Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jan St. Pyrek"'
Autor:
Jan St. Pyrek, Atish Mukherjee, Muthoni Kihiko-Ehmann, Louis B. Hersh, Eun-Suk Song, Jack P. Goodman, Steven Estus
Publikováno v:
The Journal of Neuroscience. 20:8745-8749
Insulysin (EC. 3.4.22.11) has been implicated in the clearance of β amyloid peptides through hydrolytic cleavage. To further study the action of insulysin on Aβ peptides recombinant rat insulysin was used. Cleavage of both Aβ1–40and Aβ1–42by
Autor:
Jan St. Pyrek
Publikováno v:
Synlett. 1999:249-266
Publikováno v:
Journal of Heterocyclic Chemistry. 30:1645-1651
Two synthetic strategies permitted the synthesis of various metabolites of detomidine (1) and medetomidine (4), potent α-2 adrenoceptor agonists that undergo rapid oxidative metabolism at the aromatic methyl group distal to the imidazole ring. In th
Publikováno v:
Journal of Chemical Ecology. 19:2981-2997
Lycopersicon hirsutum, a wild relative of the tomato, is highly resistant to arthropod herbivores. Both botanic forms ofL. hirsutum, L. hirsutum f.glabratum (C.H. Mull.) andL. hirsutum f.typicum (Humb. & Bonpl.), are resistant to two-spotted spider m
Autor:
Jan St. Pyrek, Robert M. Carlson, Ewa Kolaczkowska, J. Michael Moldowan, Frederick J. Fago, Ivan L. Stoilov, David S. Watt
Publikováno v:
The Journal of Organic Chemistry. 58:3444-3454
Efficient routes for the preparation of selected C-23 and C-24 diastereomers of the C 30 biological markers 4α-methyl-5α-stigmastane (1) and 5α-dinosterane (2) involved the alkylation of 20-(iodomethyl)-4α-methyl-5α-pregnane with either saturate
Autor:
Jan St. Pyrek, F. J. Fago, Ewa Kolaczkowska, R. M. K. Carlson, Ivan Stoilov, David S. Watt, J. M. Moldowan
Publikováno v:
ChemInform. 24
Autor:
Robert M. Carlson, R. Shetty, Jan St. Pyrek, David S. Watt, W. J. Layton, J. M. Moldowan, Ivan Stoilov, Stanford L. Smith
Publikováno v:
ChemInform. 25
Publikováno v:
ChemInform. 25
Two synthetic strategies permitted the synthesis of various metabolites of detomidine (1) and medetomidine (4), potent α-2 adrenoceptor agonists that undergo rapid oxidative metabolism at the aromatic methyl group distal to the imidazole ring. In th
Autor:
Jan St. Pyrek
Publikováno v:
ChemInform. 30
Autor:
Jan St. Pyrek, Ivan Stoilov, Carolyn Pratt Brock, J. Michael Moldowan, Robert M. K. Carlson, David S. Watt, Ewa Kolaczkowska
Publikováno v:
Tetrahedron Letters. 33:7689-7692
Stereoselective routes for the preparation of C-23 and C-24 diastereomers of the C30 biological marker, 5α-dinosterane (1), involved the alkylation of (20S)-20-(iodomethyl)-4α-methyl-5α-pregnane (7) with either a saturated ester, methyl 3,4-dimeth