Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jan T Poolman"'
Autor:
Michiel Stork, Jan Grijpstra, Martine P Bos, Carmen Mañas Torres, Nathalie Devos, Jan T Poolman, Walter J Chazin, Jan Tommassen
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003733 (2013)
The outer membrane of Gram-negative bacteria functions as a permeability barrier that protects these bacteria against harmful compounds in the environment. Most nutrients pass the outer membrane by passive diffusion via pore-forming proteins known as
Externí odkaz:
https://doaj.org/article/0300639d643b4513ad6b008b8f1e66b4
Autor:
Ian R Peak, Yogitha N Srikhanta, Vincent E Weynants, Christiane Feron, Jan T Poolman, Michael P Jennings
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72003 (2013)
NhhA (Neisseria hia homologue) is an outer membrane protein from Neisseria meningitidis, the causative agent of meningococcal disease. The protein is surface exposed and its expression in a wide range of meningococcal strains suggests it is a promisi
Externí odkaz:
https://doaj.org/article/5e9f7131e6af418f80d23ef1b62291c3
Autor:
Michiel Stork, Martine P Bos, Ilse Jongerius, Natasja de Kok, Ingrid Schilders, Vincent E Weynants, Jan T Poolman, Jan Tommassen
Publikováno v:
PLoS Pathogens, Vol 6, p e1000969 (2010)
Since the concentration of free iron in the human host is low, efficient iron-acquisition mechanisms constitute important virulence factors for pathogenic bacteria. In Gram-negative bacteria, TonB-dependent outer membrane receptors are implicated in
Externí odkaz:
https://doaj.org/article/aa0cfa6d119444f98d630086e50c772e
Autor:
Jan T. Poolman, Annaliesa S. Anderson
Publikováno v:
Expert Review of Vaccines, Vol 17, Iss 7, Pp 607-618 (2018)
Introduction: Bacteremia and healthcare-associated infections (HAIs) continue to rise in industrialized countries, in line with population aging and increased healthcare needs. Escherichia coli and Staphylococcus aureus are the most common pathogens
Externí odkaz:
https://doaj.org/article/12781339e808422485f0bc1687f6b040
Autor:
Jan T, Poolman
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 164
Vaccines were originally developed to prevent potentially deadly childhood diseases, but during the 21st century attention broadened to include prevention of infection in all stages of life. Prevention and treatment of bacterial infections are two of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e51be9fd6fc59639ab06d68eea337a93
https://pubmed.ncbi.nlm.nih.gov/32940986
https://pubmed.ncbi.nlm.nih.gov/32940986
Autor:
Kellen C. Faé, Gerd Lipowsky, Ingrid M. van den Nieuwenhof, Cristina Alaimo, Joerg Schneider, Micha A. Haeuptle, Germie P J M van den Dobbelsteen, Jan T Poolman, Jan Serroyen, Dominique Sirena, Veronica Gambillara-Fonck, Michael J. Wacker, Martin Braun
Publikováno v:
Vaccine. 34:4152-4160
Background Extra-intestinal pathogenic Escherichia coli (ExPEC) are major human pathogens; however, no protective vaccine is currently available. We assessed in animal models the immunogenicity and safety of a 4-valent E. coli conjugate vaccine (ExPE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e718b4eab96bcc572a80a9e8981f45d9
https://doi.org/10.1016/j.vaccine.2016.06.067
https://doi.org/10.1016/j.vaccine.2016.06.067
Autor:
Jan T Poolman
Publikováno v:
Expert Review of Vaccines. 13:1067-1069
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6fd6bb86d6eae777b04bbb74edaf606
https://doi.org/10.1586/14760584.2014.946910
https://doi.org/10.1586/14760584.2014.946910
Autor:
Jan T Poolman
Publikováno v:
Expert review of vaccines. 13(10)
First generation whole-cell (wP) and second generation acellular (aP) pertussis vaccines have been highly effective in preventing childhood deaths due to pertussis, yet both vaccines have drawbacks that have limited their long-term usefulness. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f04d3aa3736ab31e67d7e968e12733
https://pubmed.ncbi.nlm.nih.gov/25089373
https://pubmed.ncbi.nlm.nih.gov/25089373
Autor:
Anne Marie Queenan, Selma Wiertsema, Jeffrey Fernandez, Germie P J M van den Dobbelsteen, Jan T Poolman, Wenchi Shang
Publikováno v:
Expert review of vaccines. 13(10)
A mouse intracerebral challenge model is used for potency testing of whole-cell pertussis (wP) vaccines. We investigated the use of a mouse nasopharyngeal challenge model, which better reflects the clinical features of pertussis disease, to different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1b7aeea59d71fb2ebbf31215a3c610
https://pubmed.ncbi.nlm.nih.gov/25029905
https://pubmed.ncbi.nlm.nih.gov/25029905