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pro vyhledávání: '"Jan Soroczynski"'
Publikováno v:
Bio-Protocol, Vol 14, Iss 6 (2024)
CRISPR/Cas9 genome editing is a widely used tool for creating genetic knock-ins, which allow for endogenous tagging of genes. This is in contrast with random insertion using viral vectors, where expression of the inserted transgene changes the total
Externí odkaz:
https://doaj.org/article/72649e21b51a42999df9f3d255afd9b6
Macrophages must respond appropriately to pathogens and other pro-inflammatory stimuli in order to perform their roles in fighting infection. One way in which inflammatory stimuli can vary is in their dynamics – that is, the amplitude and duration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51b79dab3c3f89bc7785888443b6b0e6
https://doi.org/10.1101/2023.05.19.541501
https://doi.org/10.1101/2023.05.19.541501
Autor:
Tony Hunter, Karen H. Miga, Nien Hoong, Sven Heinz, Quan Zhu, Toshiro Hara, Christopher Benner, John R. Yates, Inder M. Verma, Sachin Verma, Eugene Ke, Jan Soroczynski, Aaron Aslanian
Publikováno v:
Molecular cell. 70(5)
Heterochromatic repetitive satellite RNAs are extensively transcribed in a variety of human cancers, including BRCA1 mutant breast cancer. Aberrant expression of satellite RNAs in cultured cells induces the DNA damage response, activates cell cycle c