Highly Specific and Sensitive Target Binding by the Humanized pS396-Tau Antibody hC10.2 Across a Wide Spectrum of Alzheimer’s Disease and Primary Tauopathy Postmortem Brains

Autor: Lone Helboe, Nina Rosenqvist, Christiane Volbracht, Lars Ø. Pedersen, Jan T. Pedersen, Søren Christensen, Jan Egebjerg, Claus T. Christoffersen, Benny Bang-Andersen, Thomas G. Beach, Geidy E. Serrano, Jeppe Falsig

Publikováno v: Journal of Alzheimer's Disease. 88:207-228

Background: Deposits of hyperphosphorylated tau fibrils are hallmarks of a broad spectrum of tauopathies, including Alzheimer’s disease (AD). Objective: To investigate heterogeneity of tau pathology across brain extracts from a broad selection of d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b02055038581d809760d2e5e312230
https://doi.org/10.3233/jad-220125

List of Contributors

Autor: Emaad M. Abdel-Rahman, Hayley D. Ackerman, Abimbola Akintola, Gro V. Amdam, Gil Atzmon, Steve Austad, Sanket Awate, Márta Balaskó, Taraswi Banerjee, Clea Bárcena, Andrzej Bartke, Ivan Bassi, Mette Berendt, Maarten F. Bijlsma, Alessandro Bitto, Jennifer L. Bizon, Ilse Bollaerts, Marco Bonomi, Consuelo Borras, Brendan T. Bowman, Thomas Brioche, Robert M. Brosh, Richard E. Brown, Kerstin Buck, Sara N. Burke, Wanda Buzgariu, Ramón Cacabelos, M.A. Camina Martín, Beth K. Chaffee, Anthony W.S. Chan, Haolin Chen, Zhiguo Chen, In K. Cho, Angèle Chopard, Victoria C. Cogger, Alan A. Cohen, Rafael Confino, Fabio Coppedè, Anthony J. Costa, Jack D. Crouch, Justin Darcy, Lies De Groef, B. de Mateo Silleras, Sathyaseelan S. Deepa, Gina Devau, Marc Dhenain, Chantelle Dills, Megan F. Duffy, Francesca E. Duncan, Gilles Dupuis, Benjamin A. Eaton, Josephine M. Egan, Kazadi Ekundayo, Marina E. Emborg, D. Luke Fischer, Pascaline Fontes, Maria Lourdes Alarcon Fortepiani, Carl Fortin, Bernhard Franzke, Tamas Fülöp, Camelia Gabriel, Brigitte Galliot, Juan Gambini, Hugo Garneau, Laura Gasparini, Glenn S. Gerhard, David C. Gibson, Lucia Gimeno-Mallench, Victor Girard, Kimberly A. Greer, Kristin E. Gribble, Melanie R. Gubbels Bupp, Adalsteinn Gudmundsson, Andrea Hamann, Michael R. Hamblin, James M. Harper, Ronald Hart, Elizabeth Head, Heather R. Herd, Guadalupe Herrera, Fuki M. Hisama, David B. Hogan, Donna J. Holmes, Peter J. Hornsby, Susan E. Howlett, Ka Yi Hui, Thomas R. Jahn, Beatriz Jávega, William R. Jeffery, Sarah A. Johnson, Audrey Jones, Corinne A. Jones, Pálmi V. Jónsson, Alice E. Kane, David Karasik, Samuel Kean, Evan T. Keller, Jill M. Keller, Christopher J. Kemp, Ken S.K. Wong, Jens Krøll, Sanjay Kumar Bharti, Markku Kurkinen, Anis Larbi, Christelle Lasbleiz, Corinne Lautier, David G. Le Couteur, Aurelie Le Page, Hang Lin, Carlos López-Otín, Line Lottonen-Raikaslehto, Elizabeth R. Magden, Evgenia Makrantonaki, Fredric P. Manfredsson, David B. Mark Welch, Jose Marques-Lopes, Alicia Martínez-Romero, Cristina Mas-Bargues, Pablo Mayoral, Mark Mc Auley, Joseph A. McQuail, Mari Merentie, Nadine Mestre-Frances, Jeanette M. Metzger, Keith C. Meyer, Teresa A. Milner, Claudia M. Mizutani, Raymond J. Monnat, Kathleen Mooney, Lieve Moons, Joscha Muck, Ranganath Muniyappa, Jan O. Nehlin, Oliver Neubauer, Georgios Nikolakis, Jeffry S. Nyman, José-Enrique O’Connor, Junko Oshima, Heinz D. Osiewacz, Vassilios Papadopoulos, Mary Ellen Pavone, Graham Pawelec, Jan T. Pedersen, Gonzalo Perez-Lopez, Luca Persani, Erika Pétervári, Azadeh Peyman, Johannes F. Plate, Nicole K. Polinski, Guillaume Py, Tyler P. Quigley, Eric A. Rae, Jeffrey L. Ram, David Raubenheimer, Jane F. Reckelhoff, M.P. Redondo del Río, Jovy Rex-Al Panem Orbon, Arlan Richardson, Jürgen A. Ripperger, Ildikó Rostás, Michael Rouse, Olav Rueppell, Kurt W. Runge, Maryam Safdar, Sumathi Sankaran-Walters, Anthony C. Santago, Anneli Sarvimäki, Katherine R. Saul, Quentin Schenkelaars, Brandt L. Schneider, Trine Schütt, He Shen, Sooyoun Shin, Stephen J. Simpson, Jessica Smith, Terry W. Snell, Jessica M. Snyder, Samantha M. Solon-Biet, Szilvia Soós, Caryl E. Sortwell, Rui Sousa-Neves, Kathy Steece-Collier, Anne Steins, Alyson Sujkowski, Susan E. Swanberg, Oscar Teijido, Sri Harsha Tella, Judit Tenk, Szymon Tomczyk, Piper M. Treuting, Stéphanie G. Trouche, Rocky S. Tuan, Archana Unnikrishnan, Dario Riccardo Valenzano, Diana van Heemst, Jessie Van houcke, Tracey A. Van Kempen, Hanneke W.M. van Laarhoven, Jean-Michel Verdier, Jose Viña, Karl-Heinz Wagner, Devin Wahl, Yvan Wenger, Robert J. Wessells, Donna M. Wilcock, Jacek M. Witkowski, Esther Wong, Nicole Woodland, Licy L. Yanes Cardozo, Seppo Ylä-Herttuala, Sameh A. Youssef, Rong Yuan, Haitao Zhang, Zhongjun Zhou, Barry R. Zirkin, Christos C. Zouboulis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba7e888964939c8c6fbd5869ee76eda7
https://doi.org/10.1016/b978-0-12-811353-0.01002-2

Critical assessment of methods of protein structure prediction (CASP): Round III

Autor: John Moult, Jan T. Pedersen, Tim Hubbard, Krzysztof Fidelis

Publikováno v: Proteins: Structure, Function, and Genetics. 37:2-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7e8043bfc98f0147b4977b22369ef01
https://doi.org/10.1002/(sici)1097-0134(1999)37:3+<2::aid-prot2>3.0.co

Ab initio protein folding simulations with genetic algorithms: Simulations on the complete sequence of small proteins

Autor: John Moult, Jan T. Pedersen

Publikováno v: Proteins: Structure, Function, and Genetics. 29:179-184

Ab-initio folding simulations have been performed on three small proteins using a genetic algorithm- (GA-) based search method which operates on an all atom representation. Simulations were also performed on a number of small peptides expected to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f7299c3e6a688d8c8e02253e5ffc2fc
https://doi.org/10.1002/(sici)1097-0134(1997)1+<179::aid-prot23>3.0.co

Confronting the problem of interconnected structural changes in the comparative modeling of proteins

Autor: Huai-bei Zhou, Rui Luo, Krzysztof Fidelis, Jan T. Pedersen, Ram Samudrala, John Moult

Publikováno v: Proteins: Structure, Function, and Genetics. 23:327-336

Comparative models of three proteins have been built using a variety of computational methods, heavily supplemented by visual inspection. We consider the accuracy obtained to be worse than expected. A careful analysis of the models shows that a major

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdcc3310c3e08742289562baff97eed
https://doi.org/10.1002/prot.340230307