Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jan Svartengren"'
Autor:
Susanne Gustavsson, Elisabet Ohlin Sjöström, Agneta Tjernberg, Juliette Janson, Ulrica Westermark, Tommy Andersson, Åsa Makower, Erik Arnelöf, Gudrun Andersson, Jan Svartengren, Carina Ekholm, Stefan Svensson Gelius
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 21, Iss , Pp - (2019)
Mucopolysaccharidosis type IIIA (MPS IIIA) is a lysosomal storage disorder (LSD) characterized by severe central nervous system (CNS) degeneration. The disease is caused by mutations in the SGSH gene coding for the lysosomal enzyme sulfamidase. Sulfa
Externí odkaz:
https://doaj.org/article/5c5925a40eaf4e558c81d318fcb0dd0e
Publikováno v:
European Journal of Biochemistry. 128:481-488
Chronic catecholamine stimulation in vivo of brown adipose tissue during acclimation of hamsters to cold does not result in any alteration of beta-adrenergic receptor number or affinity when determined in isolated adipocytes by (-)-[3H]dihydroalpreno
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 44:373-380
Multivariate evaluation of pharmacological data from lean and obese mice treated with leptin has been performed. To evaluate the difference between the groups, PC models have been calculated for both food intake and body weight for the four groups. B
Publikováno v:
Biological Psychiatry. 42:247-259
Behavioral, biochemical, and electrophysiological studies suggest that amperozide affects mesolimbic and mesocortical dopamine neurotransmission. The receptor binding profile of amperozide is discussed and related to behavioral and clinical, i.e., an
Publikováno v:
CNS Drug Reviews. 2:363-383
Publikováno v:
European Journal of Pharmacology. 261:285-294
The effects of FG5893 were evaluated by several different methods; rats were used as experimental animals. Receptor binding studies revealed that FG5893 (2-(4-(4,4-bis(4-fluorophenyl)butyl)-1-piperazinyl)-3-pyridinecarboxy lic acid methyl ester) bind
Publikováno v:
Current Protocols in Pharmacology
Because of the dramatic increase in obesity and related conditions, such as type 2 diabetes, efforts have intensified to develop medications to assist in losing weight or in minimizing weight gain. To this end, methods that allow for the continuous m
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 78:159-170
1. A crude membrane fraction was prepared from hamster brown adipose tissue. Extensive washing of the crude membranes was crucial for the appearance of specific β-adrenergic receptor binding as assessed by (−)-[3H]dihydroalprenolol. 2. Adrenergic
Publikováno v:
European Journal of Biochemistry. 102:203-210
The beta-adrenergic receptors of hamster brown adipocytes have been characterised by binding of the radioactive ligand (-)-[3H]dihydroalprenolol, directly to isolated intact cells in suspension. The brown fat cell contains 57,000 specific and saturab