serves as a defense to generalist pests in Capparales. Certain myrosinases are present in complexes together with other proteins such as myrosinase-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f606963c28b9eba943c3f55dc9ee61
https://doi.org/10.1104/pp.003285
https://doi.org/10.1104/pp.003285
Publikováno v:
Journal of Biological Chemistry. 277:6353-6358
Many heterologous membrane proteins expressed in the yeast Saccharomyces cerevisiae fail to reach their normal cellular location and instead accumulate in stacked internal membranes. Arabidopsis thaliana plasma membrane H(+)-ATPase isoform 2 (AHA2) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653a0f85daddcc7c33fa2fcb08fade83
https://doi.org/10.1074/jbc.m109637200
https://doi.org/10.1074/jbc.m109637200
Autor:
Helena Engman, Charlotta Otter, Per Artursson, Jan Taipalensuu, Brith Leidvik, Hans Lennernäs
Publikováno v:
Journal of Pharmaceutical Sciences. 90:1736-1751
The aim of this study was to find a cell culture model of the intestinal epithelium for use in studies of CYP3A4-mediated first-pass metabolism of drugs and also for studies of the interplay between CYP3A4 metabolism and P-glycoprotein efflux. For th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c028d9212d6d756ac70d4ac0150d735
https://doi.org/10.1002/jps.1123
https://doi.org/10.1002/jps.1123
Publikováno v:
Plant Molecular Biology. 41:171-180
In order to study the expression of the induced form of myrosinase-associated protein (iMyAP), a genomic clone encoding the protein was isolated from Brassica napus. The coding portion of the gene was found to consist of five exons separated by one l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3193bcfc52b50c148ae97b7a9f10930
https://doi.org/10.1023/a:1006364607564
https://doi.org/10.1023/a:1006364607564
Publikováno v:
European Journal of Biochemistry. 250:680-688
This communication demonstrates that proteins in the family of myrosinase-binding proteins (MBP) present in seeds of Brassica napus possess lectin activity, binding most efficiently to p-aminophenyl alpha-D-mannopyranoside-agarose, and to some extent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e6c58f3304c8053b3fe4b17584898e
https://doi.org/10.1111/j.1432-1033.1997.00680.x
https://doi.org/10.1111/j.1432-1033.1997.00680.x
Publikováno v:
American journal of infection control. 35(2)
Background We observed previously that newborn infants are colonized with Staphylococcus aureus , even if their mothers do not carry S aureus . This observation indicated a cross colonization, and, thus, a risk for nosocomial infection, although the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c98a0f17333978ee0cb99206ca15629
https://pubmed.ncbi.nlm.nih.gov/17327192
https://pubmed.ncbi.nlm.nih.gov/17327192