Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Jan Stenvang"'
Autor:
Mikkel Høeberg, Julie Boertmann Noer, Mette Vixø Vistesen, Annette Bartels, Esben Matzen Bech, Sune Boris Nygård, Ulrik Lademann, Jan Stenvang, Siqi Liu, Anja Thoe Fuglsang, Nils Brünner, José Manuel Afonso Moreira
Publikováno v:
Molecular Oncology, Vol 17, Iss 8, Pp 1595-1612 (2023)
Tissue inhibitor of metalloproteinases‐1 (TIMP‐1) regulates the proteolytic activity of matrix metalloproteinases (MMPs), playing an important role in the homeostasis of the extracellular matrix. Beyond its well‐known role in tissue maintenance
Externí odkaz:
https://doaj.org/article/514da4a7f4ac4728b3148bc37682ce11
Autor:
Cathrine Nordgaard, Sophia Doll, Ana Laura de Souza Almeida Matos, Mikkel Høeberg, Julhash Uddin Kazi, Stine Friis, Jan Stenvang, Lars Rönnstrand, Matthias Mann, José Manuel Afonso Moreira
Publikováno v:
Molecular Oncology, Vol 13, Iss 12, Pp 2646-2662 (2019)
Colorectal cancer (CRC) is the third most prevalent cancer worldwide causing an estimated 700 000 deaths annually. Different types of treatment are available for patients with advanced metastatic colorectal cancer, including targeted biological agent
Externí odkaz:
https://doaj.org/article/87c57af9390b42659c4b02cbde6c32ae
Autor:
Iben Kümler, Eva Balslev, Jan Stenvang, Nils Brünner, Bent Ejlertsen, Erik Hugger Jakobsen, Dorte Lisbet Nielsen
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-5 (2019)
Abstract Background Treatment options in metastatic breast cancer are limited. New therapies preferable with predictive biomarkers are needed. The aim of these trials was to investigate if gene copy number of the topoisomerase 1 gene was predictive o
Externí odkaz:
https://doaj.org/article/d12b0a4ca94f4d26b03f65912e1d1f84
Autor:
Peide Huang, Fengyu Li, Zongchao Mo, Chunyu Geng, Fang Wen, Chunyan Zhang, Jia Guo, Song Wu, Lin Li, Nils Brünner, Jan Stenvang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
To investigate the relationship between non-coding RNAs [especially circular RNAs (circRNAs)] and docetaxel resistance in breast cancer, and to find potential predictive biomarkers for taxane-containing therapies, we have performed transcriptome and
Externí odkaz:
https://doaj.org/article/3f68b7aa134d4ba6b94abdc8c16fd622
Autor:
Malene J. Petersen, Xamuel L. Lund, Susan J. Semple, Bevan Buirchell, Henrik Franzyk, Michael Gajhede, Kenneth T. Kongstad, Jan Stenvang, Dan Staerk
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1534 (2021)
Multidrug resistance (MDR) is a major challenge in cancer treatment, and the breast cancer resistance protein (BCRP) is an important target in the search for new MDR-reversing drugs. With the aim of discovering new potential BCRP inhibitors, the crud
Externí odkaz:
https://doaj.org/article/1ef47aeb6a98488680ce7c6e9308502c
Autor:
Marie Stampe Ostenfeld, Steffen Grann Jensen, Dennis Kjølhede Jeppesen, Lise-Lotte Christensen, Stine Buch Thorsen, Jan Stenvang, Michael Lykke Hvam, Anni Thomsen, Peter Mouritzen, Mads Heilskov Rasmussen, Hans Jørgen Nielsen, Torben Falck Ørntoft, Claus Lindbjerg Andersen
Publikováno v:
Journal of Extracellular Vesicles, Vol 5, Iss 0, Pp 1-14 (2016)
Cancer cells secrete small membranous extracellular vesicles (EVs) into their microenvironment and circulation. These contain biomolecules, including proteins and microRNAs (miRNAs). Both circulating EVs and miRNAs have received much attention as bio
Externí odkaz:
https://doaj.org/article/77599075068143c488b5734becc9478e
Autor:
Anne-Marie Ellegaard, Christian Dehlendorff, Anna C. Vind, Atul Anand, Luise Cederkvist, Nikolaj H.T. Petersen, Jesper Nylandsted, Jan Stenvang, Anders Mellemgaard, Kell Østerlind, Søren Friis, Marja Jäättelä
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 130-139 (2016)
Non-small cell lung cancer (NSCLC) is one of the deadliest cancers worldwide. In search for new NSCLC treatment options, we screened a cationic amphiphilic drug (CAD) library for cytotoxicity against NSCLC cells and identified several CAD antihistami
Externí odkaz:
https://doaj.org/article/94f6107f21284c638eba81b3ff22ed6b
Autor:
Sophie E. B. Ambjørner, Michael Wiese, Sebastian Christoph Köhler, Joen Svindt, Xamuel Loft Lund, Michael Gajhede, Lasse Saaby, Birger Brodin, Steffen Rump, Henning Weigt, Nils Brünner, Jan Stenvang
Publikováno v:
Cells, Vol 9, Iss 3, p 613 (2020)
ATP-binding cassette (ABC) transporters, such as breast cancer resistance protein (BCRP), are key players in resistance to multiple anti-cancer drugs, leading to cancer treatment failure and cancer-related death. Currently, there are no clinically ap
Externí odkaz:
https://doaj.org/article/9125fa0623474914a400472c345ff3b3
Autor:
Erika Assarsson, Martin Lundberg, Göran Holmquist, Johan Björkesten, Stine Bucht Thorsen, Daniel Ekman, Anna Eriksson, Emma Rennel Dickens, Sandra Ohlsson, Gabriella Edfeldt, Ann-Catrin Andersson, Patrik Lindstedt, Jan Stenvang, Mats Gullberg, Simon Fredriksson
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95192 (2014)
Medical research is developing an ever greater need for comprehensive high-quality data generation to realize the promises of personalized health care based on molecular biomarkers. The nucleic acid proximity-based methods proximity ligation and prox
Externí odkaz:
https://doaj.org/article/e2de90278afd47aebacc53f5871053c0
The invariant chain CD74 protein is a cell surface binding partner of TIMP ‐1 in breast cancer cells
Autor:
Mikkel Høeberg, Julie Boertmann Noer, Mette Vixø Vistesen, Annette Bartels, Esben Matzen Bech, Sune Boris Nygård, Ulrik Lademann, Jan Stenvang, Siqi Liu, Anja Thoe Fuglsang, Nils Brünner, José Manuel Afonso Moreira
Publikováno v:
Molecular Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb908cb4fd74613896270adffe799c14
https://doi.org/10.1002/1878-0261.13436
https://doi.org/10.1002/1878-0261.13436