Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Jan Skrha"'
Autor:
Jiri Plasek, Jozef Dodulik, Petr Gai, Barbora Hrstkova, Jan Skrha, Lukas Zlatohlavek, Renata Vlasakova, Peter Danko, Petr Ondracek, Eva Cubova, Bronislav Capek, Marie Kollarova, Tomas Furst, Jan Vaclavik
Publikováno v:
Biomedical Papers, Vol 168, Iss 1, Pp 35-43 (2024)
Introduction. SARS-CoV-2 respiratory infection is associated with significant morbidity and mortality, especially in hospitalized high-risk patients. We aimed to evaluate the effects of treatment options (vitamin D, anticoagulation, isoprinosine, ive
Externí odkaz:
https://doaj.org/article/96170ca6a8a748898270490506665594
Autor:
Jan Bures, Darina Kohoutova, Jan Skrha, Bohus Bunganic, Ondrej Ngo, Stepan Suchanek, Pavel Skrha, Miroslav Zavoral
Publikováno v:
Cancers, Vol 15, Iss 14, p 3669 (2023)
Background: Pancreatic ductal adenocarcinoma (PDAC) is associated with a very poor prognosis, with near-identical incidence and mortality. According to the World Health Organization Globocan Database, the estimated number of new cases worldwide will
Externí odkaz:
https://doaj.org/article/da52369112854cd48ff16aaed1155673
Autor:
Oliver Schnell, Eberhard Standl, Doina Catrinoiu, Baruch Itzhak, Nebojsa Lalic, Dario Rahelic, Jan Skrha, Paul Valensi, Antonio Ceriello
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-8 (2019)
Abstract The 4th Cardiovascular Outcome Trial (CVOT) Summit of the Diabetes & Cardiovascular Disease (D&CVD) EASD Study Group was held in Munich on 25–26 October 2018. As in previous years, this summit served as a reference meeting for in-depth dis
Externí odkaz:
https://doaj.org/article/edff8e1892e84ccc8e56ef808b78e3f8
Autor:
Oliver Schnell, Eberhard Standl, Doina Catrinoiu, Stefano Genovese, Nebojsa Lalic, Katarina Lalic, Jan Skrha, Paul Valensi, Antonio Ceriello
Publikováno v:
Cardiovascular Diabetology, Vol 17, Iss 1, Pp 1-6 (2018)
Abstract The 3rd Cardiovascular Outcome Trial Summit of the Diabetes & Cardiovascular Disease EASD Study Group was held on the 26–27 October 2017 in Munich. As in 2015 and 2016, this summit was organised in light of recently completed and published
Externí odkaz:
https://doaj.org/article/6b7f36a96ddb4742a7560334c420e04f
Publikováno v:
Diabetes. 69
Endothelial activation accelerated by oxidative stress (OxS) is believed to be the major step in development of diabetes angiopathy. The aim of this follow-up study was to measure microvascular reactivity (MVR) and markers of OxS. Our study involved
Publikováno v:
Diabetes. 68
Nondiabetic hypoglycemia may be caused by hepatic or renal failure, drugs, malnutrition, malignancy or functional changes. The fasting test may be used to distinguish organic hypoglycemia by insulinoma from functional (reactive) hypoglycemia. The aim
Publikováno v:
Vnitrni lekarstvi. 60(9)
Receptor for advanced glycation end-products plays a crucial role in chronic diabetes complications. It is supposed to be involved in the development of all kinds of diabetic angiopathy. Advanced glycation end-products (AGEs) excessively accumulated
Autor:
John A, Dormandy, Bernard, Charbonnel, David J A, Eckland, Erland, Erdmann, Massimo, Massi-Benedetti, Ian K, Moules, Allan M, Skene, Meng H, Tan, Pierre J, Lefèbvre, Gordon D, Murray, Eberhard, Standl, Robert G, Wilcox, Lars, Wilhelmsen, John, Betteridge, Kåre, Birkeland, Alain, Golay, Robert J, Heine, László, Korányi, Markku, Laakso, Marián, Mokán, Antanas, Norkus, Valdis, Pirags, Toomas, Podar, André, Scheen, Werner, Scherbaum, Guntram, Schernthaner, Ole, Schmitz, Jan, Skrha, Ulf, Smith, Jan, Taton, T D M, Williams
Publikováno v:
Dormandy, J A, Charbonnel, B, Eckland, D J, Erdmann, E, Massi-Benedetti, M, Moules, I K, Skene, A M, Tan, M H, Lefebvre, P J, Murray, G D, Standl, E & Wilcox, R G 2005, ' Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial ', Lancet, vol. 366, no. 9493, pp. 1279-1289 . https://doi.org/10.1016/S0140-6736(05)67528-9
Dormandy, J A, Charbonnel, B, Eckland, D J, Erdmann, E, Massi-Benedetti, M, Moules, I K, Skene, A M, Tan, M H, Lefebvre, P J, Murray, G D, Standl, E, Wilcox, R G, Wilhelmsen, L, Betteridge, J, Birkeland, K, Golay, A, Heine, R J, Koranyi, L, Laakso, M, Mokan, M, Norkus, A, Pirags, V, Podar, T, Scheen, A, Scherbaum, W, Schernthaner, G, Schmitz, O, Skrha, J, Smith, U & Taton, J 2005, ' Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial ', The Lancet, vol. 366(9493), pp. 1279-1289 .
Lancet, 366(9493), 1279-1289. Elsevier Limited
Dormandy, J A, Charbonnel, B, Eckland, D J, Erdmann, E, Massi-Benedetti, M, Moules, I K, Skene, A M, Tan, M H, Lefebvre, P J, Murray, G D, Standl, E, Wilcox, R G, Wilhelmsen, L, Betteridge, J, Birkeland, K, Golay, A, Heine, R J, Koranyi, L, Laakso, M, Mokan, M, Norkus, A, Pirags, V, Podar, T, Scheen, A, Scherbaum, W, Schernthaner, G, Schmitz, O, Skrha, J, Smith, U & Taton, J 2005, ' Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial ', The Lancet, vol. 366(9493), pp. 1279-1289 .
Lancet, 366(9493), 1279-1289. Elsevier Limited
Patients with type 2 diabetes are at high risk of fatal and non-fatal myocardial infarction and stroke. There is indirect evidence that agonists of peroxisome proliferator-activated receptor gamma (PPAR gamma) could reduce macrovascular complications
Autor:
Jan, Skrha
Publikováno v:
Casopis lekaru ceskych. 149(6)
Type 2 diabetes mellitus develops as a combination of genetic background and external factors. The disease development is caused by increased oxidative stress under various metabolic factors and in parallel by complex inflammatory reaction without cl
Autor:
Jan, Skrha
Publikováno v:
Advances in clinical chemistry. 47
Caloric restriction is associated with a decreased level of oxidative stress. Reactive oxygen species (ROS) generated predominantly in mitochondria are attenuated by decreased caloric intake. On the other hand, antioxidative mechanisms are frequently